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Enzyme caspase-8 controls apoptosis, necroptosis and pyroptosis

The enzyme caspase-8 induces a molecular cell death programme called pyroptosis without involving its enzymatic activity, a new study by Hamid Kashkar published in Nature shows.

26 Nov 2019

How the digital age impacts longevity and lifestyle?

Have you ever wondered how does the digital age affect our longevity? What effect new technologies and knowledge advances have on our life?

22 Nov 2019

Scientists investigate the dynamics of molecular changes in gliomas

Until relatively recently, cancer was viewed as a single disease with sub-types based on where in the body it arose.

22 Nov 2019

Doughnut-shaped circles of ecDNA provide tumor cells with a malignant twist

Deoxyribonucleic acid or DNA encodes information, not only in its sequence but also in its shape.

21 Nov 2019

Researchers develop breakthrough in marine sponge cell culture

Vertebrate, insect, and plant cell lines are important tools for research in many disciplines, including human health, evolutionary and developmental biology, agriculture and toxicology. Cell lines have been established for many organisms, including freshwater and terrestrial invertebrates.

21 Nov 2019

Circular DNA found in cancer cells supports their survival and resistance

A new study uncovers the role of the circular, 3D shape of extrachromosomal DNA in augmenting mutant oncogenes in cancer cells.

20 Nov 2019

Lab Innovations 2019 achieves record breaking numbers

Lab Innovations celebrated its 8th edition on 30 & 31 October 2019, trumping all records for the event. Attracting 3,860 attendees - an impressive 24% increase on the previous year - this makes it the largest Lab Innovations to date.

From Lab Innovations 15 Nov 2019

Antibiotic Resistance Threats report highlights significant gaps and impact of federal investments

The Antibiotic Resistance Threats Report released by the U.S. Centers for Disease Prevention and Control today shows that while recent federal investments to combat antibiotic resistance have had meaningful impacts, the continued spread of infections that are not effectively treated by existing medicines pose deadly threats to patients and public health.

14 Nov 2019

Knocking out 'survival system' of cancer cells could improve effectiveness of melanoma treatment

The effectiveness of current treatments for melanoma, the deadliest form of skin cancer, could be improved by using approaches that wipe out the 'survival system' of cancer cells according to a study published in Nature Communications today.

14 Nov 2019

Rutgers researcher receives $600,000 grant to study chronic lymphocytic leukemia

Rutgers Cancer Institute of New Jersey researcher Hossein Khiabanian, PhD, has received a $600,000 Translational Award from the V Foundation for Cancer Research to study chronic lymphocytic leukemia with the aim of developing research models that may help investigators better understand how CLL cells are influenced by new therapies.

11 Nov 2019

Researchers generate reliable maps for transmission risk of Zika virus

The spread of infectious diseases such as Zika depends on many different factors. Environmental factors play a role, as do socioeconomic factors. Recently, several attempts have be made to predict the transmission risk of the Zika virus at a global and local level, but the spatial and temporal patterns of transmission are still not well understood.

11 Nov 2019

Methotrexate appears to facilitate bone remodeling in patients with osteoarthritis

According to new research findings presented at the 2019 ACR/ARP Annual Meeting, methotrexate did not demonstrate superior efficacy over placebo for pain relief and function evolution at three and 12 months in patients with erosive hand osteoarthritis.

11 Nov 2019

Genetic diversity impacts efficacy of cancer immunotherapy

The constant battle against infectious pathogens has had a decisive influence on the human immune system over the course of our evolution.

8 Nov 2019

Cytel expands its advanced real-world analytics capabilities with acquisition of MTEK Sciences

Cytel Inc., the leading provider of innovative analytical software and consulting services to the biopharmaceutical sector, and a portfolio company of New Mountain Capital, today announced that it has acquired MTEK Sciences to further expand its advanced real-world analytics capabilities.

From Cytel 8 Nov 2019

Researchers reveal non-image light sensing mechanism of circadian neurons using fruit flies

University of California, Irvine researchers reveal how an ancient flavoprotein response to ultra violet (UV), blue and red light informs internal circadian processes about the time of day.

7 Nov 2019

New strain of HIV discovered and sequenced

Researchers have for the first time in twenty years come upon a new strain of HIV or Human Immunodeficiency Virus. This strain is a part of the Group M type of HIV-1. HIV-1 is the causative agent of worldwide HIV infections.

7 Nov 2019

New bacteria-killing toxin shows promise to impact superbug infectious diseases

An international research collaboration has discovered a new bacteria-killing toxin that shows promise of impacting superbug infectious diseases.

6 Nov 2019

Current ecology, not ancestral dispersal patterns, impacts the severity of menopause symptoms

A recent theory states that women enter menopause at different ages and have varying extents of symptoms due in part to residence patterns after marriage--or whether couples disperse to live with paternal or maternal kin.

6 Nov 2019

Study sheds light on a significant era in the Levant history

Who exactly were the Aurignacians, who lived in the Levant 40,000 years ago?

6 Nov 2019

Innovative research network marks a new era of radiotherapy research in the UK

The UK will be transformed into a global hub for radiotherapy research, pioneering the use of the latest techniques such as FLASH radiotherapy and artificial intelligence, with a new £56 million research network announced by Cancer Research UK today (Monday).

4 Nov 2019