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Review sheds light on current therapeutic targets of miRNA-associated chemoresistance in EOC

Epithelial ovarian cancer (EOC) is the most lethal disease among gynecologic malignancies. Patients with an advanced disease often relapse due to the development of chemoresistance. Chemotherapy failure is a consequence of acquired drug resistance which may potentially be due to multiple mechanisms including miRNA-mediated gene regulation.

17 Jun 2016

Legions of immune cells play complex role to destroy Legionella bacteria

Immunologists and microbiologists from the University of Melbourne's Bio21 Molecular Science and Biotechnology Institute and the Peter Doherty Institute for Infection and Immunity - a joint venture between the University of Melbourne and Royal Melbourne Hospital - have led a study that defined a new cell type responsible for turning the attack back on the bacteria.

17 Jun 2016

Seven-day opening of doctor surgeries reduces weekend hospital emergencies by 18%

The UK Government's pilot of seven-day opening of doctor surgeries has significantly reduced weekend emergency hospital visits, hospital admissions and ambulance call-outs, new University of Sussex research has found.

17 Jun 2016

Researcher aims to develop easy-to-use, inexpensive sperm sorting devices to help infertile couples

The competition is fierce and only the strongest survive the obstacle course within the female reproductive tract. Of the millions of sperm that enter the vagina, only about 10 or so make it to the oocyte or egg, demonstrating how rigorous the natural sperm selection process really is.

17 Jun 2016

Elevated levels of CXCL10 protein could help diagnose cGvHD in blood, bone marrow transplant patients

A new study published today in the journal Blood has identified a protein that could diagnose chronic graft-versus-host disease (cGvHD), a serious, long-term complication that affects some patients after a blood and bone marrow transplant.

17 Jun 2016

New collaborative research program connects canine and human cancers

A new collaborative research program pairs oncologists who treat childhood and adult sarcomas with veterinarians who manage the same cancers in canine patients.

17 Jun 2016

Black children more likely to have postsurgical complications after urologic surgery

Black children who undergo urologic surgery are more likely than white children to have postsurgical complications and hospital-acquired infections 30 days after the surgery.

17 Jun 2016

Caribbean, African-born women more likely to be admitted at ICU during delivery

Women born in the Caribbean or Africa are two times more likely to be admitted to an intensive care unit at the time of their delivery than Canadian-born women, a new study has found.

17 Jun 2016

Sleep-disordered breathing increases cardiovascular risk in ACS patients

Sleep-disordered breathing is an important risk factor for major adverse cardiocerebrovascular events among patients with acute coronary syndromes, Japanese research shows.

17 Jun 2016

Natural molecule NAC could benefit patients with Parkinson's disease

The natural molecule, n-acetylcysteine (NAC), with strong antioxidant effects, shows potential benefit as part of the management for patients with Parkinson's disease, according to a study published today in the journal PLOS ONE.

17 Jun 2016

Epilepsy in immediate family member may increase person’s chances of being diagnosed with autism

Having a first-degree relative with epilepsy may increase a person's risk of being diagnosed with autism, according to a study published in the June 15, 2016, online issue of Neurology, the medical journal of the American Academy of Neurology.

17 Jun 2016

Resolution to train public, professional responders in bleeding control techniques receives overwhelming support

Yesterday the American Medical Association's House of Delegates approved a resolution introduced by the American College of Surgeons and other medical societies to train more professional first responders (i.e., police and firefighters) and civilians as immediate responders in the essential techniques of bleeding control and to place bleeding control kits (containing tourniquets, pressure bandages, hemostatic dressings, and gloves) with first responders.

16 Jun 2016

Study sheds new light on how overeating may lead to more eating

Research is finally beginning to shed light on some of the reasons that extra weight is difficult to shed permanently. Now, a new study has uncovered another method by which the gut senses how much food a person eats and relays that to the brain.

16 Jun 2016

Penn researchers explore possibilities to improve outcomes in low flow AS patients treated with TAVR

Aortic stenosis (AS), the narrowing of the aortic valve in the heart which causes restricted blood flow, is one of the most common and serious valve disease problems. For patients with one type of AS - low flow - transcatheter aortic valve replacement (TAVR), a minimally invasive procedure which corrects the damaged aortic valve, is often the best option for restoring the heart's normal pumping function.

16 Jun 2016

New superbug test developed by TGen-NAU receives Australian patent

Antibiotic-resistant infections should be easier to detect, and hospitals could become safer, thanks to a technology developed by the Translational Genomics Research Institute and Northern Arizona University, and protected under a patent issued by Australia.

16 Jun 2016

Study shows for-profit hospices have persistently high rates of hospitalization

Patients who were asked where they wanted to die upon entering hospice had lower rates of hospitalization at the end of life, as did those in hospices that monitored symptoms more frequently, according to a new study led by researchers at the Icahn School of Medicine at Mount Sinai.

16 Jun 2016

Targeted intervention helps improve effectiveness of newborn hearing screening programs

Researchers at Cincinnati Children's Hospital Medical Center found that targeted intervention helps improve follow-up rates by more than 70 percent for newborns who fail initial hearing screenings at birth hospitals.

16 Jun 2016

Surgical treatment more effective than medical therapy for treating severely obese adolescents

An analysis of the results of a study of bariatric surgery and a separate trial of medical therapy in treating type 2 diabetes in teenagers with severe obesity shows that after two years of treatment, body mass index (BMI) and HbA1c, a measure of blood sugar control, are both significantly better with surgery.

16 Jun 2016

'Nonserious' side effects may lead to antiplatelet discontinuation

Most adverse events that lead patients to discontinue antiplatelet drugs are not rated as serious by clinical trial criteria, shows analysis of the PEGASUS-TIMI 54 trial.

16 Jun 2016

Empagliflozin offers long-term renal protection in Type 2 diabetes

The sodium-glucose cotransporter 2 inhibitor empagliflozin slows renal progression and averts clinical events, shows further analysis of the EMPA-REG OUTCOME trial.

16 Jun 2016

Hospital News and Research

Review sheds light on current therapeutic targets of miRNA-associated chemoresistance in EOC

Legions of immune cells play complex role to destroy Legionella bacteria

Seven-day opening of doctor surgeries reduces weekend hospital emergencies by 18%

Researcher aims to develop easy-to-use, inexpensive sperm sorting devices to help infertile couples

Elevated levels of CXCL10 protein could help diagnose cGvHD in blood, bone marrow transplant patients

New collaborative research program connects canine and human cancers

Black children more likely to have postsurgical complications after urologic surgery

Caribbean, African-born women more likely to be admitted at ICU during delivery

Sleep-disordered breathing increases cardiovascular risk in ACS patients

Natural molecule NAC could benefit patients with Parkinson's disease

Epilepsy in immediate family member may increase person’s chances of being diagnosed with autism

Resolution to train public, professional responders in bleeding control techniques receives overwhelming support

Study sheds new light on how overeating may lead to more eating

Penn researchers explore possibilities to improve outcomes in low flow AS patients treated with TAVR

New superbug test developed by TGen-NAU receives Australian patent

Study shows for-profit hospices have persistently high rates of hospitalization

Targeted intervention helps improve effectiveness of newborn hearing screening programs

Surgical treatment more effective than medical therapy for treating severely obese adolescents

'Nonserious' side effects may lead to antiplatelet discontinuation

Empagliflozin offers long-term renal protection in Type 2 diabetes

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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