Angiotensin News and Research

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Angiotensin is an oligopeptide in the blood that causes vasoconstriction, increased blood pressure, and release of aldosterone from the adrenal cortex. It is a powerful dipsogen. It is derived from the precursor molecule angiotensinogen, a serum globulin produced in the liver. It plays an important role in the renin-angiotensin system.

High blood pressure treatment effective in reversing vascular damage

A hypertension medication called olmesartan medoxomil is effective in reversing the narrowing of the arteries that occurs in patients with high blood pressure, according to a new study.

16 Jun 2008

Kidney disease substantially worsens in a fourth of African Americans despite therapy for hypertension

The best available treatment for chronic kidney disease from high blood pressure did not keep the disease from substantially worsening in about a fourth of African-Americans studied, according to long-term results of a National Institutes of Health study published April 28, 2008, in the Archives of Internal Medicine.

5 May 2008

Study identifies new mechanism linking activation of key heart enzyme and oxidative stress

A study, led by University of Iowa researchers, reveals a new dimension for a key heart enzyme and sheds light on an important biological pathway involved in cell death in heart disease.

1 May 2008

Breakthrough compound could lead to new class of antihypertensive drugs

University of Florida researchers have identified a drug compound that dramatically lowers blood pressure, improves heart function and - in a remarkable finding - prevents damage to the heart and kidneys in rats with persistent hypertension

1 May 2008

Popular blood pressure drugs could hold the key to weight loss

A study by Australian scientists has indicated that some of the most commonly used blood pressure medications could help people lose weight and body fat and reduce the likelihood of them developing diabetes.

29 Apr 2008

Scientists discover way to increase metabolism for weight loss

Scientists from Melbourne's Howard Florey Institute have discovered a way to aid weight loss and reduce the likelihood of developing diabetes by manipulating fat cells to increase the body's metabolism.

28 Apr 2008

Mitochondrial dysfunction and redox signaling in atrial tachyarrhythmia

Researchers at the University Hospital of Magdeburg (Germany) have discovered that atrial tachycardia is associated with mitochondrial dysfunction and oxidative stress followed by the activation of the NF-kB signalling pathway with induction of NF-kB target gene expression in atrial tissue.

24 Apr 2008

Blood pressure drugs halt pancreatic cancer cell growth

Researchers at the Kimmel Cancer Center at Thomas Jefferson University in Philadelphia are inching closer to understanding how common blood pressure medications might help prevent the spread of pancreatic cancer.

15 Apr 2008

Blood pressure enzyme can have tumor-sensing role

By increasing production of a blood pressure-regulating enzyme in mice, researchers have found they can enhance the mouse immune system's ability to sense tumor growth.

8 Apr 2008

New blood pressure drug Micardis (Telmisartan) good at reducing deaths from heart attacks

An international team of researchers have found that a new blood pressure medication is as effective in reducing cardiovascular death, with fewer side effects than the current treatments offered.

1 Apr 2008

New blood pressure drug telmisartan has fewer side effects

A major Canadian-led global study has found that a new blood pressure medication is effective in reducing cardiovascular death, with fewer side effects than the current standard of care.

1 Apr 2008

Women are treated less frequently than men with statins, aspirin and beta-blockers

Women and men experience a similar prevalence of adverse drug reactions in the treatment of coronary artery disease; however, women are significantly less likely than their male counterparts to be treated with statins, aspirin, and beta-blockers according to a new study by researchers at Rush University Medical Center.

6 Mar 2008

Study explains preeclampsia develops

In a study of pregnant women, those with pregnancy-induced high blood pressure were found to have higher levels of a peptide that raises blood pressure in the pieces of tissue linking mother and fetus, according to researchers at Wake Forest University Baptist Medical Center.

11 Feb 2008

Enzyme released by mast cells in the lungs could be a new target for asthma

An enzyme released by mast cells in the lungs appears to play a key role in the tightening of airways that is a hallmark of asthma pointing to a potential new target for treatment against the illness.

4 Feb 2008

Lungs' mast cells could provide new treatment target for asthma, other respiratory disease

30 Jan 2008

New target found for asthma

An enzyme released by mast cells in the lungs appears to play a key role in the tightening of airways that is a hallmark of asthma -- pointing to a potential new target for treatment against the illness.

29 Jan 2008

Evidence strongly supports diuretics as initial metabolic syndrome therapy, especially in black patients

New research shows that in people with high blood pressure as part of metabolic syndrome, a cluster of conditions that increases the risk for heart disease, diuretics offer greater protection against cardiovascular disease, including heart failure, and are at least as effective for lowering blood pressure as newer, more expensive medications.

28 Jan 2008

Gene variations associated with effectiveness of blood pressure medications

Patients with hypertension and certain gene variations experienced varying results with some blood pressure medications, suggesting matching a patient's genotype with certain hypertension medications could result in more favorable outcomes, according to a study in the January 23 issue of JAMA: The Journal of the American Medical Association.

23 Jan 2008

Study proves the co-pay connection in chronic disease

As 2008 begins, millions of Americans are having to dig deeper into their own pockets every time they refill a prescription or see a doctor.

9 Jan 2008

Experimental IT to reduce medication errors under study

Medication errors are one of the most serious problems occurring in doctor's offices and out-patient clinics, and older persons with chronic conditions are the most vulnerable.

4 Jan 2008