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New study links vitamin D deficiency with deficits in altered lung structure and function

Previously linked to the severity of asthma and chronic obstructive pulmonary disease in humans, vitamin D deficiency has now been shown to alter lung structure and function in young mice. The new study, conducted by researchers in Australia, offers the first concrete evidence linking vitamin D deficiency with deficits in lung function and altered lung structure.

28 Jan 2011

EHSI examines business plans and product lines of OceanBASIS

Emerging Healthcare Solutions, Inc. is examining the business plans and product lines of German biotech firm OceanBASIS as part of the company's due diligence towards a potential profit sharing agreement.

28 Jan 2011

Phase II trial finds fostamatinib ineffective in RA patients not responsive to biologic agents

In a previous study, rheumatoid arthritis (RA) patients who failed to respond to methotrexate were shown to experience positive results with fostamatinib disodium (R788), an oral spleen tyrosine kinase (Syk) inhibitor that is thought to block immune cell signaling involved with bone and cartilage destruction. In the current study, RA patients who failed to respond to biologic agents were studied.

28 Jan 2011

Study identifies gaps in primary health care for seniors with multiple chronic conditions

The number of health care services seniors use is determined more by the number of chronic conditions they have than by their age, according to a new study from the Canadian Institute for Health Information.

28 Jan 2011

Magnetic nanoparticles for ovarian cancer treatment

A paper published in the January issue of the journal Nanomedicine could provide the foundation for a new ovarian cancer treatment option - one that would use an outside-the-body filtration device to remove a large portion of the free-floating cancer cells that often create secondary tumors.

28 Jan 2011

Discovery of aldose reductase enzyme can result in new therapies for asthma and COPD

Researchers have proved that a single "master switch" enzyme, known as aldose reductase, is key in producing excess mucous that clogs the airways of people with asthma and chronic obstructive pulmonary disease.

28 Jan 2011

Tobacco smoke exposure still a major cause for asthma attacks in kids: National Poll

Exposure to smokers is still a major cause of asthma attacks in kids, according to results of a poll released today by the C.S. Mott Children's Hospital National Poll on Children's Health.

28 Jan 2011

Early dental visit is important for good oral health in children

Good oral health is a key component of good overall health in children, which is why an early visit to the dentist is very important, says Temple University pediatric dentist Mark Helpin.

28 Jan 2011

Interferon-alpha associated with increased risk of atherosclerosis in patients with SLE

Researchers in China have demonstrated interferon-alpha (IFN-α) is associated with increased risk of atherosclerosis in patients with systemic lupus erythematosus (SLE). For the first time, IFN-α priming was shown to promote lipid uptake and foam cell formation—a crucial step in plaque build-up. This activation of the IFN signaling pathway may be linked to the premature atherosclerosis risk in SLE.

27 Jan 2011

Anaphylaxis through the eyes of the food-allergic child

New research shows young people who have experienced life-threatening anaphylactic shock from specific food exposures have significantly different views of the risks associated with their allergies based on their age and can benefit from discussing their perceptions of the safety of their school environment in improving their ability to cope.

27 Jan 2011

Baxter fourth quarter net income declines 26% to $423 million

Baxter International Inc. today announced its financial results for the fourth quarter of 2010, and provided its financial outlook for the first quarter and full-year 2011.

From Baxter International Inc. 27 Jan 2011

PHDcic, Aetna receive Health Service Journal award for programme to create systemic change in primary care

An innovative group of GPs in the West Midlands is proving that starting small can produce big changes — and their efforts are not going unnoticed. Pathfinder Healthcare Developments cic (PHDcic) together with Aetna Health Services UK (Aetna) have secured their latest award from the Health Service Journal for a programme that aims to create systemic change in primary care.

27 Jan 2011

Scientists discover new mechanism neurons use to fine-tune electrical output

Scientists in the Hotchkiss Brain Institute at the Faculty of Medicine, University of Calgary, have discovered a new mechanism that nerve cells (neurons) use to fine-tune their electrical output. The exciting discovery, published this week in the prestigious journal Nature Neuroscience, provides new insights about how the activity of the nervous system is regulated at the cellular level.

27 Jan 2011

Fibroblasts help 'recruit' immune cells for tumor growth

The most common connective tissue cell in animals is the fibroblast, which plays an important role in healing wounds. But Dr. Neta Erez of Tel Aviv University's Sackler Faculty of Medicine has now demonstrated that fibroblasts can also do a body great harm, helping to "recruit" immune cells for tumor growth.

27 Jan 2011

NQF endorses outcome measures to improve quality of care for people with mental illnesses

The National Quality Forum has endorsed outcome measures to assess the results and thereby improve the quality of care provided to people with mental illnesses. The 4 endorsed mental health measures focus on depression and patients' satisfaction during an inpatient psychiatric hospital stay.

27 Jan 2011

'Phenotype switching' helps bacteria lie dormant inside host cells and become a reservoir for relapsing infections

A new study into Staphylococcus aureus, the bacterium which is responsible for severe chronic infections worldwide, reveals how the bacteria have developed a strategy of hiding within host cells to escape the immune system as well as many antibacterial treatments. The research, published by EMBO Molecular Medicine, demonstrates how 'phenotype switching' enables bacteria to adapt to their environmental conditions, lie dormant inside host cells and become a reservoir for relapsing infections.

27 Jan 2011

Metanx promotes restoration of lost cutaneous sensation in Diabetic Neuropathy patients

PamLab L.L.C., developer and marketer of Metanx®, announced today that the results of a study to determine if nutritional management with Metanx® improves numbness in the feet of patients with Diabetic Neuropathy (DN) was published in the fourth quarter 2010 issue of Reviews in Neurological Diseases. The study demonstrated that Metanx®, a medical food available by prescription, promotes restoration of lost cutaneous sensation in DN patients.

27 Jan 2011

NIH study helps explain survival rate discrepancy between cardiac arrest in public and home

Cardiac arrests that can be treated by electric stimulation, also known as shockable arrests, were found at a higher frequency in public settings than in the home, according to a National Institutes of Health-funded study appearing in the Jan. 27 issue of the New England Journal of Medicine.

27 Jan 2011

Study: Removal of B lymphocytes can reverse aging process

Researchers at the Technion-Israel Institute of Technology have discovered a way to reverse the aging process by removing old B lymphocytes from old mice, and forcing the production of young, potent cells to replace them.

27 Jan 2011

QIAGEN announces formation of subsidiary in India

QIAGEN today announced the formation of its India subsidiary, QIAGEN India Pvt. Ltd., and the beginning of direct sales in the country. Until now, QIAGEN products have been sold in India through distributor partnerships.

From QIAGEN Manchester Limited 27 Jan 2011

Chronic News and Research

New study links vitamin D deficiency with deficits in altered lung structure and function

EHSI examines business plans and product lines of OceanBASIS

Phase II trial finds fostamatinib ineffective in RA patients not responsive to biologic agents

Study identifies gaps in primary health care for seniors with multiple chronic conditions

Magnetic nanoparticles for ovarian cancer treatment

Discovery of aldose reductase enzyme can result in new therapies for asthma and COPD

Tobacco smoke exposure still a major cause for asthma attacks in kids: National Poll

Early dental visit is important for good oral health in children

Interferon-alpha associated with increased risk of atherosclerosis in patients with SLE

Anaphylaxis through the eyes of the food-allergic child

Baxter fourth quarter net income declines 26% to $423 million

PHDcic, Aetna receive Health Service Journal award for programme to create systemic change in primary care

Scientists discover new mechanism neurons use to fine-tune electrical output

Fibroblasts help 'recruit' immune cells for tumor growth

NQF endorses outcome measures to improve quality of care for people with mental illnesses

'Phenotype switching' helps bacteria lie dormant inside host cells and become a reservoir for relapsing infections

Metanx promotes restoration of lost cutaneous sensation in Diabetic Neuropathy patients

NIH study helps explain survival rate discrepancy between cardiac arrest in public and home

Study: Removal of B lymphocytes can reverse aging process

QIAGEN announces formation of subsidiary in India

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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