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Bone marrow stem cell transplantation provides therapeutic benefit to patients with end-stage liver disease

Transplanting their own bone marrow-derived stem cells into 48 patients with end-stage liver disease resulted in therapeutic benefit to a high number of the patients, report researchers publishing in the current issue of Cell Transplantation. Yet, the mechanism by which the infusion of CD34+ stem cells improves liver function remains elusive, they say.

11 Jan 2011

Pain services severely inadequate: report

The Patients Association has urged the Government to create a clear care pathway for chronic pain services throughout the National Health Service. This came in after a survey of more than 4,000 patients revealed significant shortcomings in care.

11 Jan 2011

Lilly and Boehringer Ingelheim enter global agreement to develop and commercialize diabetes compounds

Eli Lilly and Company and Boehringer Ingelheim today announced a global agreement to jointly develop and commercialize a portfolio of diabetes compounds currently in mid- and late-stage development.

11 Jan 2011

New study on being medically prepared for natural disasters

Imagine having to evacuate your home quickly as 60 mph winds shatter your windows, water crawls under your front door and the electricity cuts leaving your house as dark as the inside of a coffee can. Would you be prepared? Now visualize being one of the 56 million Americans with a disability, such as wheelchair dependence, or one of the 133 million with a chronic disease, such as asthma.

11 Jan 2011

OraSure to introduce QuickFlu test for detection of type A and type B influenza

OraSure Technologies, announced today the impending launch of the OraSure QuickFlu Rapid Flu A+B Test, a U.S. Food and Drug and Administration approved in vitro rapid qualitative test for the detection of influenza type A and type B, including H1N1 viral infections.

11 Jan 2011

Emotional progress of patients treated with dialysis in the Basque Country Autonomous Community: Study

Patients who have to undergo dialysis see their lives inevitably affected by the treatment. Despite medical advances, the quality of life perceived by these kidney patients has improved very little, although it varies from person to person. Basing this as her starting point, Dr Begoña Ruiz de Alegría studied the emotional progress of patients treated with dialysis (hospitalised haemodialysis treatment and domiciliary peritoneal dialysis) in the Basque Country Autonomous Community.

11 Jan 2011

Vaccine Safety Conference affirms urgent need for methodologically sound vaccine science

An international meeting was held in Montego Bay, Jamaica Jan. 3-7, 2011 to discuss current vaccine science and policy safety concerns. Delegates from around the world included senior scientists and physicians, editors of scientific journals, experts in vaccine regulation, social science and health policy, consumer child health advocates, legal experts and members of the media.

11 Jan 2011

Cautionary note on measuring perceived pain in research

It is well known that pain is a highly subjective experience. We each have a pain threshold, but this can vary depending on distractions and mood. A paper in the International Journal of Behavioural and Healthcare Research offers a cautionary note on measuring perceived pain in research.

11 Jan 2011

WellApps releases Colonoscopy Prep Assistant

WellApps, LLC, developer of GI Monitor for Crohn's and Ulcerative Colitis, announced today the release of Colonoscopy Prep Assistant. During the portion of colonoscopy preparation when a patient ingests a liquid laxative, Colonoscopy Prep Assistant tracks the number of glasses completed and time between glasses, notifying the patient when it's time to drink their next glass. The app is available for free in iTunes and the Android Market.

11 Jan 2011

Pharmasset, Bristol-Myers Squibb collaborate for proof of concept study on chronic HCV

Bristol-Myers Squibb Company and Pharmasset announced today that the companies have entered into a clinical collaboration agreement to evaluate the utility of BMS-790052, Bristol-Myers Squibb's NS5A replication complex inhibitor, in combination with PSI-7977, Pharmasset's nucleotide polymerase inhibitor, for the treatment of chronic hepatitis C virus.

11 Jan 2011

New study finds nitric oxide gas has no therapeutic value in most premature babies

A new Johns Hopkins Children's Center study challenges the widespread practice of treating premature babies with nitric oxide gas to prevent lung problems, neurological damage and death.

11 Jan 2011

NPS completes treatment phase in GATTEX Phase 3 registration study in short bowel syndrome

NPS Pharmaceuticals, Inc. a specialty pharmaceutical company developing innovative therapeutics for rare gastrointestinal and endocrine disorders, today announced the completion of the 24-week treatment phase of the company's Phase 3 registration study of GATTEX® (teduglutide).

11 Jan 2011

Aid groups, U.N., U.S. discuss response to Haiti's earthquake as year anniversary approaches

On Friday, the Office of the U.N. Special Envoy to Haiti said that 63.6 percent of the aid international donors "pledged to Haiti in 2010 after a devastating earthquake nearly one year ago" has been disbursed, Deutsche Presse-Agentur/M&C reports (1/7).

11 Jan 2011

Adolor initiates second ADL5945 Phase 2 study in opioid-induced constipation

Adolor Corporation today announced that it is initiating a second Phase 2 study of ADL5945 in chronic non-cancer pain patients suffering from opioid-induced constipation (OIC).

10 Jan 2011

Civitas receives $20 million Series A financing

Civitas Therapeutics, Inc., a privately held biopharmaceutical company focused on developing transformative pulmonary delivery therapies, announced today that it has secured a $20 million Series A financing from founding investor, Longitude Capital, along with co-lead Canaan Partners. The proceeds of the financing will be primarily used to advance Civitas' lead program for treating patients with Parkinson's disease through clinical proof-of-concept.

10 Jan 2011

Omega-3 fatty acid may help protect against traumatic brain injury

Animal experiments suggest that taking the omega-3 fatty acid docosahexanoic acid (DHA) might offer a new way of protecting against traumatic brain injury (TBI), reports the February issue of Neurosurgery, official journal of the Congress of Neurological Surgeons.

10 Jan 2011

New mechanisms of resistance to chemotherapy among leukemia patients

The interplay between a major tumor-suppressing gene, a truncated chromosome and two sets of microRNAs provides a molecular basis for explaining the less aggressive form of chronic lymphocytic leukemia, an international team of researchers reports today in the Jan. 4 edition of the Journal of the American Medical Association.

10 Jan 2011

FDA, EMA accept boceprevir for expedited review

Merck, known as MSD outside the United States and Canada, announced today that regulatory applications for boceprevir, Merck's investigational oral hepatitis C virus (HCV) protease inhibitor, were submitted in 2010 and have been accepted for expedited review in both the U.S. and the European Union.

10 Jan 2011

U.S. District Court grants injunction for Sensipar patents

A U.S. District Court in Delaware today granted an injunction preventing Teva Pharmaceuticals USA, Inc., Teva Pharmaceuticals Industries Ltd., and Barr Laboratories, Inc. from commercializing generic versions of Amgen's Sensipar® (cinacalcet) until expiration of the drug's U.S. patents.

10 Jan 2011

Positive results form INX-189 Phase 1b trial against hepatitis C virus

Inhibitex, today reported positive preliminary interim safety and antiviral data from the first two monotherapy cohorts of its ongoing Phase 1b clinical trial of INX-189, an oral NS5b nucleotide inhibitor being developed to treat chronic infections caused by hepatitis C virus.

10 Jan 2011

Chronic News and Research

Bone marrow stem cell transplantation provides therapeutic benefit to patients with end-stage liver disease

Pain services severely inadequate: report

Lilly and Boehringer Ingelheim enter global agreement to develop and commercialize diabetes compounds

New study on being medically prepared for natural disasters

OraSure to introduce QuickFlu test for detection of type A and type B influenza

Emotional progress of patients treated with dialysis in the Basque Country Autonomous Community: Study

Vaccine Safety Conference affirms urgent need for methodologically sound vaccine science

Cautionary note on measuring perceived pain in research

WellApps releases Colonoscopy Prep Assistant

Pharmasset, Bristol-Myers Squibb collaborate for proof of concept study on chronic HCV

New study finds nitric oxide gas has no therapeutic value in most premature babies

NPS completes treatment phase in GATTEX Phase 3 registration study in short bowel syndrome

Aid groups, U.N., U.S. discuss response to Haiti's earthquake as year anniversary approaches

Adolor initiates second ADL5945 Phase 2 study in opioid-induced constipation

Civitas receives $20 million Series A financing

Omega-3 fatty acid may help protect against traumatic brain injury

New mechanisms of resistance to chemotherapy among leukemia patients

FDA, EMA accept boceprevir for expedited review

U.S. District Court grants injunction for Sensipar patents

Positive results form INX-189 Phase 1b trial against hepatitis C virus

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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