Small Intestine News and Research

RSS

Study shows how interactions between microbiome and the immune system contribute to liver disease

A new study by researchers in the Quadram Institute has provided insights into how interactions between gut microbes and cells of the immune system contribute to cholestatic liver disease.

20 Apr 2020

New study raises red flags about strategy to block cancer drug resistance

Sooner or later, most cancer patients develop resistance to the very chemotherapy drugs designed to kill their cancer, forcing oncologists to seek alternatives.

17 Apr 2020

New therapeutic approach for preserving inflammation-free phases of Crohn's disease

Intestinal stem cell metabolism is facilitated by mitochondria - the in-cell power plants. Chronic inflammation processes inhibit the cells' metabolism and lead to functional loss of these stem cells.

15 Apr 2020

Alzheimer's patients may need modified dosing regimens for selected drugs

Patients with Alzheimer's disease are often prescribed drugs for other conditions -- including diabetes or high blood pressure -- at the same doses as those without dementia.

15 Apr 2020

Bacterial metabolism of bile acids boosts generation of immune cells, study shows

A Ludwig Cancer Research study has discovered a novel means by which bacterial colonies in the small intestine support the generation of regulatory T cells--immune cells that suppress autoimmune reactions and inflammation.

15 Apr 2020

Cats, ferrets more vulnerable to COVID-19 than dogs

A recent Chinese study published on the preprint server BioRxiv finds that cats and ferrets appear to be extremely vulnerable to the virus, but dogs, pigs, and poultry do not seem to contract it. As preprints, papers are not yet peer-reviewed, undergoing only basic scientific screening.

12 Apr 2020

Research shows entire brain responds to the gut through neuronal connections

You know that feeling in your gut? We think of it as an innate intuition that sparks deep in the belly and helps guide our actions, if we let it. It's also a metaphor for what scientists call the "gut-brain axis," a biological reality in which the gut and its microbial inhabitants send signals to the brain, and vice versa.

2 Apr 2020

How (easily) does the novel coronavirus spread?

Viruses are tiny bundles of DNA or RNA which have the ability to infect host cells, hijack the machinery of the host cell and then replicate. Once the host cell’s resources are exhausted, the viral particles are released to infect other cells. In this way, the viruses ensure their survival, often at the expense of the host.

1 Apr 2020

Revita DMR therapy has potential to transform lives of patients with poorly controlled type 2 diabetes

Patients with poorly controlled type 2 diabetes who underwent a novel, minimally invasive, endoscopic procedure called Revita duodenal mucosal resurfacing had significantly improved blood glucose (sugar) levels, liver insulin sensitivity, and other metabolic measures three months later, according to new data from the REVITA-2 study.

30 Mar 2020

Scientists uncover key molecular mechanism underlying different aspects of sepsis

Sepsis is a life-threatening condition that kills millions annually; it is poorly understood and has no specific treatment.

27 Mar 2020

Ulcerative colitis and a missing microbe in the gut

Ulcerative colitis is a seriously debilitating inflammatory disease of the bowel leading to crippling symptoms that can affect the quality of life severely. Researchers from Stanford University School of Medicine have found in a new study that a missing microbe could be linked to this condition. The study was published today in the latest issue of the journal Cell Host & Microbe.

25 Feb 2020

Gut bacteria may predict risk of pulmonary hypertension

A team of researchers has found that the microflora of bacteria within the gut of humans could be a contributor to the development of pulmonary arterial hypertension (PAH). The study titled, "Altered Gut Microbiome Profile in Patients With Pulmonary Arterial Hypertension," in the latest issue of the American Heart Association's journal Hypertension.

24 Feb 2020

Relapse is common for bariatric surgery patients who quit smoking

Although 1 in 7 adults smoke cigarettes the year prior to undergoing weight-loss surgery, nearly all successfully quit at least a month before their operation.

23 Feb 2020

New Endothelial Cell Atlas can be used to improve treatments for many diseases

New surprising knowledge on endothelial cells in a dozen different murine tissues is now available in an open access, user-friendly, database for professionals.

20 Feb 2020

Combination of green tea extract and exercise mitigates fatty liver disease in mice

The combination of green tea extract and exercise reduced the severity of obesity-related fatty liver disease by 75% in mice fed a high-fat diet, according to Penn State researchers, whose recent study may point to a potential health strategy for people.

16 Feb 2020

Lab mice may have differences in small-intestine microbiome as compared to humans

There is a growing consensus that the gut microbiome is involved in many aspects of physical and mental health, including the onset of Parkinson's disease, multiple sclerosis, and even some behaviors.

14 Feb 2020

Bariatric surgeries may change patients' sensitivity to and absorption of alcohol

A new study of 55 women found that two of the most popular forms of bariatric surgery - Roux-en-Y gastric bypass and laparoscopic sleeve gastrectomy - may dramatically change patients' sensitivity to and absorption of alcohol.

14 Feb 2020

UChicago researchers develop first accurate mouse model of celiac disease

Researchers at the University of Chicago have developed the first truly accurate mouse model of celiac disease. The animals have the same genetic and immune system characteristics as humans who develop celiac after eating gluten. This provides a vital research tool for developing and testing new treatments for the disease.

12 Feb 2020

Research opens the door to healthier white bread

Group identifies the parts of the wheat genome that control fiber content of white flour – raises hope that products will be in supermarkets within five years.

31 Jan 2020

Study shows superior functionality of Duodenum Intestine-Chip populated with organoids

Emulate, Inc. announced today a published study in collaboration with Johns Hopkins University School of Medicine, that demonstrated superior functionality of the Duodenum Intestine-Chip populated with organoids, compared to organoids alone.

14 Jan 2020

Small Intestine News and Research

Study shows how interactions between microbiome and the immune system contribute to liver disease

New study raises red flags about strategy to block cancer drug resistance

New therapeutic approach for preserving inflammation-free phases of Crohn's disease

Alzheimer's patients may need modified dosing regimens for selected drugs

Bacterial metabolism of bile acids boosts generation of immune cells, study shows

Cats, ferrets more vulnerable to COVID-19 than dogs

Research shows entire brain responds to the gut through neuronal connections

How (easily) does the novel coronavirus spread?

Revita DMR therapy has potential to transform lives of patients with poorly controlled type 2 diabetes

Scientists uncover key molecular mechanism underlying different aspects of sepsis

Ulcerative colitis and a missing microbe in the gut

Gut bacteria may predict risk of pulmonary hypertension

Relapse is common for bariatric surgery patients who quit smoking

New Endothelial Cell Atlas can be used to improve treatments for many diseases

Combination of green tea extract and exercise mitigates fatty liver disease in mice

Lab mice may have differences in small-intestine microbiome as compared to humans

Bariatric surgeries may change patients' sensitivity to and absorption of alcohol

UChicago researchers develop first accurate mouse model of celiac disease

Research opens the door to healthier white bread

Study shows superior functionality of Duodenum Intestine-Chip populated with organoids

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Latest News