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Dapagliflozin trial results indicate improvement in key glycemic measures in treatment-naive type 2 diabetes

Findings published in Diabetes Care from a 12-week, Phase IIb dose-ranging study showed that dapagliflozin, a novel, selective, sodium glucose co-transporter2 (SGLT2) inhibitor, produced clinically meaningful reductions across all key glycemic measures studied [glycosylated hemoglobin level (HbA1c), fasting plasma glucose (FPG), and postprandial plasma glucose (PPG)] in treatment-naive type 2 diabetes patients, compared to placebo.

29 Mar 2009

Takeda expands into Canada

Takeda Pharmaceutical Company Limited and its wholly-owned subsidiary, Takeda Pharmaceuticals North America, Inc. today announced the establishment of Takeda Canada Inc., expanding the company's North American presence into the world's eighth largest pharmaceutical market.

29 Mar 2009

Protein from tick saliva shows potential for myasthenia gravis treatment

Looking for a better treatment for the autoimmune disease myasthenia gravis, researchers have found that a protein in tick saliva shows promise in limiting the severity of the disease in an animal model in a study published in the Annals of Neurology.

29 Mar 2009

Positive phase 3 uveitis trial results for voclosporin

Isotechnika Inc. has announced that their partner, Lux Biosciences, Inc., reported the results from the three Phase 3 LUMINATE trials investigating voclosporin oral capsule (LUVENIQ or LX211) for the treatment of uveitis.

29 Mar 2009

Data suggesting that omacetaxine can eradicate leukemic stem cells may offer a breakthrough for CML

Data showing the ability of omacetaxine to kill leukemic stem cells in mouse models with drug-resistant chronic myelogenous leukemia (CML) are the subject of an advance online publication in the journal Leukemia, ChemGenex Pharmaceuticals Limited (ASX:CXS and NASDAQ:CXSP) announced today.

29 Mar 2009

Chronic obstructive pulmonary disease-related problems hard to swallow

Patients with moderate to severe chronic obstructive pulmonary disease (COPD) exhibit a disordered breathing-swallowing pattern that may account for their higher risk of aspiration pneumonia, according to new research from the University of Pittsburgh.

29 Mar 2009

Mutations in a gene may stunt lung development in children

Mutations in a gene may cause poor lung development in children, making them more vulnerable to diseases such as chronic obstructive pulmonary disease (COPD) later in life, say researchers at the University of Pittsburgh Graduate School of Public Health and the German Research Center for Environmental Health.

29 Mar 2009

AHIP, BCBS say insurers willing to stop basing premiums on members' health status if all U.S. residents are required to obtain coverage

In a letter to leaders of the Senate Finance Committee and the Senate Health, Education, Labor and Pensions Committees on Tuesday, America's Health Insurance Plans and the BlueCross BlueShield Association said that their memberships would be willing to end the practice of charging different premiums based on individuals' health status if all U.S. residents were required to obtain coverage, CongressDaily reports (Edney, CongressDaily, 3/25).

25 Mar 2009

Rockefeller neuroscientist applies basic science to health care reform

A self-described "molecular sociologist" is extending his basic research to the national policy debate on health care reform. Bruce McEwen, head of the Laboratory of Neuroendocrinology, led a panel of scientific experts last month at the Institute of Medicine's Summit on Integrative Medicine and the Health of the Public. The Institute is the most prominent independent medical advisory board in the country and will release a report from the conference in November, as Congress is likely to be considering major health care legislation.

25 Mar 2009

Discovery of a protein link to wound healing

Diabetes and eczema may appear to be two completely unrelated diseases.

24 Mar 2009

Collaborative care intervention helps improve management of chronic pain

Patients with chronic pain who took part in a collaborative care intervention that included patient and clinician education and symptom monitoring and feedback to the primary care physician had improvements in pain-related disability and intensity, compared to usual care, according to a study in the March 25 issue of JAMA, the Journal of the American Medical Association.

24 Mar 2009

Fit women much less likely to die from breast cancer

Physically fit women are less likely to die from breast cancer, according to a study by researchers at the University of South Carolina Arnold School of Public Health.

24 Mar 2009

Orexo reports on efficacy study in allergic rhinitis with OX914

Orexo has reported clinical results from an experimental phase IIa safety and efficacy study in allergic rhinitis with OX914, the first compound in its Phosphodiesterase 4 (PDE4) inhibitor program.

24 Mar 2009

How to predict post-operative enteral nutrition problems

Percutaneous endoscopic gastrostomy (PEG) has become one of the most useful and established enteral nutrition techniques.

24 Mar 2009

Speakers at White House-sponsored forum discuss possibility of public health coverage option, preventive care

Congressional Democrats intend to pass health care reform legislation by "August or September" that could include an option allowing uninsured U.S. residents to buy into a government-run health care plan, Senate Appropriations Labor, Health and Human Services, Education, and Related Agencies Subcommittee Chair Tom Harkin (D-Iowa) said on Monday, Kansas Health Institute News reports.

24 Mar 2009

Super-microsurgical technique brings hope to breast cancer patients with lymphedema

Breast cancer patients with lymphedema in their upper arm experienced reduced fluid in the swollen arm by up to 39 percent after undergoing a super-microsurgical technique known as lymphaticovenular bypass, report researchers at The University of Texas M. D. Anderson Cancer Center.

23 Mar 2009

Smoking linked to greater risk for pancreatitis

Smoking appears to be associated with an increased risk of acute and chronic pancreatitis, according to a report in the March 23 issue of Archives of Internal Medicine.

23 Mar 2009

Physical abuse raises women's health costs by 42 percent

Women experiencing physical abuse from intimate partners spent 42 percent more on health care per year than non-abused women, according to a long-term study of more than 3,000 women.

23 Mar 2009

More cancer patients cured according to new data on cancer survival in Europe

New data and analyses from a long-running study of cancer survival in Europe have shown that the number of people actually cured of cancer - rather than just surviving for at least five years after diagnosis - is rising steadily.

23 Mar 2009

Red and processed meat linked to greater risk of death from all causes

Individuals who eat more red meat and processed meat appear to have a modestly increased risk of death from all causes and also from cancer or heart disease over a 10-year period, according to a report in the March 23 issue of Archives of Internal Medicine.

23 Mar 2009