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Patients with Sj-gren's syndrome have emotional problems, worse mental wellbeing

The results of a Dutch study of 300 patients demonstrated that 22% of patients with Sj-gren's syndrome were classified as clinically 'alexithymic' compared to 12% of healthy controls. Subsequent results of the study showed that higher levels of alexithymia were moderately correlated with worse mental wellbeing in both groups (Pearson's correlation (r) ≥ 0.32, p< 0.001), showing that there is a proven link between the two.

26 May 2011

Pharmasset, Bristol-Myers Squibb initiate PSI-7977 plus BMS-790052 combination Phase 2a trial in HCV

Pharmasset, Inc. announced today the initiation of a Phase 2a trial investigating the combination of Pharmasset's PSI-7977, a nucleotide polymerase inhibitor, and BMS-790052, Bristol-Myers Squibb Company's NS5A replication complex inhibitor, for the treatment of chronic hepatitis C.

26 May 2011

Mayoly-Spindler, ProteaBio complete MS1819 Phase I/IIA trial in malabsorption syndrome

ProteaBio Europe SAS, announced today that the company, in partnership with Mayoly-Spindler, has successfully completed a Phase I/IIA human clinical trial for their MS1819 recombinant Lipase.

26 May 2011

Studies find antibiotics overused for children with asthma, urinary tract infections

Two new studies led by researchers at the University of California, San Francisco have found some antibiotics may be overused for children with asthma and urinary tract infections.

26 May 2011

Patients with rheumatoid arthritis two times more likely to have concurrent COPD

Patients with rheumatoid arthritis are two times more likely to have concurrent chronic obstructive pulmonary disease than healthy controls -- an association which was sustained even when variables such as age, gender, smoking and obesity were controlled for, according to a study presented today at the EULAR 2011 Annual Congress.

26 May 2011

New Hypertension Management Program study results revealed at ASH scientific meeting

High blood pressure - the silent killer - is taking a hit from a new, ground-breaking treatment program from the Heart and Stroke Foundation of Ontario.

26 May 2011

Low vitamin D could account for link between obesity and cancer, heart disease, diabetes

Overweight or obese women with less-than-optimal levels of vitamin D who lose more than 15 percent of their body weight experience significant increases in circulating levels of this fat-soluble nutrient, according to a new study by researchers at Fred Hutchinson Cancer Research Center.

26 May 2011

Viewpoints: Sebelius, Orszag on Medicare costs; has the Minnesota GOP lost its way?

The right way is to strengthen it, closing coverage gaps while also bringing down costs by improving care and reducing waste and fraud. Medicare's trustees estimate that the new health care law has already added eight years to the life of the Medicare trust fund by doing just that. The president's fiscal framework would put the program on even more solid ground in the future.

26 May 2011

Scarcity of resources calls for equitable distribution system for novel HCV treatment

For many patients with the hepatitis C virus, direct antiviral agents (DAA) offer a potential cure for the disease. The Food and Drug Administration (FDA) has recently approved two new DAAs, telaprevir and boceprevir, and with that clinicians must now decide who should be the first to receive this treatment.

25 May 2011

First Edition: May 25, 2011

Kaiser Health News staff writer Phil Galewitz reports: "Most Americans oppose the House Republicans' plan to overhaul and slash funding of Medicaid, the state-federal program that covers 56 million low-income people, according to a poll being released today".

25 May 2011

Derma Sciences announces results of DSC127 Phase 2 trial in diabetic foot ulcers at 24-weeks

Derma Sciences, Inc., a medical device and pharmaceutical company focused on advanced wound care, today announced that in the follow-up portion of its Phase 2 clinical trial in patients with diabetic foot ulcers, the percentage of patients treated with the therapeutic dose of DSC127 with complete healing at 24 weeks following trial enrollment was 73% in the intent-to-treat population and 85% in the per-protocol population, a difference of 27 and 33 percentage points, respectively, compared with patients treated with placebo/standard of care.

25 May 2011

Obesity and diabetes rates continue to rise despite decline in consumption of sweeteners

A comprehensive review of research focusing on the debate between High Fructose Corn Syrup and other sweeteners presented today finds there is no evidence of any significant variation in the way the human body metabolizes HFCS as opposed to standard table sugar, or any difference in impact on risk factors for chronic disease.

25 May 2011

New findings from STELARA psoriasis clinical trial to be presented at 22nd World Congress of Dermatology

New findings to be presented from pooled analyses of the STELARA psoriasis clinical development program showed that the safety profile of STELARA and rates of adverse events remained consistent and stable over time in adults with moderate to severe plaque psoriasis receiving up to four years of treatment.

25 May 2011

Two Novartis ACZ885 Phase III trial data in severe gouty arthritis to be presented at EULAR 2011

Novartis announced results of two pivotal Phase III trials in patients with severe gouty arthritis, showing that ACZ885 provided superior pain relief and reduced the risk of suffering new attacks by up to 68% compared to an injectable steroid used to treat gouty arthritis attacks.

25 May 2011

Homeless people more likely to have family doctor if they possess health card

For every year a person is homeless, the odds of them having a family doctor drop by 9 per cent, according to a report by St. Michael's Hospital and Street Health.

25 May 2011

Biogen Idec launches educational forum, 'Women in MS'

Biogen Idec today announced the launch of "Women in MS," an educational initiative to address both the advantages and challenges female clinicians experience in treating patients living with multiple sclerosis.

25 May 2011

Leukemia protein plays a role in Alzheimer's disease

After decades of studying the pathological process that wipes out large volumes of memory, scientists at The Feinstein Institute for Medical Research discovered a molecule called c-Abl that has a known role in leukemia also has a hand in Alzheimer's disease.

25 May 2011

UCSD students study what happens when blood floods headward in microgravity

In space, the old movie slogan declares, "no one can hear you scream." On the other hand, you might look like it, with puffy face, swollen eyes and distended neck veins. This is what happens when, screaming or not, bodily fluids shift in the absence of gravity.

25 May 2011

New combination therapy eradicates acute lymphoblastic leukemia in children, older adults

In a significant breakthrough, investigators at Weill Cornell Medical College and the University of California, San Francisco, have been able to overcome resistance of a form of leukemia to targeted therapy, demonstrating complete eradication of the cancer in cell and animal studies.

25 May 2011

Vectra DA blood test may help predict patients' response to rheumatoid arthritis therapy

Crescendo Bioscience- today announced data indicating that Vectra- DA, a first-in-class multi-biomarker blood test used to assess rheumatoid arthritis disease activity, provides physicians with an objective measure which may help determine whether patients are responding to therapy.

25 May 2011

Chronic News and Research

Patients with Sj-gren's syndrome have emotional problems, worse mental wellbeing

Pharmasset, Bristol-Myers Squibb initiate PSI-7977 plus BMS-790052 combination Phase 2a trial in HCV

Mayoly-Spindler, ProteaBio complete MS1819 Phase I/IIA trial in malabsorption syndrome

Studies find antibiotics overused for children with asthma, urinary tract infections

Patients with rheumatoid arthritis two times more likely to have concurrent COPD

New Hypertension Management Program study results revealed at ASH scientific meeting

Low vitamin D could account for link between obesity and cancer, heart disease, diabetes

Viewpoints: Sebelius, Orszag on Medicare costs; has the Minnesota GOP lost its way?

Scarcity of resources calls for equitable distribution system for novel HCV treatment

First Edition: May 25, 2011

Derma Sciences announces results of DSC127 Phase 2 trial in diabetic foot ulcers at 24-weeks

Obesity and diabetes rates continue to rise despite decline in consumption of sweeteners

New findings from STELARA psoriasis clinical trial to be presented at 22nd World Congress of Dermatology

Two Novartis ACZ885 Phase III trial data in severe gouty arthritis to be presented at EULAR 2011

Homeless people more likely to have family doctor if they possess health card

Biogen Idec launches educational forum, 'Women in MS'

Leukemia protein plays a role in Alzheimer's disease

UCSD students study what happens when blood floods headward in microgravity

New combination therapy eradicates acute lymphoblastic leukemia in children, older adults

Vectra DA blood test may help predict patients' response to rheumatoid arthritis therapy

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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