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Study provides insight into evolution of amyloid-β oligomer with temporary salt crystals

Alzheimer's disease is the leading cause of dementia worldwide and a major cause of disability. Now, researchers at Osaka University and Hokkaido University have shown that repeated precipitation-dissolution events of salt crystals do occur even at low salt concentrations in nanoscales, and that it can accelerate the aggregation of the neurotoxic amyloid-β peptides implicated in its pathogenesis.

27 Jul 2020

Livestock expansion and biodiversity loss are positively related to global pandemics

The growth of global livestock farming is a threat to our biodiversity and also increases the health risks to both humans and domesticated animals.

24 Jul 2020

UB study validates a novel pharmacological target for Alzheimer’s disease

A UB study published in the journal Neurotherapeutics has validated a new pharmacological target for Alzheimer's disease.

24 Jul 2020

New model may explain why certain cancer cells are resistant to therapy

Cancer's knack for developing resistance to chemotherapy has long been a major obstacle to achieving lasting remissions or cures.

24 Jul 2020

Epigenomic modifications play key role in the development of lung tumors

As cancer cells evolve, many of their genes become overactive while others are turned down. These genetic changes can help tumors grow out of control and become more aggressive, adapt to changing conditions, and eventually lead the tumor to metastasize and spread elsewhere in the body.

23 Jul 2020

Study shows interferons do not induce the expression of SARS-CoV-2 cell entry receptor

In a new bioRxiv study, authors identified a isoform of ACE2 (designated as deltaACE2 or dACE2) receptor, shown to be induced in various human cell types.

23 Jul 2020

White blood cells and their role in the brain

Researchers have found that the brain has specific immune cells that help in normal brain development and play a role in certain neurological diseases.

23 Jul 2020

JRC releases 2020 estimates on cancer burden in the EU

Today, the European Commission Joint Research Centre released the 2020 estimates on the burden of cancer in the EU. Female breast cancer is still estimated to be the most commonly diagnosed cancer.

23 Jul 2020

Findings could help design vaccines against coronavirus

Scientists investigating the evolution of the virus that causes Covid19 say that its mutation seems to be directed by human proteins that degrade it, but natural selection of the virus enables it to bounce back. The findings could help in the design of vaccines against the virus.

23 Jul 2020

Researchers discover how infectious bacteria can produce genetic variants among siblings

A research team from the University of Tübingen and the German Center for Infection Research is investigating how pathogens influence the immune response of their host with genetic variation.

22 Jul 2020

Study points to an important role for white blood cells in brain development

Whether white blood cells can be found in the brain has been controversial, and what they might be doing used to be complete mystery.

22 Jul 2020

Study suggests new ways to fight aggressive brain cancer

A mouse model of glioblastoma, an aggressive type of cancer that can occur in the brain, suggests that this recalcitrant cancer originates from a pool of stem cells that can be a significant distance away from the resulting tumors.

22 Jul 2020

Proximity of mutated cells guides the initiation of tumor

Scientists have revealed a key factor that influences whether malignant cells will grow to form a tumor, in a new study published today in eLife.

21 Jul 2020

Chronic inflammation associated with IBD disrupts tissue structure of the colon, study finds

In a new study, researchers have compared diseased colon with healthy tissue to better understand how inflammatory bowel disease (IBD) is linked to an increased risk of colorectal cancers, at a molecular level.

21 Jul 2020

Farming landscapes can provide habitats for biodiversity

Over 360 scientists from 42 countries - led by the University of Göttingen and Westlake University China - call for transition of food production systems to agroecological principles.

21 Jul 2020

Harvard scientists uncover the real reason behind goosebumps

If you've ever wondered why we get goosebumps, you're in good company -- so did Charles Darwin, who mused about them in his writings on evolution.

20 Jul 2020

Mutant zebrafish opens a window into evolutionary history of human spine

A chance mutation that led to spinal defects in a zebrafish has opened a little window into our own fishy past.

20 Jul 2020

Sphere Fluidics and Heriot-Watt University collaborate to develop next generation droplet generator instrumentation

Sphere Fluidics, a company developing single cell analysis systems underpinned by its patented picodroplet technology, and Heriot-Watt University, a specialist, pioneering Scottish University, today announced they have been awarded a Knowledge Transfer Partnership (KTP) grant from Innovate UK, the UK’s innovation agency.

From Fluidic Sciences and Sphere Bio 20 Jul 2020

Hybrid fungus involved in lung infections discovered

Aspergillus latus, a species of fungus previously found only in soil or plants, has been found for the first time in a hospital environment by an international group of researchers.

19 Jul 2020

Groundbreaking technology could enhance therapeutic efficiency of nanomedicines

Researchers from the Moscow Institute of Physics and Technology and their colleagues from Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry and Prokhorov General Physics Institute of the Russian Academy of Sciences have developed a breakthrough technology to resolve a key problem that has prevented the introduction of novel drugs into clinical practice for decades.

17 Jul 2020