Chronic News and Research

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Infliximab fails to improve chronic obstructive pulmonary disease symptoms

A promising anti-inflammatory drug failed to improve symptoms of moderate to severe chronic obstructive pulmonary disease, or COPD, in a large, multi-center trial.

2 May 2007

Scientists discover way to distinguish pancreatic cancer from non-cancerous tissue

The research examined pancreatic cancer cells for tiny molecules called microRNA (miRNA). It shows that relative levels of certain miRNAs can distinguish pancreatic cancer from nearby noncancerous tissue and from inflamed pancreatic tissue.

2 May 2007

Ohioans spend $62.2 billion on non-institutional health care each year

...while the Ohio economy loses between $2.1 and $5.8 billion due to lost productivity and other indirect costs of having 1.3 million Ohio residents without health insurance, according to research released today by the Health Policy Institute of Ohio (HPIO).

2 May 2007

New treatments have major impact on heart failure rates

Deaths from severe heart attacks following admission to hospital have nearly halved in six years as a result of advances in medical treatment.

2 May 2007

Statin drugs also may help reduce risk of heart failure

Statin drugs, known primarily for their ability to lower cholesterol, also may reduce the overactive sympathetic nervous system response that contributes to the worsening of heart failure and increases the risk of sudden cardiac death, two University of Missouri-Columbia researchers have found. Heart failure is the leading cause of morbidity and mortality in the United States.

2 May 2007

Expression pattern of microRNA may be useful in differentiating between chronic pancreatitis and pancreatic cancer

Pancreatic cancer is a lethal disease, with the annual deaths nearly equaling the incidence of 33,000 in the United States, according to background information in the article.

2 May 2007

Liver stiffness indicates severe portal hypertension in patients with hepatitis C-related cirrhosis

Measuring liver stiffness using transient elastography can predict severe portal hypertension in patients with hepatitis C-related cirrhosis, according to a new study in the May issue of Hepatology, the official journal of the American Association for the Study of Liver Diseases (AASLD).

2 May 2007

Adverse health outcomes after Hurricane Katrina among children and adolescents with chronic conditions

Children and teenagers in New Orleans with chronic medical conditions at the time of Hurricane Katrina were more likely than other children to have worsening of physical and psychological symptoms, develop new symptoms, miss doctor appointments and run out of medications in the wake of the disaster.

2 May 2007

Biomarker discovery bodes well for better cancer diagnostics

While new findings from Ohio State University scientists suggest a genetic marker that could help distinguish between chronic pancreatitis and pancreatic cancer and gauge who will do well with cancer treatment, a pharmacologist at the Kimmel Cancer Center at Jefferson in Philadelphia sees the discovery as much more.

2 May 2007

FDA advisory committee supports Advair 500/50 in reducing COPD exacerbations

An Advisory Committee to the Food and Drug Administration (FDA) has unanimously agreed that GlaxoSmithKline's Advair Diskus 500/50 (fluticasone propionate and salmeterol inhalation powder) demonstrated a significant reduction in the risk of exacerbations in patients with chronic obstructive pulmonary disease (COPD), the fourth leading cause of death in the U.S.

2 May 2007

Unstable leukemia stem cells may predispose patients to drug resistance

The BCR-ABL gene in chronic myeloid leukemia stem cells has a tendency to quickly mutate, and this may help explain why patients are predisposed to resistance to drugs like imatinib that target that gene, according to a study in the May 2 Journal of the National Cancer Institute.

2 May 2007

Why do some people get fat even when they eat relatively little?

What creates that irresistible urge for a bag of potato chips or a hunk of chocolate cake, as opposed to a nice crisp apple? Can food urges be irresistible?

2 May 2007

Top 10 diseases by cost

Bladder, prostate and other urinary tract diseases cost Americans nearly $11 billion a year, according to a new report from the National Institutes of Health.

2 May 2007

Chronic fatigue syndrome impairs sleep and homeostatic response

Chronic fatigue syndrome (CFS) has been associated with altered amounts of slow wave sleep, which could reflect reduced electroencephalograph (EEG) activity and impaired sleep regulation.

2 May 2007

A mobile medical care approach targeting underserved populations in post-hurricane Katrina Mississippi

They packed what they needed for a disaster - equipment for trauma treatment and IV fluids - and headed south to Mississippi.

2 May 2007

Early dental visits decrease kid's tooth decay

The American Academy of Pediatric Dentistry (AAPD), the recognized leader in children's oral health, continues to emphasize that the way to decrease children's tooth decay is by visiting a dentist early on.

2 May 2007

Teenagers who suffer migraines at risk of suicide

Researchers in Taiwan say teens who suffer from migraine headaches on a daily basis, are at greater risk for suicide than teens who don't have migraines.

2 May 2007

Mechanisms of glucose homeostasis and early diabetes

Glucose homeostasis, the appropriate balancing of blood sugar levels, is impaired early in patients who become diabetic, causing life-threatening complications such as kidney failure and heart attacks.

1 May 2007

Teens who have chronic daily headaches are at greater risk for suicide

Teens who have chronic daily headache, especially those with migraine headaches, are at greater risk for suicide than teens who don't have migraines, according to a study published in the May 1, 2007, issue of Neurology, the scientific journal of the American Academy of Neurology.

1 May 2007

More chronically ill children dying in intensive care

The proportion of chronically ill young children dying in intensive care after being admitted to other hospital wards has steadily risen year on year since the end of the 1990s, reveals a study in the Journal of Medical Ethics.

1 May 2007