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CWRU School of Medicine receives grant to fund a Public Health Practice Based Research Network

Case Western Reserve University (CWRU) School of Medicine (SOM) has received a Robert Wood Johnson grant to fund a Public Health Practice Based Research Network called The Ohio Research Association for Public Health Improvement (RAPHI).

19 Nov 2009

Interim data from Geron's ongoing imetelstat trial presented at the AACR-NCI-EORTC conference

Geron Corporation today announced the presentation of interim data from its ongoing trial of imetelstat (GRN163L), a telomerase inhibitor drug, in patients with refractory, advanced solid cancers at the 2009 AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics in Boston.

19 Nov 2009

Early diagnosis and treatment is crucial for pulmonary hypertension, a rare but deadly disease

We often hear about the perils of high blood pressure, but many Canadians are unaware that high blood pressure in the lungs - known as pulmonary hypertension (PH) - can also have fatal consequences. This month, the Pulmonary Hypertension Association of Canada hopes to raise awareness about PH - a rare but serious disease that can strike at any time and has no regard for race, age or gender.

19 Nov 2009

Treatment of iron deficiency can improve symptoms and quality of life in CHF patients

Intravenous (I.V.) iron treatment with ferric carboxymaltose to reverse iron deficiency can significantly improve symptoms, exercise tolerance and quality of life for chronic heart failure (CHF) patients, researchers said in a late-breaking clinical trial presentation at the American Heart Association's Scientific Sessions 2009.

19 Nov 2009

Book on pediatric IBD launched

Chronic inflammatory bowel disease (IBD) encompasses Crohn's disease, ulcerative colitis and indeterminate colitis. The distinct phenotype in pediatric and adolescent patients and the difference from adult IBD make early-onset IBD a unique subgroup requiring specific therapeutic considerations. In this book, leading experts from the USA, Europe and Israel present new data on the genetics, epidemiology, pathology and pathogenesis of pediatric IBD. Imaging and endoscopy in the diagnosis of IBD are also discussed.

19 Nov 2009

Genetic identity of cellular receptor for the immune system's first-response antibody discovered

Researchers at the University of Alabama at Birmingham (UAB) have uncovered the genetic identity of a cellular receptor for the immune system's first-response antibody, a discovery that sheds new light on infection control and immune disorders. The discovery is such a crucial part of immunology that UAB researchers, in conjunction with Japanese researchers, are asking that the gene linked to this antibody receptor be renamed to better describe its role in early immune responses.

19 Nov 2009

eHealthInsurance releases six-point checklist to get the most out of Medicare coverage

eHealthInsurance, the leading online source of health insurance for individuals, families, and small businesses, that now offers a new online Medicare resource, www.eHealthMedicare.com, today released a six-point checklist to help Medicare recipients make informed decisions about their Medicare options.

19 Nov 2009

Toddlers and obese children suffer more than youth when exposed to secondhand smoke

Toddlers and obese children suffer more than other youth when exposed to secondhand smoke, according to research presented at the American Heart Association's Scientific Sessions 2009.

19 Nov 2009

instaCare reports third quarter 2009 financial results

instaCare Corp., (OTC Bulletin Board: ISCR), a leading distributor of life-saving prescription drugs and at-home testing diagnostics for the chronically ill, and a leading developer of patentable technologies for e-pharmacy, e-health and EMR applications, reported financial results for the third quarter period-ended September 30, 2009.

19 Nov 2009

Study: EP4 agonist may reduce gastric bleeding and inflammation

Over 300 million patients use non-steroidal anti-inflammatory drugs (NSAIDs) in the world to treat pain, arthritis, fever and other diseases. Nearly 30% of the users suffer from gastric lesions and bleeding.

19 Nov 2009

FDA issues complete response for Rituxan, a drug for treating chronic lymphocytic leukemia

Genentech, Inc., a wholly-owned member of the Roche Group (SIX: RO, ROG; OTCQX: RHHBY), and Biogen Idec announced today that the U.S. Food and Drug Administration (FDA) issued a complete response on the companies’ applications for Rituxan® (rituximab) plus fludarabine and cyclophosphamide (FC) for the treatment of people with previously untreated and previously treated chronic lymphocytic leukemia (CLL).

19 Nov 2009

Halifax researcher wins Prix Galien Research Award

Dr. Donald Weaver, a Halifax researcher with unmatched credentials, received the Prix Galien Research Award at a ceremony in Ottawa last night. Known as the Nobel Prize of pharmaceutical research, this award is the highest distinction worldwide for biopharmaceutical work, and the most prestigious in the field of Canadian pharmaceutical research and innovation.

19 Nov 2009

Opiate-based painkillers can increase tumor-cell proliferation, says new study

Although morphine has been the gold-standard treatment for postoperative and chronic cancer pain for two centuries, a growing body of evidence is showing that opiate-based painkillers can stimulate the growth and spread of cancer cells.

19 Nov 2009

Chronic hepatitis B seems to progress faster in men, report scientists

Scientists in China are reporting discovery of unusual liver proteins, found only in males, that may help explain the long-standing mystery of why the hepatitis B virus (HBV) sexually discriminates -- hitting men harder than women. Their study has been published online in ACS' Journal of Proteome Research, a monthly publication.

19 Nov 2009

Women with multiple sclerosis are less likely to have pregnancy complicaitons

There is good news for women with multiple sclerosis (MS) who are pregnant or thinking about becoming pregnant. A new study shows that pregnant women with multiple sclerosis are only slightly more likely to have cesarean deliveries and babies with a poor prenatal growth rate than women who do not have MS.

19 Nov 2009

Once-a-day dosing clinical study of udenafil for erectile dysfunction completed

Dong-A Pharmaceutical Co., Ltd. and Dong-A PharmTech, Co. Ltd. announced today that it has completed a 240 patient once-a-day dosing clinical study of udenafil, its new long acting phosphodiesterase type 5 (PDE-5) inhibitor for erectile dysfunction (ED).

19 Nov 2009

Patients with recent-onset schizophrenia have raised levels of inflammatory substances

Researchers at the Swedish medical university Karolinska Institutet have discovered that patients with recent-onset schizophrenia have higher levels of inflammatory substances in their brains. Their findings offer hope of being able to treat schizophrenia with drugs that affect the immune system.

18 Nov 2009

St. Jude Medical announces implantation of the first patient in China with its Eon rechargeable neurostimulator

St. Jude Medical, Inc. announced today that a 62-year-old man from Shenzhen, Guangdong province has become the first patient in China to be implanted with the Eon™ neurostimulator, a rechargeable device used to help manage chronic pain. Despite prior back surgeries, the patient suffered from chronic back pain for more than a decade.

18 Nov 2009

Data on Synta Pharmaceuticals' STA-9090 synthetic inhibitor of Hsp90 presented

Synta Pharmaceuticals Corp., a biopharmaceutical company focused on discovering, developing, and commercializing small molecule drugs to treat severe medical conditions, today announced that preclinical data presented at the AACR-NCI-EORTC Conference on Molecular Targets and Cancer Therapeutics shows that STA-9090, a novel, synthetic inhibitor of heat shock protein 90 (Hsp90), demonstrated strong activity in multiple tumor models.

18 Nov 2009

Gene-diet interaction influencing BMI and obesity replicated in three independent studies

Tufts University researchers have identified a gene-diet interaction that appears to influence body weight and have replicated their findings in three independent studies. Men and women carrying the CC genotype demonstrated higher body mass index (BMI) scores and a higher incidence of obesity, but only if they consumed a diet high in saturated fat. These associations were seen in the apolipoprotein A-II gene (APOA2) promoter.

18 Nov 2009

Chronic News and Research

CWRU School of Medicine receives grant to fund a Public Health Practice Based Research Network

Interim data from Geron's ongoing imetelstat trial presented at the AACR-NCI-EORTC conference

Early diagnosis and treatment is crucial for pulmonary hypertension, a rare but deadly disease

Treatment of iron deficiency can improve symptoms and quality of life in CHF patients

Book on pediatric IBD launched

Genetic identity of cellular receptor for the immune system's first-response antibody discovered

eHealthInsurance releases six-point checklist to get the most out of Medicare coverage

Toddlers and obese children suffer more than youth when exposed to secondhand smoke

instaCare reports third quarter 2009 financial results

Study: EP4 agonist may reduce gastric bleeding and inflammation

FDA issues complete response for Rituxan, a drug for treating chronic lymphocytic leukemia

Halifax researcher wins Prix Galien Research Award

Opiate-based painkillers can increase tumor-cell proliferation, says new study

Chronic hepatitis B seems to progress faster in men, report scientists

Women with multiple sclerosis are less likely to have pregnancy complicaitons

Once-a-day dosing clinical study of udenafil for erectile dysfunction completed

Patients with recent-onset schizophrenia have raised levels of inflammatory substances

St. Jude Medical announces implantation of the first patient in China with its Eon rechargeable neurostimulator

Data on Synta Pharmaceuticals' STA-9090 synthetic inhibitor of Hsp90 presented

Gene-diet interaction influencing BMI and obesity replicated in three independent studies

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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