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Psilocybin administration reduces reaction to social rejection in associated brain areas

Social ties are vital for mental and physical health. However, psychiatric patients in particular frequently encounter social exclusion and rejection. Furthermore, psychiatric patients often react more strongly to social rejection than healthy persons and this can have negative consequences for the development and treatment of psychiatric disorders.

19 Apr 2016

Experts discuss recent controversies related to breast cancer screening recommendations

In 2015, American Cancer Society caused a stir in the oncology community—and among women in general—with the updated recommendation that women of average risk for breast cancer should commence annual mammography at age 45.

19 Apr 2016

New drug combination before surgery may improve outcomes in breast cancer patients

Results from the I-SPY 2 trial show that giving patients with HER2-positive invasive breast cancer a combination of the drugs trastuzumab emtansine (T-DM1) and pertuzumab before surgery was more beneficial than the combination of paclitaxel plus trastuzumab.

19 Apr 2016

Newly launched TB-PACTS could be a valuable tool to combat world's leading infectious killer

The Critical Path Institute, the Special Programme for Research and Training in Tropical Diseases, TB Alliance, and St. George's, University of London, are pleased to announce the launch of the TB-Platform for Aggregation of Clinical TB Studies.

19 Apr 2016

Researchers find mechanism behind pancreatic cancer cells' resistance to certain drugs

Pancreatic cancer is on track to become the second leading cause of cancer-related deaths by 2020. These statistics are due, in part, to pancreatic cancer's resistance to most targeted cancer therapies. Working with pancreatic cancer cells, researchers have now found a mechanism that could be responsible for the cancer's resistance to at least one targeted approach.

19 Apr 2016

OASIS study to investigate link between SIDS and alteration on newborn hearing screen test

Seattle Children's is partnering on the launch of a study called the 'Oto-Acoustic Signals in SIDS'study that will investigate a possible association between Sudden Infant Death Syndrome (SIDS) and hearing alteration on the newborn hearing screen test.

19 Apr 2016

Delay in radiation therapy increases chances of DCIS recurrence in women

Delaying radiation therapy too long after surgery significantly increases the risk of recurrent tumors in women treated for very early, or what is referred to as "stage 0," breast cancer, according to new research at Washington University School of Medicine in St. Louis.

19 Apr 2016

New therapy strategy for liver disease shows initial measureable success with norUrso

The new therapy strategy for primary sclerosing cholangitis, a liver disease that at present still cannot be cured with medication, shows initial measureable success with the nor-ursodeoxycholic acid (norUrso).

19 Apr 2016

Researchers identify biological pathway that explains why current asthma therapies fail in many cases

Asthma is an enormous public health problem that continues to grow larger, in part because scientists don't fully understand how it is caused. Existing therapies don't cure the disease and often don't even significantly alleviate the symptoms. Now, scientists from the Perelman School of Medicine at the University of Pennsylvania and Rutgers University have identified a biological pathway that potentially explains why current asthma therapies don't work well in many cases—and might be targeted to help those patients.

19 Apr 2016

Study shows women may face decreased kidney damage from ischemia reperfusion injury

After a kidney transplant, women may experience decreased kidney damage from ischemia reperfusion injury compared to men due to the impact of gender-specific hormones, suggests a new preclinical study and an analysis of patient data published online in the Journal of Clinical Investigation from researchers at the Perelman School of Medicine at the University of Pennsylvania.

19 Apr 2016

Penn researchers report results of CAR therapy trial in brain cancer patients

Immune cells engineered to seek out and attack a type of deadly brain cancer known as glioblastoma (GBM) were found to have an acceptable safety profile and successfully migrate to and infiltrate tumors, researchers from Penn Medicine and Harvard University reported at the AACR Annual Meeting 2016.

19 Apr 2016

Researchers find way to attack a process that tumor cells use to escape effects of cancer drugs

Cancer cells often devise ways to survive even in the presence of toxic chemotherapy. Now, a research team led by investigators at Beth Israel Deaconess Medical Center has found a way to attack a process that tumor cells use to escape the effects of standard cancer drugs. The discovery is published online today in the journal Nature Cell Biology.

19 Apr 2016

Transplanted human islets prevent hypoglycemic events in Type 1 diabetes patients

Northwestern Medicine researchers are co-investigators in a breakthrough clinical trial that found transplanted human islets prevent hypoglycemic events and provide excellent glycemic control for patients with Type 1 diabetes with severe hypoglycemia.

19 Apr 2016

New computer algorithm can better characterize functional context of genomic variations in cancer

Cancer is rarely the result of a single mutation in a single gene. Rather, tumors arise from the complex interplay between any number of mutually exclusive abnormal changes in the genome, the combinations of which can be unique to each individual patient.

19 Apr 2016

Inhibiting adrenaline receptors reduces breast cancer brain metastases

While we look to invent new medicines to treat cancer, a parallel approach to repurpose existing medicines may be highly effective. Stress, mediated by adrenaline, has been suspected to promote cancer growth and this research study shows that by blocking adrenaline receptors in breast cancers, they are less successful in spreading to and growing in the brain.

19 Apr 2016

Radiotherapy needs likely to increase in all European countries by 2025

The demand for radiotherapy across all European countries will increase by an average of 16% between 2012 and 2025, with the highest expected increase being for prostate cancer cases (24%), according to a new study published in Radiotherapy and Oncology.

19 Apr 2016

Researchers devise method to stably internalize chemotherapy loaded microparticles into prostate cells

A collaborative Brigham and Women's Hospital and Johns Hopkins University co-led team has found proof-of-concept evidence for a potential cancer treatment that leverages microparticles and mesenchymal stem cells.

19 Apr 2016

Study: British adults agree to donate heart, kidney and lungs, but not eyes for transplant

Despite a shortage of corneas for transplant purposes, new research reveals that eyes are the one body part we are least likely to donate.

19 Apr 2016

Royal Society of Medicine, ITN Productions jointly launch new initiative ‘Doctors of the Future’

In a unique communications partnership, the Royal Society of Medicine and ITN Productions have launched a news and current affairs-style programme.

19 Apr 2016

Reducing hair loss during chemotherapy: an interview with Richard Paxman

The basic principle of chemotherapy is to damage the mitotic and metabolic processes in the cancer cells. The chemotherapy doesn't just target the cancer cells, it also targets the healthy cells, specifically ones that are rapidly dividing - our hair follicles are also rapidly dividing. We see damage to those hair cells, which then causes the hair to fall out.

From Paxman 19 Apr 2016

Hospital News and Research

Psilocybin administration reduces reaction to social rejection in associated brain areas

Experts discuss recent controversies related to breast cancer screening recommendations

New drug combination before surgery may improve outcomes in breast cancer patients

Newly launched TB-PACTS could be a valuable tool to combat world's leading infectious killer

Researchers find mechanism behind pancreatic cancer cells' resistance to certain drugs

OASIS study to investigate link between SIDS and alteration on newborn hearing screen test

Delay in radiation therapy increases chances of DCIS recurrence in women

New therapy strategy for liver disease shows initial measureable success with norUrso

Researchers identify biological pathway that explains why current asthma therapies fail in many cases

Study shows women may face decreased kidney damage from ischemia reperfusion injury

Penn researchers report results of CAR therapy trial in brain cancer patients

Researchers find way to attack a process that tumor cells use to escape effects of cancer drugs

Transplanted human islets prevent hypoglycemic events in Type 1 diabetes patients

New computer algorithm can better characterize functional context of genomic variations in cancer

Inhibiting adrenaline receptors reduces breast cancer brain metastases

Radiotherapy needs likely to increase in all European countries by 2025

Researchers devise method to stably internalize chemotherapy loaded microparticles into prostate cells

Study: British adults agree to donate heart, kidney and lungs, but not eyes for transplant

Royal Society of Medicine, ITN Productions jointly launch new initiative ‘Doctors of the Future’

Reducing hair loss during chemotherapy: an interview with Richard Paxman

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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