Neurosurgery News and Research

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Neurologix announces positive interim results of gene therapy clinical trial for patients with Parkinson's disease

Neurologix has announced positive interim results of its landmark gene therapy clinical trial for patients with Parkinson's disease. Neurologix's 12-patient, dose-escalating Phase I trial is the world's first study to use a viral vector (the non-pathogenic adeno-associated virus, or AAV) for the treatment of an adult neurological disease.

26 Sep 2005

First clinical guidelines to help improve the diagnosis and treatment of people with normal pressure hydrocephalus

An international team of medical experts led by a Virginia Commonwealth University researcher has established the first clinical guidelines to help improve the diagnosis and treatment of people with normal pressure hydrocephalus, a debilitating condition in the brain that often goes undiagnosed or is misdiagnosed as Alzheimer's or Parkinson's disease.

21 Sep 2005

Release of the neurotransmitter GABA halts stem cell production in the brain

Release of the neurotransmitter GABA by adult neuronal precursor cells that develop into neurons limits stem cell proliferation, according to a study at Yale School of Medicine in the September issue of Nature Neuroscience.

1 Sep 2005

First study to test the role of RNA chemical modifications on immunity

The investigators published their findings in the August issue of Immunity. "We think this study will open a new area of research in understanding how our immune systems protect us," says Weissman.

23 Aug 2005

Study estimates Staphylococcus aureus infections cause 12,000 deaths, cost hospitals $9.5 billion

Staphylococcus aureus infections (S. aureus) create an enormous burden to hospitals by significantly increasing costs, length of patient stays and mortality rates, a Northwestern Memorial Hospital researcher found in the most comprehensive study to date, published today's Archives of Internal Medicine.

10 Aug 2005

Rush to offer new treatment for arterio-venous malformations

Rush University Medical Center will be the first in Chicago and among the first hospitals in the nation to offer a promising new treatment for arterio-venous malformations (AVMs) following its approval by the FDA on July 21.

26 Jul 2005

Alfred biomodelling creates life like hobbit

Pioneering Alfred technology is being put to good use in understanding where we come from, in the fields of Anthropology and Palaeontology.

26 Jul 2005

British holiday maker dies of rabies after dog bite in Goa

Health officials in the UK have confirmed that a woman who was bitten by a dog on her holiday in Goa, India, has died from rabies.

23 Jul 2005

Vagal nerve stimulation, an innovative therapy for depression

The Saint Louis University Health Sciences Center medical team involved in the research and development of an innovative therapy for depression - vagal nerve stimulation (VNS) - is starting a new clinic for patients who have treatment-resistant depression.

19 Jul 2005

New drug to treat stroke complications tested in US for the first time as part of an international trial

A Roanoke, Va. woman is the first U. S. participant in an international, multi center trial of a new drug that shows promise in treating complications from a stroke.

1 Jul 2005

Chemotherapy for brain tumors is boosted after vaccine targets resistance-related TRP-2 antigen

In the August issue of the journal Oncogene, researchers at Cedars-Sinai Medical Center's Maxine Dunitz Neurosurgical Institute describe a molecular mechanism that appears to make malignant brain tumors more vulnerable to chemotherapy after they have been treated with the dendritic cell vaccine.

13 Jun 2005

Doctors study surgery to stop epileptic seizures

Melinda Hillyard of Winchester, Va., first had epileptic seizures when she was eight years old. The seizures went away for years, then returned after the birth of her first child. "I never knew when my world would turn upside down," she recalled.

6 Jun 2005

1980's brain surgery may have exposed 50 patients to Creutzfeldt-Jakob Disease

It has now been revealed that as many as 50 patients may have been exposed to Creutzfeldt-Jakob Disease (CJD) following brain surgery during the 1980s.

31 May 2005

Fluorescence device to diagnose atherosclerosis and tumors

In a presentation at the Conference on Lasers and Electro-Optics (CLEO), researchers from Cedars-Sinai Medical Center's Biophotonics Research and Technology Development Laboratory described recent progress on a device that stimulates, collects and measures light emissions from body tissues to diagnose critical atherosclerotic plaques (vulnerable plaques) and aggressive brain tumors.

29 May 2005

Practice of defensive medicine widespread among physicians in specialties at high risk of lawsuits

More than 90 percent of surveyed physicians in Pennsylvania reported defensive medicine practices such as over-ordering of diagnostic tests, unnecessary referrals and avoidance of high-risk patients, according to a study in the June 1 issue of JAMA.

25 May 2005

Medical Research Council funds research to look at cannabis based medicines in multiple sclerosis treatment

A trial to determine whether cannabis-based medicines can reduce disability in patients with multiple sclerosis (MS) has been funded by the Medical Research Council (MRC).

24 May 2005

British surgeons remove part of a woman's brain to cure her epilepsy

Helen Hollis, 41, from Teversal, near Mansfield, Nottingham, a former nurse and the mother of two, had her first seizure aged 19, but had to wait years before her condition was diagnosed.

23 May 2005

The brain damage wrought by a minor stroke can alter the way artists paint

The study reports on two professional painters, both of whom had a stroke, located in the left occipital lobe of the brain and limbic thalamus, respectively.

17 May 2005

Virus that targets and kills glioblastoma

Yale School of Medicine scientists have identified a virus that targets and kills glioblastoma, a deadly type of human brain tumor resistant to current medical or surgical treatment, according to a study published as the cover article in the Journal of Virology.

11 May 2005

Glucose byproduct prevents brain damage after diabetic coma

A natural, non-toxic byproduct of glucose may prevent brain cell death and cognitive impairment in diabetics following an episode of severely low blood sugar, according to researchers at the San Francisco VA Medical Center (SFVAMC).

4 May 2005