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Transcription factor promotes stem cell proliferation to repair tissue damage

The master regulator of muscle differentiation, MyoD, functions early in myogenesis to help stem cells proliferate in response to muscle injury, according to researchers at Case Western Reserve University. The study appears online Jan. 4 in the Journal of Cell Biology (www.jcb.org).

5 Jan 2010

E2F1 transcription factor inhibition reduces EGFR expression and invasive potential of melanoma cells

Inhibition of transcription factor E2F1 reduced epidermal growth factor receptor (EGFR) expression and reduced the invasive potential but not proliferation of metastatic melanoma cells, according to a brief communication published online December 23 in the Journal of the National Cancer Institute.

24 Dec 2009

Elizabethtown DI exceeds standard performance markers set by the RBMA

Opening day for any business is generally a nerve-wracking experience. Last-minute surprises are not uncommon. For Shonna Galloway, administrator for the brand-new Elizabethtown Diagnostic Imaging, however, the day before her employer's grand opening in October 2007 was one she'll never forget.

23 Dec 2009

Amarillo Endoscopy Center selects Wolters Kluwer Health's ProVation MD software

Wolters Kluwer Health, a leading global provider of information for healthcare professionals and students, announced today that Amarillo Endoscopy Center has selected its ProVation® MD software for procedure documentation and coding.

22 Dec 2009

Second wave of H1N1 virus infection in the U.S. comes to an end

Rates of 2009 H1N1 influenza virus testing in the U.S. have declined more than 75 percent since their peak in late October, suggesting that the "second wave" of virus infection that sickened tens of millions of Americans since it began four months ago may be coming to an end, according to a new report by Quest Diagnostics Incorporated, the world's leading provider of diagnostic testing, information and services.

19 Dec 2009

Influence of key transcription factor is less widespread than thought and varies over time

For decades, science texts have told a simple and straightforward story about a particular protein-a transcription factor-that helps the embryo of the fruit fly, Drosophila melanogaster, pattern tissues in a manner that depends on the levels of this factor within individual cells.

18 Dec 2009

Medifacts International announces new innovations in the use of telemedicine in clinical trials

MEDIFACTS INTERNATIONAL, INC., one of the largest global providers of noninvasive cardiovascular diagnostic services, today announced that they are once again leading the Cardiovascular Safety Services marketplace in innovation, expertise, and execution - this time with new innovations in the use of telemedicine, T-SMBP (Telemonitoring Self Measured Blood Pressure), in clinical trials.

17 Dec 2009

Genes work together by huddling in clusters inside nucleus, research reveals

Research from the Babraham Institute has revealed for the first time that genes work together by huddling in clusters inside the nucleus - the information centre of a cell. These findings, published in the online edition of the journal Nature Genetics, represent a paradigm shift in our understanding of how the genome is spatially organised in relation to gene expression.

16 Dec 2009

ARKRAY reintroduces the CLIA waived DiaScreen 50 Urine Chemistry Analyzer

ARKRAY USA, Inc., a global leader of clinical chemistry, urine chemistry, and blood glucose products, today announced that it has re-introduced the CLIA waived DiaScreen® 50 Urine Chemistry Analyzer.

15 Dec 2009

NIH awards $14.6M for Eukaryotic Pathogen Genome Database Resource expansion

Researchers from the University of Pennsylvania and the University of Georgia have been awarded a five-year, $14.6 million contract from the National Institute of Allergy and Infectious Diseases, part of the US National Institutes of Health, to expand and extend work on the Eukaryotic Pathogen Genome Database Resource, http://EuPathDB.org.

11 Dec 2009

Dermal stem cells may be useful for treating diabetic ulcers and neurological disorders

Scientists have discovered a new type of stem cell in the skin that acts surprisingly like certain stem cells found in embryos: both can generate fat, bone, cartilage, and even nerve cells.

10 Dec 2009

SU2C awards $9.68 million to support high-risk cancer research

Stand Up To Cancer (SU2C) announced today that it is awarding $9.68 million to support high-risk/high-reward cancer research conducted by 13 young scientists.

7 Dec 2009

'Twist' gene plays a key role in the development of breast cancer

Working with mice, scientists at Johns Hopkins publishing in the December issue of Neoplasia have shown that a protein made by a gene called "Twist" may be the proverbial red flag that can accurately distinguish stem cells that drive aggressive, metastatic breast cancer from other breast cancer cells.

5 Dec 2009

Body needs fasting periods to stay healthy

A body that is provided with food too often gets caught up in the maelstrom of a lack of exercise, obesity and ultimately diabetes. The trigger is a molecular switch that is controlled by insulin, a new study by scientists from ETH Zurich has revealed.

3 Dec 2009

Glutamatergic nerve cells regularly generated in the brain

Until only a few years ago, neurogenesis - the process of nerve cell development - was considered to be impossible in the adult brain. The textbooks asserted that dead nerve cells could not be replaced. Then researchers discovered regions in the forebrain in humans in which new nerve cells can be generated throughout life. These so-called GABAergic cells use gamma-aminobutyric acid (GABA), a neurotransmitter of the central nervous system.

1 Dec 2009

MedQuist signs agreement with Nuance Communications

MedQuist Inc., a leading provider of technology-enabled clinical documentation services, today announced that it has signed an agreement with Nuance Communications, Inc. (Nuance) under which MedQuist will now license Nuance's SpeechMagic speech recognition engine and processing software for use in SpeechQ of General Medicine(TM), MedQuist's front-end speech recognition application for all medical disciplines.

1 Dec 2009

Researchers uncover atomic-level action of ring-shaped protein motors

The atomic-level action of a remarkable class of ring-shaped protein motors has been uncovered by researchers with the Lawrence Berkeley National Laboratory (Berkeley Lab) using a state-of-the-art protein crystallography beamline at the Advanced Light Source (ALS).

25 Nov 2009

Health watch: When you eat just as vital to what you eat

When you eat may be just as vital to your health as what you eat, found researchers at the Salk Institute for Biological Studies. Their experiments in mice revealed that the daily waxing and waning of thousands of genes in the liver—the body's metabolic clearinghouse—is mostly controlled by food intake and not by the body's circadian clock as conventional wisdom had it.

25 Nov 2009

ProVation EHR and MD software to be implemented at North Shore Gastroenterology and Endoscopy Centers

Wolters Kluwer Health, a leading global provider of information for healthcare professionals and students, announced today that North Shore Gastroenterology and Endoscopy Centers has selected its ProVation® MD software for procedure documentation and coding, and its ProVation® EHR electronic health record and patient charting solution. The software will be used at locations in Westlake and Garfield Heights, OH.

24 Nov 2009

Scientists determine how insulin resistant drugs alter core biochemical pathways through systems biology approach

Researchers from the University of California, San Diego recently offered the sharpest-yet picture of how core biochemical pathways in skeletal muscle cells and fat cells are altered in people who suffer from insulin resistance-a primary defect in type 2 diabetes and obesity. Taking a systems biology approach, the bioengineers and medical researchers also determined how a common class of drugs for treating insulin resistance-TZDs-alter these same core pathways.

24 Nov 2009