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Frog skin proteins could treat cancer, diabetes and stroke: New discovery

Scientists at Queen's University Belfast have discovered proteins in frog skins which could be used to treat cancer, diabetes, stroke and transplant patients by regulating the growth of blood vessels.

7 Jun 2011

Trifunctional antibody Catumaxomab triggers vaccination effect against cancer

TRION Pharma GmbH has announced that the results from two different studies demonstrate catumaxomab’s capacity to activate the immune system in a way that can otherwise only be achieved through vaccination. The data were obtained by two independent research teams using catumaxomab in malignant ascites and gastric cancer, respectively. The results were recently presented at the annual meeting of the American Society of Clinical Oncology (ASCO).

6 Jun 2011

FDA grants Pathway marketing clearance for JETSTREAM Navitus revascularization catheter for PVD

Pathway Medical Technologies, Inc, an innovator of endovascular treatments for peripheral vascular disease (PVD), announced today that the U.S. Food and Drug Administration (FDA) has granted the company 510(k) clearance to market JETSTREAM Navitus, an enhanced revascularization catheter for the treatment of PVD.

6 Jun 2011

Enrollment complete in Adolor's ADL5945 Phase 2 clinical study in opioid-induced constipation

Adolor Corporation today announced that it has completed enrollment in its Phase 2 clinical evaluation of ADL5945 in chronic, non-cancer pain patients with opioid-induced constipation (OIC).

6 Jun 2011

Amylin's metreleptin clinical study data on partial lipodystrophy presented at ENDO 2011

Amylin Pharmaceuticals, Inc. today announced results from a study that showed treatment with metreleptin, an investigational treatment that is an analog of the human hormone leptin, improved diabetes and lipid control in patients with partial lipodystrophy.

6 Jun 2011

Chiasma presents Octreolin pharmacology data from clinical studies at International Pituitary Congress

Chiasma, Inc., a privately held biopharma company, presented pharmacology results from clinical studies at the 12th International Pituitary Congress showing that Octreolin, a proprietary investigational new oral formulation of octreotide, demonstrated a consistent pharmacokinetic (PK) profile similar to that of subcutaneously injected octreotide acetate.

6 Jun 2011

United Therapeutics completes oral treprostinil Phase 3 trial on pulmonary arterial hypertension

United Therapeutics Corporation announced today the completion of its FREEDOM-M Phase 3 trial of treprostinil diethanolamine, an investigational sustained release oral formulation of treprostinil, a stable synthetic form of prostacyclin, in patients with pulmonary arterial hypertension (PAH).

6 Jun 2011

New study shows Bisphenol A exposure through diet has been underestimated

A new University of Missouri study shows that the exposure to the controversial chemical Bisphenol A (BPA) through diet has been underestimated by previous lab tests.

6 Jun 2011

Researchers discover a peptide that short circuits chronic pain pathway

Researchers at the Indiana University School of Medicine have discovered a peptide that short circuits a pathway for chronic pain. Unlike current treatments this peptide does not exhibit deleterious side effects such as reduced motor coordination, memory loss, or depression, according to an article in Nature Medicine posted online June 5, 2011.

6 Jun 2011

Smart bandage for chronic wounds

Melbourne researchers have come up with new “smart bandage” that changes colour depending on the temperature of the skin beneath, giving health professionals a powerful new tool for treating wounds and monitoring possible infections.

5 Jun 2011

Customizing targeted therapies to each tumor's molecular characteristics may effectively treat cancer

Customizing targeted therapies to each tumor's molecular characteristics, instead of a one-size-fits-all approach by tumor type, may be more effective for some types of cancer, according to research conducted by The University of Texas MD Anderson Cancer Center.

4 Jun 2011

Primary care providers treat hepatitis C patients effectively through Project ECHO model

Under a completely new way of providing health care, primary care clinicians in remote villages, prisons and poor urban neighborhoods who were trained to treat patients with hepatitis C achieved excellent results identical to those of specialists at a university medical center.

4 Jun 2011

GW researchers demonstrate Mta1 gene's role in survival of schistosomes

By using mice lacking a crucial gene that controls the process of chromatin remodeling of cytokines including those responsible for inflammation and comparing them to normal wild type mice with the gene, researchers at the George Washington University School of Medicine and Health Sciences have shown that the gene, Mta1, is essential for the parasite Schistosoma haematobium to establish a productive infection and survival in the host.

4 Jun 2011

Dendritic cells secrete signal molecule that contributes to pathogenesis of atherosclerosis

Atherosclerosis is the most common cause of cardiovascular disease, and results from chronic inflammation of arterial vessel walls. An international collaboration led by Professor Christian Weber of Ludwig-Maximilians-Universität (LMU) in Munich and Privatdozentin Alma Zernecke of Würzburg University now shows that dendritic cells stimulate this process by derailing a mechanism that normally acts as a brake on immune reactions.

4 Jun 2011

Five years after cancer treatment, many survivors still suffer symptoms

When people finish treatment for cancer, they want to bounce back to their former vital selves as quickly as possible. But a new Northwestern Medicine study -- one of the largest survivor studies ever conducted - shows many survivors still suffer moderate to severe problems with pain, fatigue, sleep, memory and concentration three to five years after treatment has ended.

4 Jun 2011

Henry Ford Hospital survey: ED physicians frustrated, tired of frequent users

Emergency department physicians are frustrated and burned out from treating patients who frequent the ED for their care, according to a Henry Ford Hospital survey of physicians from across the country.

4 Jun 2011

Combinations of mother's body size, placental size can predict heart disease in men in later life: Study

Researchers investigating the foetal origins of chronic disease have discovered that combinations of a mother's body size and the shape and size of her baby's placenta can predict heart disease in men in later life.

4 Jun 2011

Scientists demonstrate why B cells exposed to chronic HIV shut down, how they can be reactivated

Scientists at the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, have demonstrated why certain immune cells chronically exposed to HIV shut down, and how they can be reactivated.

4 Jun 2011

New discoveries about role of blood vessels in early lung development

A research team at The Saban Research Institute of Children's Hospital Los Angeles has made critical new discoveries about the role of blood vessels in guiding early lung development, especially in the essential, highly reproducible branching pattern of lung airways.

4 Jun 2011

Delayed treatment could prove effective in certain medical conditions

In today's fast-paced world, waiting — whether it's at the doctor's office, in line at the grocery store or for an Internet connection — is rarely considered a good thing.

3 Jun 2011

Chronic News and Research

Frog skin proteins could treat cancer, diabetes and stroke: New discovery

Trifunctional antibody Catumaxomab triggers vaccination effect against cancer

FDA grants Pathway marketing clearance for JETSTREAM Navitus revascularization catheter for PVD

Enrollment complete in Adolor's ADL5945 Phase 2 clinical study in opioid-induced constipation

Amylin's metreleptin clinical study data on partial lipodystrophy presented at ENDO 2011

Chiasma presents Octreolin pharmacology data from clinical studies at International Pituitary Congress

United Therapeutics completes oral treprostinil Phase 3 trial on pulmonary arterial hypertension

New study shows Bisphenol A exposure through diet has been underestimated

Researchers discover a peptide that short circuits chronic pain pathway

Smart bandage for chronic wounds

Customizing targeted therapies to each tumor's molecular characteristics may effectively treat cancer

Primary care providers treat hepatitis C patients effectively through Project ECHO model

GW researchers demonstrate Mta1 gene's role in survival of schistosomes

Dendritic cells secrete signal molecule that contributes to pathogenesis of atherosclerosis

Five years after cancer treatment, many survivors still suffer symptoms

Henry Ford Hospital survey: ED physicians frustrated, tired of frequent users

Combinations of mother's body size, placental size can predict heart disease in men in later life: Study

Scientists demonstrate why B cells exposed to chronic HIV shut down, how they can be reactivated

New discoveries about role of blood vessels in early lung development

Delayed treatment could prove effective in certain medical conditions

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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