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Researchers develop new quantitative assessment of motor control in kids with cerebral palsy

Children with cerebral palsy frequently undergo invasive surgeries -- lengthening tendons, rotating bones, transferring muscles to new locations -- in hopes of improving their physical ability to walk or move.

28 Apr 2016

HBcrAg may predict HCC development

Research suggests a role for hepatitis B core-related antigen in the prediction of hepatocellular carcinoma development in nucleos(t)ide analogue treatment-naïve patients with chronic hepatitis B virus infection.

27 Apr 2016

Bonn researchers identify new technique to measure activity of brown fat cells

Brown fat cells can burn fat to generate heat. University of Bonn researchers have discovered a new method to measure the activity of brown fat cells in humans and mice. The researchers showed that microRNA-92a can be used as an indirect measure for the activity of energy consuming brown fat cells. They showed that a small blood sample was sufficient. Results were published in "Nature Communications," a well-known scientific journal.

27 Apr 2016

Clinical study to evaluate safety of investigational cell therapy to treat chronic motor deficits after stroke

University Hospitals Case Medical Center is the first surgical site for a Phase 2b clinical trial study to further evaluate the safety and efficacy of an investigational cell therapy for the treatment of chronic motor deficit following an ischemic stroke.

27 Apr 2016

New study on retroviral DNA could help improve treatments for HIV infection

When retroviruses such as HIV infect a cell, they first make a copy of their RNA genome in the form of DNA. The relatively short viral DNA strand then moves to the cell nucleus, where it inserts itself into the host cell's DNA.

27 Apr 2016

Acid suppression drugs frequently prescribed for high-risk newborns, study shows

Since 2006, several published studies have associated the use of some acid suppression medications in hospitalized high-risk babies with infections, necrotizing enterocolitis and increased risk of death. Those medications - histamine-2 receptor antagonists, such as ranitidine (Zantac and others), and proton pump inhibitors, such as esomeprazole (Nexium and others) - were originally approved by the U.S. Food and Drug Administration for use in adults and older children.

27 Apr 2016

New research suggests fasting not required before cholesterol, triglyceride measurement

New research from Denmark, Canada and the US involving more than 300,000 individuals suggests that patients do not need to check their cholesterol levels on an empty stomach. So far fasting has been required before cholesterol and triglyceride measurement in all countries except Denmark, where non-fasting blood sampling has been used since 2009.

27 Apr 2016

Two London students make innovative medical devices to improve lives of people with Parkinson’s disease

Two London students, who have invented separate pieces of medical technology that could help revolutionise the lives of people with Parkinson’s disease, could soon see their innovative devices available to millions of sufferers after they were shortlisted for a prestigious award.

27 Apr 2016

Regular aspirin use may help reduce risk of bile duct cancer

Regular use of aspirin was linked with a significantly reduced risk of developing bile duct cancer, also called cholangiocarcinoma, in a recent study. The findings, which are published in the journal Hepatology, indicate that additional research on the potential of aspirin for preventing bile duct cancer is warranted.

27 Apr 2016

New fruit fly model study reveals metabolic pathway that can be targeted to treat FXS patients

Fragile X syndrome (FXS) is the most common genetically inherited cause of intellectual disability in humans. New research shows how the hormone insulin -- usually associated with diabetes -- is involved in the daily activity patterns and cognitive deficits in the fruitfly model of FXS, according to a new study from the Perelman School of Medicine at the University of Pennsylvania published online this month in Molecular Psychiatry in advance of the print issue.

27 Apr 2016

Derivatives of female sex hormones can influence natural melanin production, study suggests

When skin cells responsible for pigmentation are exposed to estrogen or progesterone, the cells respond by adjusting their melanin production, resulting in either skin darkening or lightening. Although pregnant women often experience alterations in skin pigmentation, the reason for the changes has long puzzled physicians.

27 Apr 2016

Researchers test potential positive effects of micro-injury in mice modeled with AD

Researchers testing the potential positive effects of "micro-injury" by brief insertion of a small needle into the hippocampal region of mice modeled with Alzheimer's disease (AD) have found that the procedure not only stimulated the hippocampus into regenerative activity, but also reduced β-amyloid plaques, a hallmark of AD.

27 Apr 2016

OSMR gene plays key role in driving growth of glioblastoma tumors

Glioblastoma is the most aggressive type of brain tumor in adults. Unfortunately, there are no effective treatments for the disease. On average, patients succumb just 16 months after diagnosis.

27 Apr 2016

Series of routine tests may not be beneficial to patients with age-related disorder

A series of tests physicians routinely order to help diagnose and follow their patients with an elevated antibody level that is a marker for cancer risk, often do not benefit the patient but do increase health care costs, pathologists report.

27 Apr 2016

Understanding need for supplemental cancer screening for women with dense breasts

In a study appearing in the April 26 issue of JAMA, Elizabeth A. Rafferty, M.D., formerly of Massachusetts General Hospital, Boston, and colleagues evaluated the screening performance of digital mammography combined with tomosynthesis (a type of imaging) compared with digital mammography alone for women with varying levels of breast density.

27 Apr 2016

New national database could help identify major influences on miscarriage

A new national database could help relieve the misery of miscarriage for thousands of women.

26 Apr 2016

Acute liver failure after massive hepatectomy improves with liver cell transplantation

Liver failure often occurs after an extensive hepatectomy, which is the surgical resection of the liver. While liver cell transplantation is a useful therapy for acute liver failure after massive hepatectomy, when cells are transplanted through liver portal veins raises the risk of embolization, such as the formation and movement of a blood clot, often with fatal consequences.

26 Apr 2016

Study identifies risk factors for asparaginase-induced pancreatitis in ALL patients

Researchers have identified a rare genetic variation associated with a dramatically increased risk of severe acute pancreatitis in acute lymphoblastic leukemia (ALL) patients treated with the chemotherapy agent asparaginase. St. Jude Children's Research Hospital led the study, which appears today in the Journal of Clinical Oncology.

26 Apr 2016

High doses of commonly-used chemotherapy drug may increase survival rate of ALL patients

With a cure rate approaching 90 percent, acute lymphoblastic leukemia (ALL) - the most common type of childhood cancer - is often hailed as one of the "success stories" of modern cancer treatment. But up to 20 percent of patients with a high risk of relapse are not cured. That could change with the results from a clinical trial co-led by investigators from NYU Langone Medical Center, which shows giving high doses of a commonly-used chemotherapy drug increases the survival rate for these patients.

26 Apr 2016

Early maternal support boosts robust brain growth in kids

Children whose mothers were nurturing during the preschool years, as opposed to later in childhood, have more robust growth in brain structures associated with learning, memory and stress response than children with less supportive moms, according to research at Washington University School of Medicine in St. Louis.

26 Apr 2016

Hospital News and Research

Researchers develop new quantitative assessment of motor control in kids with cerebral palsy

HBcrAg may predict HCC development

Bonn researchers identify new technique to measure activity of brown fat cells

Clinical study to evaluate safety of investigational cell therapy to treat chronic motor deficits after stroke

New study on retroviral DNA could help improve treatments for HIV infection

Acid suppression drugs frequently prescribed for high-risk newborns, study shows

New research suggests fasting not required before cholesterol, triglyceride measurement

Two London students make innovative medical devices to improve lives of people with Parkinson’s disease

Regular aspirin use may help reduce risk of bile duct cancer

New fruit fly model study reveals metabolic pathway that can be targeted to treat FXS patients

Derivatives of female sex hormones can influence natural melanin production, study suggests

Researchers test potential positive effects of micro-injury in mice modeled with AD

OSMR gene plays key role in driving growth of glioblastoma tumors

Series of routine tests may not be beneficial to patients with age-related disorder

Understanding need for supplemental cancer screening for women with dense breasts

New national database could help identify major influences on miscarriage

Acute liver failure after massive hepatectomy improves with liver cell transplantation

Study identifies risk factors for asparaginase-induced pancreatitis in ALL patients

High doses of commonly-used chemotherapy drug may increase survival rate of ALL patients

Early maternal support boosts robust brain growth in kids

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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