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Feraheme as safe and effective as iron sucrose in patients with anemia, CKD

AMAG Pharmaceuticals, Inc. today announced positive new data from the FIRST head-to-head trial comparing Feraheme (ferumoxytol) Injection for intravenous (IV) use to iron sucrose in patients with iron deficiency anemia and chronic kidney disease.

14 Nov 2011

New information on kidney-related policies in the U.S.

Two studies presented during the American Society of Nephrology's Annual Kidney Week provide new information on kidney-related policies in the United States.

14 Nov 2011

NIDDK-funded study to develop approaches for chronic kidney disease management

Cleveland Clinic nephrologist Joseph Nally Jr., M.D., has been awarded a three-year, $720,000 grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) to study and develop approaches for disease management for patients with chronic kidney disease.

14 Nov 2011

Sitagliptin as safe and effective as glipizide in patients with type 2 diabetes, CKD

Some blood-sugar-lowering drugs have caused kidney problems in patients with type 2 diabetes, so physicians are especially cautious when prescribing these agents to diabetics who also have chronic kidney disease.

14 Nov 2011

Opioid-dependent patients have worse outcomes before knee replacement surgery

Patients who are dependent on opioids (narcotic pain relievers) for pain management before knee replacement surgery have much more difficulty recovering, a study recently published in the Journal of Bone and Joint Surgery (JBJS) has found.

13 Nov 2011

Salt – is it bad for the heart? Debate continues

Salt or high sodium intake in diet has drawn attention of researchers for a while now. The U.S. Food and Drug Administration held a day-long hearing today, discussing strategies to help Americans cut the salt from their diets as a latest attempt to curb sodium in the American diet.

13 Nov 2011

Updates on dietary benefits and dangers in kidney disease patients

Two studies presented during the American Society of Nephrology's Annual Kidney Week provide new information on dietary benefits and dangers in kidney disease patients.

11 Nov 2011

Research roundup: Cutting speciality care by raising co-payments; Asthma diagnosis and insurance coverage; GAO on early retirees

Mayo Clinic Employees Responded To New Requirements For Cost Sharing By Reducing Possibly Unneeded Health Services Use -- Researchers at the Mayo Clinic examined the effects of changes in the clinic's self-funded health plan "to decrease the use of potentially inappropriate health care services and foster a deliver system centered on primary care."

11 Nov 2011

Multimodal interdisciplinary strategy needed to treat resistant arterial hypertension

Five to 15 percent of all patients with hypertension fail to respond to drug treatment. However, a range of treatment options are now available in these cases.

11 Nov 2011

NYU Langone professor offers guidance on risk factors, interventions for SUDEP

Over time, epileptic seizures can lead to major health issues, including significant cognitive decline and even death, warns Orrin Devinsky, MD, professor, Departments of Neurology, Neurosurgery and Psychiatry at NYU Langone Medical Center.

11 Nov 2011

Conference highlights advances in evidence-based integrative therapies for cancer

Today the Society for Integrative Oncology highlighted top research findings presented at the Eighth International Conference this week in Cleveland, Ohio. More than 80 abstracts will be presented at the annual meeting, which will be keynoted by National Institutes of Health Director, Francis Collins, MD, PhD.

11 Nov 2011

Johns Hopkins to establish new global center for childhood obesity

The Johns Hopkins Bloomberg School of Public Health has been awarded a $16 million U54 cooperative agreement from the National Institutes of Health (NIH) to establish a global center of excellence to address the childhood obesity epidemic.

11 Nov 2011

Study reveals risk factors for temporomandibular disorders

Now, for the first time, researchers in the University at Buffalo School of Dental Medicine are publishing a comprehensive set of clinical characteristics that they say will lead to the ability to identify individuals at risk for developing the painful conditions. Their new clinical assessments will help researchers and clinicians better understand TMD and other pain conditions, so as to find ways to better manage and treat them.

11 Nov 2011

N-acetylcysteine plus cortisone shows promise against acute alcoholic hepatitis

Acute alcoholic hepatitis is one of the most serious forms of alcoholic liver disease, affecting individuals with chronic excessive alcohol consumption, which generally equates to more than 50 grams of alcohol per day, over a period of more than three to six months. The disease is characterized by liver failure and acute jaundice (icterus), which may induce a coma through liver failure and an ensuing death rate of between 40-45% within the first six months.

11 Nov 2011

Link between physical activity, sedentary behavior and sleep in teens

Earlier research has had similar findings, but this is the first large, nationally representative study to connect physical activity, sedentary behavior and sleep in high school students, explained Kathryn Foti, M.P.H., a health scientist at the Centers for Disease Control and Prevention's (CDC) Division of Adolescent and School Health and lead author of the paper.

11 Nov 2011

Psychotherapy technique can help reduce dementia caregivers' stress

Family caregivers of people with dementia experience more burden and are at greater risk of developing depression than caregivers of people with a chronic illness. A new evidence review from the Netherlands finds that a psychotherapy technique called cognitive reframing can help reduce caregivers' stress when they are caring for loved ones with dementia.

11 Nov 2011

First large scale trial of acupuncture for prevention of xerostomia

When given alongside radiation therapy for head and neck cancer, acupuncture has shown for the first time to reduce the debilitating side effect of xerostomia, according to new research from The University of Texas MD Anderson Cancer Center and Fudan University Shanghai Cancer Center.

11 Nov 2011

New unsuspected role for nuclear receptor corepressor protein

By knocking out a key regulatory protein, scientists at the University of California, San Diego School of Medicine and the Ecole Polytechnique Federale de Lausanne (EPFL) in Switzerland dramatically boosted insulin sensitivity in lab mice, an achievement that opens a new door for drug development and the treatment of diabetes.

11 Nov 2011

Insights into potential causes of temporomandibular joint disorders

New findings about painful jaw problems that plague millions of Americans are leading to a better understanding of pain disorders.

11 Nov 2011

Classical DCs associated with protection against atherosclerosis

Atherosclerosis, commonly referred to as "hardening of the arteries," is a major risk factor for heart attack and stroke. The cause of atherosclerosis is not well understood but, for some time, chronic inflammatory immune responses have been implicated in driving disease pathology. Now, a new study, published online on November 10th by Cell Press from the journal Immunity, identifies a type of immune cell that is not associated with promoting disease, but with protection against atherosclerosis.

11 Nov 2011