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Better understanding of immune response to HIV infection

The "exhaustion" of immune cells that target HIV appears to result from chronic exposure to the virus, specifically exposure to the particular protein segments targeted by the pathogen-killing HIV-specific CD8 T cells.

6 May 2008

Newspapers examine issues related to health care proposals of Presidential candidates

Several newspapers recently published articles that examined the health care proposals of presidential candidates Sens. Hillary Rodham Clinton (D-N.Y), Barack Obama (D-Ill.) and John McCain (R-Ariz.).

6 May 2008

Botulinum toxin is safe and effective for treating cervical dystonia

New guidelines developed by the American Academy of Neurology confirm that the drug botulinum toxin is safe and effective for treating cervical dystonia, a condition of involuntary head tilt or neck movement, spasticity and other forms of muscle overactivity that interfere with movement in adults and children with an upper motor neuron syndrome, and excessive sweating of the armpits and hands.

5 May 2008

Short arms and legs could mean greater dementia risk

People with shorter arms and legs may be at a higher risk for developing dementia later in life compared to people with longer arms and legs, according to a study published in the May 6, 2008, bonus issue of Neurology, the medical journal of the American Academy of Neurology.

5 May 2008

Kidney disease substantially worsens in a fourth of African Americans despite therapy for hypertension

The best available treatment for chronic kidney disease from high blood pressure did not keep the disease from substantially worsening in about a fourth of African-Americans studied, according to long-term results of a National Institutes of Health study published April 28, 2008, in the Archives of Internal Medicine.

5 May 2008

Results of St. Jude Medical deep brain stimulation study presented at APA meeting

St. Jude Medical, Inc. today announced pilot study results from the first multi-center study investigating deep brain stimulation (DBS) of Brodmann Area 25 for major depressive disorder.

5 May 2008

New SCHIP enrollees have unmet health care needs

Even with prior private health insurance, patients enrolling in the state children's health insurance program (SCHIP) had unmet health care needs. Instituting a waiting period would further prolong these children's need to address asthma and other chronic health conditions.

5 May 2008

Analysis of alcoholics' brains suggests treatment target

An analysis of brain tissue samples from chronic alcoholics reveals changes that occur at the molecular level in alcohol abuse - and suggests a potential treatment target, according to researchers from Wake Forest University School of Medicine.

2 May 2008

Antidepressant amitriptyline shown to alleviate symptoms of irritable bowel syndrome

Researchers at Mattel Children's Hospital UCLA have found that low-dose antidepressant therapy can significantly improve the overall quality of life for adolescents suffering from irritable bowel syndrome (IBS).

1 May 2008

Children more vulnerable to harmful effects of lead at age 6 than as toddlers

Contrary to prevailing assumptions, children are more vulnerable to the harmful effects of lead exposure at the age of 6 than they are in early childhood, according to a Cincinnati Children's Hospital Medical Center study to be presented May 4 at the annual meeting of the Pediatric Academic Societies in Honolulu.

30 Apr 2008

Turning on cell-cell communication wipes out staph biofilms

University of Iowa researchers have succeeded in wiping out established biofilms of Staphylococcus aureus (staph) by hijacking one of the bacteria's own regulatory systems.

30 Apr 2008

AstraZeneca submits sNDA for SYMBICORT in chronic obstructive pulmonary disease

AstraZeneca today announced that it submitted a supplemental New Drug Application (sNDA) to the U.S. Food and Drug Administration (FDA) for approval of a new indication for SYMBICORT (budesonide/formoterol fumarate dihydrate) Inhalation Aerosol for the treatment of patients with Chronic Obstructive Pulmonary Disease (COPD). SYMBICORT is currently approved for the long-term maintenance treatment of asthma in patients 12 years and older.

30 Apr 2008

Discovery of quick method for making human monoclonal antibodies against flu

Human monoclonal antibodies (mAbs) - highly specific, identical, infection-fighting proteins produced in large quantities in the lab in cell lines that are derived from a single antibody-producing cell - against influenza can be rapidly produced in the lab, according to a new report from scientists supported by the National Institutes of Health (NIH).

30 Apr 2008

Arsenic in baby rice puts children at risk

In what will be of great concern to many parents, scientists who have carried out a survey of arsenic levels in three common brands of rice-based baby foods say they have found that arsenic levels in the foods are too high.

30 Apr 2008

McCain promotes health care proposal at Miami Children's Hospital

Presumptive Republican presidential nominee Sen. John McCain (Ariz.) on Monday at the Miami Children's Hospital promoted his health care proposal, which he said would "put families in charge," USA Today reports (Jackson, USA Today, 4/29).

29 Apr 2008

FDA approves Amitiza for irritable bowel syndrome with constipation

The U.S. Food and Drug Administration today approved Amitiza (lubiprostone) for the treatment of Irritable Bowel Syndrome with Constipation (IBS-C) in adult women aged 18 and over.

29 Apr 2008

Ranibizumab therapy for diabetic eye disease shows promise

A JDRF collaboration between Johns Hopkins researchers and Genentech has shown that a drug for the treatment of diabetic eye disease has performed better in clinical trials than the current standard treatment using laser surgery.

29 Apr 2008

New less traumatic way of delivering surfactant to help preemies breathe could reduce chronic lung disease

A less traumatic way of delivering surfactant, a lung lubricant that premature babies need to help them breathe, could reduce the incidence of respiratory problems they'll have later, Medical College of Georgia physicians say.

29 Apr 2008

Deep brain stimulation may help people with treatment resistant major depression

Researchers from the Cleveland Clinic, Brown University, and Massachusetts General Hospital will present results of a long-term outcome study that builds on previous promising research, which has shown that deep brain stimulation (DBS) is a potentially effective treatment option for people with treatment resistant major depression.

29 Apr 2008

Biomarkers identified for idiopathic pulmonary fibrosis

The first evidence of a distinctive protein signature that could help to transform the diagnosis and improve the monitoring of the devastating lung disease idiopathic pulmonary fibrosis (IPF) is being reported by University of Pittsburgh School of Medicine researchers in this month's edition of PLoS Medicine, an open-access journal of the Public Library of Science.

28 Apr 2008