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Specific brain abnormalities linked to motor neuron disease in athletes with head trauma

Professional athletes with repetitive head trauma and possibly others with a history of head injuries many years previously may be prone the development of a motor neuron disease similar to amyotrophic lateral sclerosis (ALS or "Lou Gehrig's disease"), reports a study in the September Journal of Neuropathology & Experimental Neurology, official journal of the American Association of Neuropathologists, Inc.

18 Aug 2010

Midatech Group, MonoSol Rx file patent to enable commercialization of drug delivery technology

Midatech Group Ltd., a global leader for the design, development, synthesis and manufacture of nanomedicines, and MonoSol Rx, the leader in developing and manufacturing pharmaceutical films based on its proprietary PharmFilm drug delivery technology, today announced the filing of a provisional US patent application for "Nanoparticle Film Delivery Systems." The applications submitted to the United States Patent and Trademark Office (USPTO) relate to therapeutic uses of nanoparticle-based proteins and peptides delivered in pharmaceutical films.

18 Aug 2010

HDVI's Medical Records Collection and Analysis system integrated with DST Health Solutions' CareAnalyzer

DST Health Solutions, LLC, today announced a business alliance with Health Data Vision, Inc. to integrate HDVI's Medical Records Collection and Analysis (MRCS) system with DST Health Solutions' CareAnalyzer® solution. CareAnalyzer is a comprehensive analytics software suite that combines elements of patient risk, care opportunities and provider performance. The solution is designed to help health plans improve care management and meet reporting requirements for the Healthcare Effectiveness Data and Information Set (HEDIS®).

18 Aug 2010

Genome-wide study identifies key genetic variant associated with nonalcoholic fatty liver disease

Researchers at Massachusetts General Hospital found that patients with nonalcoholic fatty liver disease (NAFLD) who carry an allele of the PNPLA3 gene have an increased risk of developing advanced disease, including nonalcoholic steatohepatitis (NASH), fibrosis, and cirrhosis. A second study supported by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) validates these findings and further concludes that in pediatric patients, the same allele is associated with earlier disease presentation.

18 Aug 2010

Long-term entecavir therapy suppresses HBV DNA, normalizes ALT and improves liver histology

Researchers from this international study found that patients with chronic hepatitis B virus (HBV) infection who received at least 3 years of cumulative entecavir (antiviral) therapy achieved substantial histologic improvement and regression of fibrosis or cirrhosis. Full details of the study appear in the September issue of Hepatology, a journal published by Wiley-Blackwell on behalf of the American Association for the Study of Liver Diseases (AASLD).

18 Aug 2010

Study finds black patients receive fewer opoid medications than whites

Black patients are prescribed fewer pain medications than whites and few women receive medications strong enough to manage their chronic pain, according to a study in the August issue of Journal of Pain.University of Michigan Health System researchers studied nearly 200 patients with chronic pain who sought help from a specialty pain center. Researchers analyzed the number and potency of medicines they were already taking and the adequacy of pain management.

18 Aug 2010

Researcher identifies immune system's ability to protect body against lung cancer

A Michigan State University researcher is analyzing the immune system's own ability to protect the body against lung cancer.The results of the work by Alison Bauer, an assistant professor of pathobiology and diagnostic investigation in the College of Veterinary Medicine, are expected to provide new approaches to prevent, identify and treat lung cancer.

18 Aug 2010

Cancer is the world's top 'economic killer,' report finds

The Associated Press: "Cancer is the world's top 'economic killer' as well as its likely leading cause of death, the American Cancer Society contends in a new report it will present at a global cancer conference in China this week. Cancer costs more in productivity and lost life than AIDS, malaria, the flu and other diseases that spread person-to-person, the report concludes.

18 Aug 2010

Long-term Entecavir therapy reverses fibrosis and cirrhosis in chronic hepatitis B patients

17 Aug 2010

Research confirms genetic link to advanced fatty liver disease

17 Aug 2010

Chronix Biomedical expands biomarker development capabilities with installation of DNA mass sequencer

Chronix Biomedical today reported that it has significantly expanded and accelerated its biomarker development capabilities with the installation of Germany's first state-of-the-art high-throughput DNA mass sequencer at the University of Göttingen, Chronix's long-time collaborator. Chronix is developing disease-specific biomarkers based on DNA fragments that are released into the bloodstream by damaged and dying (apoptotic) cells.

17 Aug 2010

ImPACKD, The Kidney Foundation of Canada launch online resource for CKD patients

Before today, millions of Canadians living with chronic kidney disease did not have a strong online advocacy presence. Improving Patient Advocacy in Chronic Kidney Disease and The Kidney Foundation of Canada are now joining forces to provide an effective resource. Together, they are launching www.impackd.ca, a microsite of www.kidney.ca that is specifically designed for Canadians affected by chronic kidney disease.

17 Aug 2010

Pisgah Labs receives Notice of Allowance for new patent relating to thyroid hormone drugs

Today, Pisgah Labs, Inc. received a Notice of Allowance from the United States Patent and Trademark office for an important new technology patent addressing global stability problems of thyroid hormone drugs.

17 Aug 2010

Xenon Pharmaceuticals commences phase 2 clinical trial of XEN402 therapy for PHN

Xenon Pharmaceuticals Inc. announced today that it has initiated a phase 2 clinical trial evaluating its novel topical XEN402 therapy for the treatment of PHN.

17 Aug 2010

Discovery can lead to new class of drugs for chronic pain treatment

Researchers have made a discovery that could lead to a brand new class of drugs to treat chronic pain caused by inflammatory conditions such as arthritis and back pain without numbing the whole body.

17 Aug 2010

Employers can play key role in promoting better health: Report

As the U.S. continues to struggle with both cost and quality issues in an evolving health care system, employers can play a key role in promoting better health and more efficient use of resources, The Health Project reported this week.

17 Aug 2010

Deconstruction of biomedical research on pain will improve diagnosis, treatment of chronic pain sufferers

Is the science of diagnosing pain causing a number of pain sufferers to defend their honor? Research out of the University of Cincinnati is examining the diagnosis of pain that evades scientific testing, and the additional emotional suffering that can result for the patient.

17 Aug 2010

Human adult stem cells can regenerate damaged heart tissue: Research

Mayo Clinic investigators, with Belgian collaborators, have demonstrated that rationally "guided" human adult stem cells can effectively heal, repair and regenerate damaged heart tissue. The findings called "landmark work" in an accompanying editorial appear in today's Journal of the American College of Cardiology.

17 Aug 2010

High exposure to estrogens may cause gall bladder cancer: Research

A very aggressive disease with a poor prognosis, gallbladder cancer may be connected to higher exposure to estrogens, according to a group of researchers at the University of Houston (UH). Dr. Jan--ke Gustafsson, Robert A. Welch Professor in UH's biology and biochemistry department, described his team's findings in a paper titled "Estrogen-dependent gallbladder carcinogenesis in LXRβ-/- female mice" appearing in a recent issue of the journal Proceedings of the National Academy of Sciences, one of the world's most-cited multidisciplinary scientific serials.

17 Aug 2010

Researchers find link between chronic inflammation and cancer

Virginia Commonwealth University Massey Cancer Center researchers have uncovered a new link between chronic inflammation and cancer. Although cancers do not always cause inflammation, chronic inflammation is known to help tumor cells grow.

17 Aug 2010

Chronic News and Research

Specific brain abnormalities linked to motor neuron disease in athletes with head trauma

Midatech Group, MonoSol Rx file patent to enable commercialization of drug delivery technology

HDVI's Medical Records Collection and Analysis system integrated with DST Health Solutions' CareAnalyzer

Genome-wide study identifies key genetic variant associated with nonalcoholic fatty liver disease

Long-term entecavir therapy suppresses HBV DNA, normalizes ALT and improves liver histology

Study finds black patients receive fewer opoid medications than whites

Researcher identifies immune system's ability to protect body against lung cancer

Cancer is the world's top 'economic killer,' report finds

Long-term Entecavir therapy reverses fibrosis and cirrhosis in chronic hepatitis B patients

Research confirms genetic link to advanced fatty liver disease

Chronix Biomedical expands biomarker development capabilities with installation of DNA mass sequencer

ImPACKD, The Kidney Foundation of Canada launch online resource for CKD patients

Pisgah Labs receives Notice of Allowance for new patent relating to thyroid hormone drugs

Xenon Pharmaceuticals commences phase 2 clinical trial of XEN402 therapy for PHN

Discovery can lead to new class of drugs for chronic pain treatment

Employers can play key role in promoting better health: Report

Deconstruction of biomedical research on pain will improve diagnosis, treatment of chronic pain sufferers

Human adult stem cells can regenerate damaged heart tissue: Research

High exposure to estrogens may cause gall bladder cancer: Research

Researchers find link between chronic inflammation and cancer

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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