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GSK receives FDA 'not approvable letter' for Advair for COPD

GlaxoSmithKline has announced that the U.S. Food and Drug Administration (FDA) has issued a not approvable letter for the supplemental drug application for the 500/50 strength of Advair Diskus (fluticasone propionate and salmeterol inhalation powder) in the treatment of patients with chronic obstructive pulmonary disease (COPD).

9 Aug 2007

Voluntary exercise induces sex-specific physiological cardiac remodeling

While cardiovascular disease occurs in both men and women, it does not affect them in the same way.

9 Aug 2007

Breast implant surgery triples suicide risk

The results of a new study in the U.S. have prompted the researchers involved to recommend that doctors screen women before surgical breast enhancement.

8 Aug 2007

Vitamin B1 deficiency key to vascular problems for diabetic patients

Researchers at Warwick Medical School, University of Warwick, have discovered that deficiency of thiamine - vitamin B1 - may be key to a range of vascular problems for people with diabetes.

8 Aug 2007

New Canadian partnership enhances diabetes education and research

An innovative new partnership between the University Health Network and the University of Toronto's Banting & Best Diabetes Centre will enhance diabetes education, research and patient care and expand the search for a cure.

8 Aug 2007

Bcl-3 protein regulates inflammation by blocking ubiquitination

Researchers at the University of Pennsylvania School of Medicine recently identified how a regulatory protein called Bcl-3 helps to control the body's inflammation response to infection by interfering a critical biochemical process called ubiquitination.

8 Aug 2007

Geriatric conditions and disability

A broad study of adults ages 65 and older has found that half of them have one or more conditions that can affect their ability to participate in activities of daily living, such as bathing and dressing on their own.

8 Aug 2007

E. coli bacteria linked to Crohn's disease

A team of Cornell University scientists from the College of Veterinary Medicine, Weill Cornell Medical College and the College of Agriculture and Life Sciences have discovered that a novel group of E. coli bacteria, containing genes similar to those described in uropathogenic and avian pathogenic E. coli and enteropathogenic bacteria such as salmonella, cholera, bubonic plague, is associated with intestinal inflammation in patients with Crohn's disease in their research paper published July 12 by the ISME Journal: Multidisciplinary Journal of Microbial Ecology.

8 Aug 2007

Health plan interventions control prescription drug expenditures

As national spending on prescription drugs rose faster than any other segment of health care spending, the health plan at Wake Forest University Baptist Medical Center was able to maintain constant spending, resulting in savings of more than $6.6 million over three years.

8 Aug 2007

Perk up the memory girls with three cups of coffee a day!

A new study has found that drinking more than three cups of coffee a day may helped protect older women's memories.

7 Aug 2007

New drugs to combat bioterrorism

The University of Illinois at Chicago College of Pharmacy has received a grant from the U.S. Department of Defense to develop new drugs to combat agents of bioterrorism.

7 Aug 2007

Maternal obesity and birth defects

Mothers of babies born with some structural birth defectsincluding missing limbs, malformed hearts and underdeveloped spinal cordsappear more likely to be obese prior to becoming pregnant than mothers whose children are born without such defects, according to a report in the August issue of Archives of Pediatrics & Adolescent Medicine, one of the JAMA/Archives journals.

7 Aug 2007

Inhaled nitric oxide safe for very premature infants

A nationwide study led by researchers at UCSF provides evidence that inhaled nitric oxide is safe and effective for the prevention of the most common type of long-term lung disease of very premature infants.

7 Aug 2007

Caffeine may help older women protect their thinking skills

Caffeine may help older women protect their thinking skills, according to a study published in the August 7, 2007, issue of Neurology ®, the medical journal of the American Academy of Neurology.

7 Aug 2007

Electrical device partly restores sense of balance in animals

Hearing and balance experts at Johns Hopkins report successful testing in animals of an electrical device that partly restores a damaged or impaired sense of balance.

7 Aug 2007

What causes rosacea?

Doctors can describe the symptoms of rosacea, a common inflammatory skin disease that causes facial redness and affects nearly 14 million Americans.

6 Aug 2007

Life around newborn discharge

A landmark nationwide study, published in the journal Pediatrics, is the first ever to prospectively examine the decision-making process of over 4,000 mothers and their physicians around the readiness of mothers and their infants to leave the hospital after childbirth.

6 Aug 2007