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IP-K and Sanofi form new HBV research collaboration

One of the most common and serious infectious diseases, Hepatitis B, is to be targeted in a new collaborative venture between the internationally-renowned translational research institute, Institut Pasteur Korea (IP-K), and the Korean arm of the leading global healthcare company, Sanofi-Aventis Korea. The goal is to develop and validate a high throughput assay to screen IP-K's chemical libraries for novel compounds that can be developed as new drugs.

3 Nov 2011

Final results from Medivir's TMC435 phase IIb study on genotype-1 hepatitis C

Medivir AB, a research-based speciality pharmaceutical company focused on infectious diseases, today announces final results from the ASPIRE study.

3 Nov 2011

Broader screening for hypertrophic cardiomyopathy

Around one in 500 Swedes carry a genetic mutation which can cause sudden cardiac death. The diagnosis can lead to major lifestyle changes, but quality of life can be maintained with the right advice and support, reveals a new study from the Sahlgrenska Academy at the University of Gothenburg, Sweden.

2 Nov 2011

Towards a cure for chronic fatigue syndrome

Two doctors at Haukeland University Hospital have made great progress in their work to solve chronic fatigue syndrome (CFS). Trials cancer medicine has improved the health of two out of three CFS patients.

2 Nov 2011

Radiation therapy prior to HCT improves outcomes in older patients with hematologic malignancies

Older patients with advanced hematologic malignancies, such as leukemia and lymphoma, who received a conditioning regimen that included minimal-intensity radiation therapy prior to allogeneic hematopoietic cell transplantation had survival and progression-free survival outcomes suggesting that this treatment approach may be a viable option for older patients with these malignancies, according to a study in the November 2 issue of JAMA.

2 Nov 2011

Zalicus third quarter revenue increases to $2.4 million

Zalicus Inc. today reported financial results for the third quarter ended September 30, 2011.

2 Nov 2011

Hospitalized diabetic patients with acute kidney injury more likely to develop CKD

Findings from a recent University of Cincinnati (UC) and Cincinnati Department of Veterans Affairs (VA) Medical Center study show that multiple episodes of acute kidney injury during hospital stays for patients with diabetes are associated with a risk for developing chronic kidney disease.

2 Nov 2011

Solid organ transplant may increase risk of cancer

Patients who have received a solid organ transplant, such as kidney, liver, heart or lung, have an overall cancer risk that is double that of the general population, with an increased risk for many different types of malignancies, according to a study in the November 2 issue of JAMA.

2 Nov 2011

Age is no longer a barrier to allogeneic stem cell transplantation

Age alone no longer should be considered a defining factor when determining whether an older patient with blood cancer is a candidate for stem cell transplantation. That's the conclusion of the first study summarizing long-term outcomes from a series of prospective clinical trials of patients age 60 and over who were treated with the mini-transplant, a "kinder, gentler" form of allogeneic (donor cell) stem cell transplantation developed at Fred Hutchinson Cancer Research Center.

2 Nov 2011

Prostate cancer patients with bone metastases benefit from repeated 188Re-HEDP therapy

For prostate cancer patients with bone metastases, repeated administrations of radionuclide therapy with 188Re-HEDP are shown to improve overall survival rates and reduce pain, according to new research published in the November issue of The Journal of Nuclear Medicine.

2 Nov 2011

ADHD medications do not increase risk of heart attack in children, young adults

Attention Deficit Hyperactivity Disorder (ADHD) medications do not increase the risk for heart disease or heart attack in children and young adults, according to a Vanderbilt study of 1.2 million patients taking drugs including Ritalin, Adderall, Concerta and Strattera between 1998 and 2005.

2 Nov 2011

Targeted antibiotic safe and effective for irritable bowel syndrome

Among the most commonly used treatments for irritable bowel syndrome - which affects as many as 20 percent of the United States population - a targeted antibiotic was shown to be the safest in a new study by Cedars-Sinai researchers, based on an analysis of 26 large-scale clinical trials.

2 Nov 2011

First study to show how H. pylori toxin can spur apoptosis

Researchers report they have figured out how the cancer-causing bacterium Helicobacter pylori attacks a cell's energy infrastructure, sparking a series of events in the cell that ultimately lead it to self-destruct.

2 Nov 2011

Active partnership between patient and healthcare professionals can reduce hospital stay

Healthcare that implements a person-centred approach not only make care more efficient, but also yields more satisfied patients. A study carried out at the Sahlgrenska Academy at the University of Gothenburg, Sweden, shows that if there is an active partnership between the patient and healthcare professionals, the patient's hospital stay can be reduced by one-third.

2 Nov 2011

Ocrelizumab drug holds promise for multiple sclerosis

An experimental drug called Ocrelizumab has shown promise in a Phase 2 clinical trial involving 220 people with multiple sclerosis (MS), an often debilitating, chronic autoimmune disease that affects an increasing number of people in North America.

2 Nov 2011

Regular Yoga eases chronic back pain: Study

A new study found that those with chronic back pain might benefit from regular yoga. Three months of weekly yoga classes eased back pain more than the usual course of care — an informative back pain booklet said researchers. Even a year later, patients with chronic back pain who had participated in yoga classes reported less pain than those who hadn't been assigned the classes.

1 Nov 2011

ECMO and heart procedures performed as a bridge to lung transplantation

Surgeons at UK HealthCare recently became the first ever to perform two specific procedures together as a bridge to lung transplantation. Wanda Craig, of Lexington, Ky., is the first patient in history to receive these procedures, and at the age of 68, she is also the oldest living human to be bridged to transplant using an artificial lung device, also known as an extracorporeal membrane oxygenation (ECMO).

1 Nov 2011

New Mayo Clinic social network connects global community of esophageal cancer patients

In 2008, physicians at Mayo Clinic Florida led by Herbert Wolfsen, M.D., were looking for new ways to keep in touch with the large group of esophageal cancer patients cared for by him and other gastroenterologists and surgeons. Telephone calls, faxes and email had worked to create a network of patients but many now wanted interactive and remote access capability to share their experiences and challenges with this serious disease.

1 Nov 2011

Scientists identify genetic mutation that causes rare childhood disease

An international collaboration of scientists, including researchers at the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), a part of the National Institutes of Health, has identified a genetic mutation that causes a rare childhood disease characterized predominantly by inflammation and fat loss.

1 Nov 2011

Emotional and psychological traumas may contribute to adult IBS

The psychological and emotional traumas experienced over a lifetime--such as the death of a loved one, divorce, natural disaster, house fire or car accident, physical or mental abuse—may contribute to adult irritable bowel syndrome (IBS), according to the results of a study unveiled today at the American College of Gastroenterology's (ACG) 76th Annual Scientific meeting in Washington, DC.

1 Nov 2011