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No benefit from nifedipine widely used to prevent premature births

A trial where a popular drug was compared with a placebo found it worked no better at maintaining pregnancy after the initial bout of preterm labour is halted.

26 Nov 2008

Peregrine Pharmaceuticals awarded U.S. patent for anti-viral applications of phospholipid-targeting antibodies

Peregrine Pharmaceuticals, Inc. has announced that the U.S. Patent and Trademark Office has issued U.S. Patent Number No. 7,455,833, which includes broad claims covering anti-viral applications of antibodies that directly bind to aminophospholipids.

25 Nov 2008

Discovery may lead to new therapeutic approaches for pain reduction

By manipulating the appearance of a chronically achy hand, researchers have found they could increase or decrease the pain and swelling in patients moving their symptomatic limbs.

25 Nov 2008

Call for greater caution in prescribing inhaled corticosteroids to COPD sufferers

Lung disease experts at Johns Hopkins are calling for physicians to show much greater caution in prescribing inhaled corticosteroid drugs for people with chronic obstructive pulmonary disease after finding evidence that the widely used anti-inflammatory medications increase the risk of pneumonia by a full third.

25 Nov 2008

New advance in the treatment of sickle cell anaemia

Sickle cell anaemia is a genetic disease characterised by the sickling of red blood cells in patients suffering from hypoxia (around 100,000 cases in Europe and North America).

25 Nov 2008

CardioVascular BioTherapeutics doses first patient in trial for severe coronary heart disease

CardioVascular BioTherapeutics, Inc. , announced today that it has dosed the first patient in North America (NA) as part of its ACORD Phase II clinical trial to treat patients with severe coronary heart disease.

25 Nov 2008

Febuxostat recommended by panel for treatment of hyperuricemia in patients with gout

Takeda Pharmaceutical Company Limited and its wholly-owned subsidiary, Takeda Global Research & Development Center, Inc., U.S., announced that the Arthritis Advisory Committee of the U.S. Food and Drug Administration (FDA) recommended that the FDA approve febuxostat for the treatment of hyperuricemia in patients with gout.

25 Nov 2008

Patients with severe traumatic brain injuries can relearn social communication skills

According to new research from Australia patients who have suffered traumatic brain injuries can benefit from being re-educated in important social communication skills.

25 Nov 2008

MorphoSys granted U.S. patent on antibodies against GM-CSF to treat inflammatory disorders

MorphoSys AG and the University of Melbourne announced today that the U.S. Patent & Trademark Office (USPTO) has confirmed that it will issue U.S. Patent No. 7,455,836, covering key uses of antibodies against GM-CSF.

25 Nov 2008

FDA approves lung analysis software from VIDA Diagnostics

VIDA Diagnostics Inc., a University of Iowa Research Foundation licensee and UI Technology Innovation Center business incubator tenant, announced today that its primary product, Pulmonary Workstation 2.0 (PW2) has obtained FDA 510(k) clearance for sale.

24 Nov 2008

Telephone counseling may be as effective as face-to-face counseling in weight loss maintenance

Face-to-face and telephone follow-up sessions appear to be more effective in the maintenance of weight loss for women from rural communities compared with weight loss education alone, according to a report in the November 24 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

24 Nov 2008

Double-balloon enteroscopy offers cost-effective approach for obscure GI bleeding

A cost-effectiveness analysis conducted by researchers at Stanford University Hospital in Calif., shows that an initial double-balloon enteroscopy (DBE) is a cost-effective approach for patients with obscure gastrointestinal (GI) bleeding.

24 Nov 2008

Discovery of novel drug target for chronic lymphocytic leukemia

Researchers at the University of California, San Diego (UCSD) and the Moores UCSD Cancer Center have discovered what could be a novel drug target for an often difficult-to-treat form of leukemia.

24 Nov 2008

Ustekinumab receives positive opinion in Europe for treatment of plaque psoriasis

Janssen-Cilag announced today that ustekinumab, the first in a new class of biologics, has received a positive opinion for the treatment of moderate to severe plaque psoriasis from the European Committee for Medical Products for Human Use (CHMP).

24 Nov 2008

Medarex starts phase 1b clinical trial with MDX-1106 for the treatment of cancer

Medarex, Inc. has announced it has initiated a Phase 1b clinical trial for MDX-1106 (ONO-4538: development code of Ono Pharmaceutical Co., Ltd.), a fully human anti-PD-1 antibody for the treatment of cancer.

24 Nov 2008

King Pharmaceuticals and Alpharma sign definitive merger agreement

King Pharmaceuticals, Inc. and Alpharma Inc. have announced that the two companies have signed a definitive merger agreement under which King will acquire all of the outstanding shares of Class A Common Stock of Alpharma for $37.00 per share in cash for a total equity value of approximately $1.6 billion.

24 Nov 2008

Chronic News and Research

No benefit from nifedipine widely used to prevent premature births

Peregrine Pharmaceuticals awarded U.S. patent for anti-viral applications of phospholipid-targeting antibodies

Discovery may lead to new therapeutic approaches for pain reduction

Call for greater caution in prescribing inhaled corticosteroids to COPD sufferers

New advance in the treatment of sickle cell anaemia

CardioVascular BioTherapeutics doses first patient in trial for severe coronary heart disease

Febuxostat recommended by panel for treatment of hyperuricemia in patients with gout

Patients with severe traumatic brain injuries can relearn social communication skills

MorphoSys granted U.S. patent on antibodies against GM-CSF to treat inflammatory disorders

FDA approves lung analysis software from VIDA Diagnostics

Telephone counseling may be as effective as face-to-face counseling in weight loss maintenance

Double-balloon enteroscopy offers cost-effective approach for obscure GI bleeding

Discovery of novel drug target for chronic lymphocytic leukemia

Ustekinumab receives positive opinion in Europe for treatment of plaque psoriasis

Medarex starts phase 1b clinical trial with MDX-1106 for the treatment of cancer

King Pharmaceuticals and Alpharma sign definitive merger agreement

Should the private sector play a greater role in delivering health care in low-income countries?

Humoral immunity in kidney transplantation

Children with sickle cell disease have inadequate healthcare

Nplate receives positive opinion for marketing authorisation in Europe

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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