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Discovery of possible target for prevention and treatment of pneumonia

Researchers at Children's Hospital of Pittsburgh of UPMC have identified a key protein target that may be a crucial factor in the development of a vaccine to prevent and new therapies to treat pneumonia, the leading killer of children worldwide.

12 Feb 2008

Discovery of cellular mechanisms that lead to in insulin resistance in diabetics

Researchers at the Swedish medical university Karolinska Institutet have in collaboration with researchers from Finland, China, Japan and the US discovered new cellular mechanisms that lead to in insulin resistance in people with diabetes.

11 Feb 2008

WHO warns of one billion death toll from tobacco

The World Health Organisation (WHO) has issued a stark warning about smoking saying that unless urgent action is taken, by the year 2100 tobacco could kill one billion people.

11 Feb 2008

Team approach to treating depression cuts medical costs

A team approach to treating depression in older adults, already shown to improve health, can also cut total health-care costs, according to a new study led by the University of Washington.

8 Feb 2008

Potential new therapy for lung disease patients

A new study by researchers at Northwestern University's Feinberg School of Medicine may change current thinking about how best to treat patients in respiratory distress in hospital intensive care units.

8 Feb 2008

Amantadine and rimantadine for influenza A in children and the elderly

The antiviral drug amantadine can prevent some cases of influenza in children, and the related medication rimantadine can reduce fever in youngsters who have the flu, according to a new review of evidence.

8 Feb 2008

Discovery of new cellular mechanisms that lead to in insulin resistance in people with diabetes

8 Feb 2008

Hot flashes may be getting an unfair rap for disrupting women's sleep at midlife

Studies have often reported that sleep problems increase during the transition into menopause, reinforcing the idea that hot flashes are to blame. But even under controlled conditions in sleep laboratories, the connection between hot flashes and sleep disruption remains unclear, reports the February 2008 issue of Harvard Women's Health Watch.

8 Feb 2008

Faith-based health program expands, adds Latino classes

A nationally-recognized, faith-based physical activity and health promotion program that helps individuals adopt healthy lifestyles and manage chronic diseases is re-launching and extending its services to the African American and Latino communities in Monroe County.

8 Feb 2008

Seniors more likely to deny smoking when asked

More elderly adults are lighting up cigarettes and not reporting their nicotine habits to doctors and others, according to findings from one of the first studies to examine the accuracy of self-reported smoking habits by age, race and gender of adults 18 years and older by researchers at the Case Western Reserve University School of Dental Medicine and other university collaborators.

8 Feb 2008

Whole grain diets lower risk of diabetes and cardiovascular disease

Diets with high amounts of whole grains may help achieve significant weight loss, and also reduce the risk of chronic diseases such as diabetes and cardiovascular disease, according to a team of Penn State researchers at University Park and the College of Medicine.

7 Feb 2008

Regular use of marijuana increases risk for gum disease

Regular use of marijuana (cannabis) in young adulthood is associated with periodontal (gum) disease, according to a study in the February 6 issue of JAMA.

7 Feb 2008

Novel small molecule therapy shows benefit for anemic patients via hydration of red blood cells

Researchers are identifying innovative therapeutics for sickle cell anemia that focus on specific factors in the disease's progression, such as the important role of hydration of the red blood cells.

7 Feb 2008

Mayo Clinic Proceedings contributors discuss impact of donor organ allocation system

Liver transplant is a life saving treatment option for people with end-stage liver disease.

7 Feb 2008

Impact of electronic personal health record on hypertension under study

Whether patients with an electronic handle on their health are more successful at beating one of the nation's leading chronic diseases is under study.

7 Feb 2008

Brain disturbances in chronic pain

People with unrelenting pain don't only suffer from the non-stop sensation of throbbing pain.

7 Feb 2008

Scientists gain new understanding of gut bugs

Scientists have made a major step towards understanding precisely which bugs in the gut are involved in which processes in the body, by mapping the different species of bugs living in seven members of the same Chinese family.

7 Feb 2008

Enbrel shown to significantly reduced levels of C-reactive protein

Amgen and Wyeth Pharmaceuticals, a division of Wyeth have announced findings from a retrospective analysis, which demonstrated that ENBREL reduced C-reactive protein (CRP), a marker of inflammation, in patients with moderate to severe plaque psoriasis following 12 weeks of treatment. Median reduction in CRP levels was 10 times greater in the ENBREL treated group compared to the placebo treated group.

5 Feb 2008

Genetic mutations in the Toll-like receptor 4 gene increase risk of preterm birth

Genetic mutations in the Toll-like receptor 4 (TLR4) gene appear to have significant association with inflammatory injury to the placenta and developing baby, researchers from the University of Pittsburgh's department of obstetrics, gynecology and reproductive sciences report at the 28th annual meeting of the Society for Maternal-Fetal Medicine.

5 Feb 2008

Novel drug romiplostim significantly improves treatment of dangerous blood disorder

Two clinical trials of the novel drug romiplostim (Nplate) show that it significantly improved platelet levels in patients with chronic immune thrombocytopenic purpura (ITP), a hematologic disorder that can cause uncontrolled bleeding.

5 Feb 2008