Syndrome News and Research

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25% of COVID-19 patients have lasting reduction in lung function

In a recent study posted to the Preprints with The Lancet SSRN* server, researchers evaluated the impairment of pulmonary function in individuals suffering from post-acute sequelae of coronavirus disease 2019 (COVID-19) (PASC) or long coronavirus disease (long COVID) symptoms after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections.

28 Feb 2023

Mass spectrometry-based identification of COVID-19 biomarkers

In a recent study published in the journal Metabolites, researchers reported that mass spectrometry (MS)-based metabolomic approaches have a high potential for biomarker discovery.

28 Feb 2023

Brain over-activation could be causing seizures and social deficits in genetic subtype of autism

Northwestern Medicine scientists have identified the cause of a genetic subtype of autism and schizophrenia that results in social deficits and seizures in mice and humans.

28 Feb 2023

Mutation in a single non-coding gene found to be the source of multisystemic smooth muscle dysfunction syndrome

A team of investigators from Massachusetts General Hospital, a founding member of Mass General Brigham and Mass General for Children has identified - for the first time - the mutation in a single non-coding gene of a young patient responsible for the extremely rare disease known as multisystemic smooth muscle dysfunction syndrome, which causes profound cerebrovascular, gastrointestinal and urologic impairment.

28 Feb 2023

Study finds unique epigenetic biosignature in individuals with post-COVID syndrome

A reprogramming of which genes are active, and which are not, is visible in post-COVID sufferers. This is shown in a study from Linköping University, Sweden, on a small group of individuals.

28 Feb 2023

The effects of Omicron emergence on seroprevalence and hybrid immunity in the Finnish adult population

Researchers evaluated SARS-CoV-2 seroprevalence and population-level humoral immunity among Finnish individuals between April 2020 and December 2022.

28 Feb 2023

COVID-19 does not increase the risk of Streptococcus pneumoniae infection

SARS-CoV-2 infection does not appear to influence pneumococcal colonization in the upper respiratory tract.

28 Feb 2023

Critical COVID-19 infection characterized by a shift from naïve T cell phenotypes to an expansion of cytotoxic CD4+ T lymphocyte subsets

Researchers immunophenotyped T lymphocyte responses among unvaccinated individuals, representative of the entire spectrum of the clinical presentation of COVID-19.

28 Feb 2023

COVID-19 increases risk of developing chronic diseases

Researchers determine the correlation between severity of SARS-CoV-2 infection, age, and new onset of chronic or worsening of pre-existing conditions.

28 Feb 2023

A review of respiratory viruses monitored in wastewater samples

Researchers review previous studies discussing the content or respiratory viruses in wastewater samples.

28 Feb 2023

The evolution of transmissible variants harboring mutations consistent with immune escape in mild community COVID-19 cases

Researchers investigate whether transmissible SARS-CoV-2 variants developed during infection by culturing and sequencing strains obtained from serial oral and nasal samples of community-residing COVID-19 patients.

28 Feb 2023

Rare Diseases Action Plan for England focuses on providing better care and reducing health inequalities

A new Rare Diseases Action Plan for England will be published today (Tuesday 28 February) that will ensure those living with these conditions receive better care and treatment, fairer access to testing and have continued support.

28 Feb 2023

Popular artificial sweetener associated with elevated risk of heart attack and stroke, study shows

New Cleveland Clinic research showed that erythritol, a popular artificial sweetener, is associated with an increased risk of heart attack and stroke.

27 Feb 2023

Latest treatments for cardiac emergencies to be revealed at ESC Acute CardioVascular Care 2023

The latest evidence on the treatment of urgent heart problems will be revealed at ESC Acute CardioVascular Care 2023, a scientific congress of the European Society of Cardiology.

27 Feb 2023

Can the gut microbiota and metabolome explain variation in anti-SARS-CoV-2 vaccination responses in immunosuppressed IBD patients?

Researchers explored the connection between the metabolic function of the gut microbiota, its composition, and immune response to SARS-CoV-2 vaccination in IBD patients.

27 Feb 2023

Does a negative COVID-19 test before air travel reduce the spread of COVID-19 transmission during and after travel?

Researchers assessed the impact of pre-departure testing on SARS-CoV-2-positivity rates post-arrival among international travelers.

27 Feb 2023

High-dose ivermectin does not reduce COVID-19 symptom duration among mild-to-moderate outpatients

Researchers evaluate the efficacy of ivermectin in a maximum dosage of 600 μg/kg/day over six days in treating early mild-to-moderate COVID-19.

27 Feb 2023

Study shows COVID-19 rates were likely forty-times higher than CDC estimates during BA.4/BA.5 dominant period in the U.S.

Researchers evaluate the prevalence of SARS-CoV-2 infections and the incidence of long COVID during BA.4/BA.5 dominant period.

27 Feb 2023

Rebounding of COVID-19 symptoms and viral load are common among untreated COVID-19 patients

Researchers characterize COVID-19 symptom and viral load rebounds among untreated individuals with mild-to-moderate SARS-CoV-2 infection.

27 Feb 2023

Cedars-Sinai addresses life-threatening aorta condition

Her husband and their five children call Rosa Wernher "the Energizer bunny" because she is always on the go. For decades, not even her genetically inherited Marfan syndrome could keep her off her feet to prevent her from oil painting or from gliding down a ski slope--until it did.

25 Feb 2023

Syndrome News and Research

25% of COVID-19 patients have lasting reduction in lung function

Mass spectrometry-based identification of COVID-19 biomarkers

Brain over-activation could be causing seizures and social deficits in genetic subtype of autism

Mutation in a single non-coding gene found to be the source of multisystemic smooth muscle dysfunction syndrome

Study finds unique epigenetic biosignature in individuals with post-COVID syndrome

The effects of Omicron emergence on seroprevalence and hybrid immunity in the Finnish adult population

COVID-19 does not increase the risk of Streptococcus pneumoniae infection

Critical COVID-19 infection characterized by a shift from naïve T cell phenotypes to an expansion of cytotoxic CD4+ T lymphocyte subsets

COVID-19 increases risk of developing chronic diseases

A review of respiratory viruses monitored in wastewater samples

The evolution of transmissible variants harboring mutations consistent with immune escape in mild community COVID-19 cases

Rare Diseases Action Plan for England focuses on providing better care and reducing health inequalities

Popular artificial sweetener associated with elevated risk of heart attack and stroke, study shows

Latest treatments for cardiac emergencies to be revealed at ESC Acute CardioVascular Care 2023

Can the gut microbiota and metabolome explain variation in anti-SARS-CoV-2 vaccination responses in immunosuppressed IBD patients?

Does a negative COVID-19 test before air travel reduce the spread of COVID-19 transmission during and after travel?

High-dose ivermectin does not reduce COVID-19 symptom duration among mild-to-moderate outpatients

Study shows COVID-19 rates were likely forty-times higher than CDC estimates during BA.4/BA.5 dominant period in the U.S.

Rebounding of COVID-19 symptoms and viral load are common among untreated COVID-19 patients

Cedars-Sinai addresses life-threatening aorta condition

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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