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$CD34+ cell therapy improves angina frequency in no option patients with class III/IV angina refractory$

CD34+ cell therapy improves angina frequency in no option patients with class III/IV angina refractory

A two-year, multi-center clinical study with 167 patients with class III-IV refractory angina randomized to low and high dose CD34+ cells or placebo has revealed that patients who received either a high or low dose of CD34 -- a member of a family of proteins that have an impact on vascular-associated tissue -- cells had a significant reduction in angina frequency over patients who received placebo.

2 Jun 2016

Experts urge cancer researchers to use old, obese mice for preclinical immunotherapy studies

Researchers should include laboratory mice that are old and obese in their studies of immunotherapy treatments for cancer, according to a review article by Saint Louis University scientists.

2 Jun 2016

New osseointegrated press-fit implant reduces infection risk for above knee amputees

A new study in today's issue of the Journal of Bone and Joint Surgery found minimal risk for severe infection with osseointegrated implants--a newer prosthetic system, press-fitted directly into the femur bone--that enables bone growth over a metal, robotic prosthetic limb in patients with above knee amputations.

2 Jun 2016

Interventions for breast cancer patients show benefits based on women’s stress levels

Is a couples' support group or an enhanced couples' group therapy intervention with skill instruction more effective for helping women diagnosed with early stage breast cancer? According to research from an investigator at Rutgers Cancer Institute of New Jersey and colleagues from other facilities across the country, neither intervention is more dominant, but each has its own benefits depending on the stress level of the patient.

2 Jun 2016

Just one stroke risk factor signals anticoagulation need in AF

The risk of stroke or systemic embolism is significantly increased in atrial fibrillation patients with just one risk factor apart from gender, say researchers.

2 Jun 2016

Researchers call for more accurate renal assessment in stroke patients

Unrecognised renal insufficiency is common among patients with acute stroke and is associated with a significantly increased risk of in-hospital mortality or severe disability at discharge, say researchers.

2 Jun 2016

Children's Hospital of Pittsburgh of UPMC supports parents’ presence with children during resuscitation

Inviting parents to the bedside while their child receives CPR is supported by professional associations, joint position and policy statements, and clinical practice guidelines, but hospitals often find that putting those recommendations into practice requires more than a new policy.

1 Jun 2016

New research reveals functioning of brain's cleaning up mechanisms in neurodegenerative diseases

A piece of research led by the Achucarro Basque Center for Neuroscience, the University of the Basque Country, and the Ikerbasque Foundation has revealed how the brain's cleaning up mechanisms function in neurodegenerative diseases.

1 Jun 2016

Readmission rates after major cancer procedures depend on patient cohort, hospital characteristics

Readmission rates after complex cancer operations tend to be higher in hospitals that are considered to be vulnerable because they serve as safety nets in their communities or have a high number of Medicaid patients.

1 Jun 2016

Luteal phase of menstrual cycle may help thwart smoking behavior in women

Women who want to quit smoking may have better success by carefully timing their quit date with optimal days within their menstrual cycle, according to a new study from researchers at the Perelman School of Medicine at the University of Pennsylvania.

1 Jun 2016

Demand for Isansys’ Patient Status Engine wireless patient monitoring platform exceeds expectations

Demand for real-time continuous data, including personal health information, early warning scores, and alerting when a patient's condition is deteriorating, is driving the market for complete monitoring systems in hospital and home care settings globally.

From Isansys Lifecare Ltd. 1 Jun 2016

Study provides new insights into molecular basis of CaSR-related human diseases

A study led by researchers at Georgia State University provides new insights into the molecular basis of human diseases resulting from mutations in the calcium-sensing receptor (CaSR), a protein found in cell membranes.

1 Jun 2016

Researchers identify potential therapeutic target against oncogenic viral infection

A benign virus normally found in the skin can lead to a type of rare, lethal skin cancer. Specifically, infection by the Merkel cell polyomavirus can lead to Merkel cell carcinoma in immune-compromised individuals.

1 Jun 2016

Rome IV criteria helps diagnose, treat gastrointestinal conditions in children

A child feels nauseated all the time, but no medical test can find what is wrong. Or a child vomits regularly, but there's no illness or eating disorder to explain it. These, and other stomach and bowel-related problems with no obvious causes, are called functional gastrointestinal disorders.

1 Jun 2016

Altered circadian somatostatin expression linked to bipolar disorder

Results of the first study of its kind to link abnormalities in circadian rhythms to changes in specific neurotransmitters in people with bipolar disorder will be published this week in the journal Biological Psychiatry.

1 Jun 2016

New research refutes hypothesis that elite endurance training causes right ventricle damage

In 2012, Belgium scientists published a study that concluded that repeated bouts of intensive endurance exercise at the elite level may result in the pathological enlargement of the right ventricle, which, according to the article, is associated with potential health hazards including sudden cardia death.

1 Jun 2016

Betrixaban scores near miss for extended thromboprophylaxis

Extended thromboprophylaxis with the direct factor Xa inhibitor betrixaban just fails to show superiority to standard treatment with enoxaparin in acutely ill medical patients.

1 Jun 2016

Aquatic resistance training improves tibiofemoral cartilage quality in postmenopausal women with knee pain

Postmenopausal women with mild knee osteoarthritis, who may avoid strenuous exercise due to pain, can safely promote cartilage health and improve aerobic fitness with intensive aquatic resistance training.

31 May 2016

UN’s 90-90-90 program could be a cost-effective way to control global AIDS epidemic

A new study finds that implementing the United Nations targets for HIV testing and treatment would be an expensive but ultimately very cost-effective way to increase survival, reduce the number of children orphaned by HIV, and contain the global AIDS epidemic.

31 May 2016

Researchers identify new genetic drivers of adrenal cancer

Cancer researchers in Würzburg, in cooperation with the international Cancer Genome Atlas Research Network, have identified new genetic drivers of adrenal cancer. Würzburg was the center of coordination of the European scientists.

30 May 2016

Hospital News and Research

CD34+ cell therapy improves angina frequency in no option patients with class III/IV angina refractory

Experts urge cancer researchers to use old, obese mice for preclinical immunotherapy studies

New osseointegrated press-fit implant reduces infection risk for above knee amputees

Interventions for breast cancer patients show benefits based on women’s stress levels

Just one stroke risk factor signals anticoagulation need in AF

Researchers call for more accurate renal assessment in stroke patients

Children's Hospital of Pittsburgh of UPMC supports parents’ presence with children during resuscitation

New research reveals functioning of brain's cleaning up mechanisms in neurodegenerative diseases

Readmission rates after major cancer procedures depend on patient cohort, hospital characteristics

Luteal phase of menstrual cycle may help thwart smoking behavior in women

Demand for Isansys’ Patient Status Engine wireless patient monitoring platform exceeds expectations

Study provides new insights into molecular basis of CaSR-related human diseases

Researchers identify potential therapeutic target against oncogenic viral infection

Rome IV criteria helps diagnose, treat gastrointestinal conditions in children

Altered circadian somatostatin expression linked to bipolar disorder

New research refutes hypothesis that elite endurance training causes right ventricle damage

Betrixaban scores near miss for extended thromboprophylaxis

Aquatic resistance training improves tibiofemoral cartilage quality in postmenopausal women with knee pain

UN’s 90-90-90 program could be a cost-effective way to control global AIDS epidemic

Researchers identify new genetic drivers of adrenal cancer

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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