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Accumulation of fat droplets makes cancer cells more aggressive

It has been established that not all cancer cells are equally aggressive - most can be neutralised with radiation and chemotherapy. Researchers at Lund University in Sweden have now discovered that some cancer cells can accumulate fat droplets, which appear to make them more aggressive and increase their ability to spread.

3 Jun 2016

Overweight adolescents can increase physical activity by using their built environment

A program encouraging overweight or obese adolescents to increase their physical activity through use of their everyday environment, rather than organized classes or sports programs, produced significant increases in participants' daily physical activity that were sustained for at least three to four months.

3 Jun 2016

Researchers detect vascular matrix stiffening during early stages of pulmonary hypertension

Pulmonary hypertension is an abnormal elevation of pressure in the pulmonary circulation that results in stress on the heart and remodeling of blood vessels in the lung.

3 Jun 2016

Scientists use new technique to repair fibrotic liver cells within the organ

Advances in stem cell research have made it possible to convert patients' skin cells into heart cells, kidney cells, liver cells and more in the lab dish, giving researchers hope that one day such cells could replace organ transplantation for patients with organ failure.

3 Jun 2016

Immunotherapy with experimental monoclonal antibody could reduce neuroblastoma tumors

Neuroblastoma tumors shrank, some dramatically, in 80 percent of newly diagnosed, young, high-risk patients enrolled in a Phase II clinical trial that included an experimental monoclonal antibody. The immunotherapy agent was produced on the St. Jude Children's Research Hospital campus where the study is still underway.

3 Jun 2016

Common genetic variant in HO-1 gene linked to AKI risk following cardiac surgery

Testing for a common genetic variant may help reveal which patients face an increased risk of developing kidney damage following heart surgery. The findings, which come from a study appearing in an upcoming issue of the Journal of the American Society of Nephrology, may help investigators develop therapeutic strategies to mitigate this damage.

3 Jun 2016

Researchers developing more accessible way to monitor brain health

Simon Fraser University researchers hope that a brain vital-sign test becomes as routine during a doctor's check-up as taking a blood pressure or heart rate measurement.

3 Jun 2016

Retroviral replicating vector can extend lives of brain cancer patients

Doctors at UCLA, Cleveland Clinic, University of California San Diego School of Medicine and additional institutions have achieved a milestone in the development of a treatment for people with recurrent glioblastoma, the most common and aggressive form of brain cancer, by successfully demonstrating a modified virus that can extend the lives of patients with the disease.

2 Jun 2016

Specific commercial red algae could help combat food allergies

Seaweed has long been a staple food in many Asian countries and has recently caught on as a snack food in America as a healthful alternative to chips. The edible algae that fall in the category of seaweed are low-calorie and packed with nutrients

2 Jun 2016

Some women with ovarian cancer do not receive beneficial surgical treatment, study finds

Nearly 20 percent of women with ovarian cancer do not undergo surgery, despite it being a standard part of treatment recommendations, according to new research from the Perelman School of Medicine at the University of Pennsylvania.

2 Jun 2016

Large national effort shows promise in reducing both catheter use and UTI rates

Right now, about one in five hospital patients has a catheter collecting their urine - and putting them at risk of a painful and potentially dangerous urinary tract infection, or UTI.

2 Jun 2016

Nivolumab and ipilimumab combination could lead to effective treatment options for SCLC patients

Small cell lung cancer (SCLC) represents approximately 14 percent of all types of lung cancer. Many patients with SCLC respond to initial chemotherapy; however, they eventually relapse and develop progressive disease that has no effective treatment options.

2 Jun 2016

Severe obesity may contribute to infection risk after bypass surgery

Severely obese patients who undergo a coronary artery bypass are more likely to develop an infection after surgery and stay in hospital longer, compared with people of normal weight, according to a study published in the Journal of the American Heart Association.

2 Jun 2016

PAN-EX supports neoadjuvant chemotherapy in high-risk rectal cancer

Patients with high-risk, locally advanced rectal cancer could benefit from neoadjuvant chemotherapy before undergoing chemoradiotherapy, suggest the results of a pooled analysis.

2 Jun 2016

BRCA gene mutations raise risk of breast, ovarian and other cancers

BRCA Share, a public-private BRCA gene datashare initiative, today announced the public release of a large collection of new data on genetic variants in the BRCA1 and BRCA2 genes.

From Quest Diagnostics 2 Jun 2016

Supportive leadership can help overcome language barriers to educate new parents about SBS/AHT

Language is a key obstacle to meeting guidelines for educating parents of newborns about "shaken baby syndrome"—also called abusive head trauma (SBS/AHT), reports a study in the Journal of Trauma Nursing, official publication of the Society of Trauma Nurses. The journal is published by Wolters Kluwer.

2 Jun 2016

Scientists use optogenetics technique to increase memory in mice brain

Raül Andero Galí, one of the heads of the "Neurobiology of Stress and Addiction" research group at the Institut de Neurociències of the Universitat Autònoma de Barcelona and researcher at Harvard University, published an article in which, for the first time in Spain, optogenetics was used to increase memory.

2 Jun 2016

New IRAP inhibitors may hold promise for improving cognitive functions in animal models

Researchers have discovered three new inhibitors of insulin-regulated aminopeptidase (IRAP), compounds shown to improve cognitive functions in animal models of human disorders.

2 Jun 2016

Deployed military soldiers three times more likely to suffer non-combat musculoskeletal injuries

Since September 11, 2001, an estimated 60,000 U.S. military service members have been injured in combat during the Afghanistan and Iraq wars. Nearly 45,000 of all combat injuries are caused by improvised explosive devices, also known as IEDs.

2 Jun 2016

Multiple cell and gene therapies can enhance cardiac function in mice modeled with MI

Researchers at the University of Utah compared the therapeutic potential of umbilical cord-derived sub-epithelial cells (UC-SECs), bone marrow-derived mesenchymal stem cells (BM-MSCs) and induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) -- all derived from human tissue -- along with genes (S100a1 and SDF-1a) and growth factor (VEGF165) to evaluate how injected biologics might enhance cardiac function in mice modeled with myocardial infarction (MI; commonly referred to as heart attack).

2 Jun 2016

Hospital News and Research

Accumulation of fat droplets makes cancer cells more aggressive

Overweight adolescents can increase physical activity by using their built environment

Researchers detect vascular matrix stiffening during early stages of pulmonary hypertension

Scientists use new technique to repair fibrotic liver cells within the organ

Immunotherapy with experimental monoclonal antibody could reduce neuroblastoma tumors

Common genetic variant in HO-1 gene linked to AKI risk following cardiac surgery

Researchers developing more accessible way to monitor brain health

Retroviral replicating vector can extend lives of brain cancer patients

Specific commercial red algae could help combat food allergies

Some women with ovarian cancer do not receive beneficial surgical treatment, study finds

Large national effort shows promise in reducing both catheter use and UTI rates

Nivolumab and ipilimumab combination could lead to effective treatment options for SCLC patients

Severe obesity may contribute to infection risk after bypass surgery

PAN-EX supports neoadjuvant chemotherapy in high-risk rectal cancer

BRCA gene mutations raise risk of breast, ovarian and other cancers

Supportive leadership can help overcome language barriers to educate new parents about SBS/AHT

Scientists use optogenetics technique to increase memory in mice brain

New IRAP inhibitors may hold promise for improving cognitive functions in animal models

Deployed military soldiers three times more likely to suffer non-combat musculoskeletal injuries

Multiple cell and gene therapies can enhance cardiac function in mice modeled with MI

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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