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‘Precision Medicine’ may not always be so precise when applied to diverse populations, study says

Precision Medicine in oncology, where genetic testing is used to determine the best drugs to treat cancer patients, is not always so precise when applied to some of the world's more diverse populations, according to a study led by the Translational Genomics Research Institute, an affiliate of City of Hope, and the Keck School of Medicine of the University of Southern California.

27 Oct 2017

New enzyme may one day enable genome surgery that erases harmful mutations

DNA editing just got a sharp, new pencil. Researchers have built an enzyme that can perform a previously impossible DNA swap, directly changing the DNA base pair from an A•T to a G•C.

26 Oct 2017

Genetic variability of Helicobacter pylori complicates efforts to develop effective vaccine

Helicobacter pylori is a widespread bacterial pathogen that infects the lining of the stomach, where it can cause ulcers and even cancer. As a new study shows, its genetic variability complicates efforts to develop an effective vaccine.

25 Oct 2017

New flu forecasting tool makes better predictions by factoring evolution of virus

Each year, public health officials monitor the spread of influenza to identify which flu strains need to go into that year's vaccines and where outbreaks will occur. But it can be difficult to predict how bad a particular flu season will be until people actually start getting sick.

25 Oct 2017

Continuous EEG can be more reliable way to identify infants at risk for brain injury

Continuously recording the brain's electrical signals and examining how those impulses evolve over time is a more reliable way to identify infants at risk for brain injury, compared with doing snapshot evaluations, according to a prospective cohort study led by Children's National Health System research-clinicians.

25 Oct 2017

Research identifies molecular mechanism that causes kidney cancer to resist drug treatment

New research from The University of Texas Health Science Center at San Antonio and U.S. Department of Veterans Affairs has identified the molecular mechanism that causes kidney cancer to resist drug treatment.

25 Oct 2017

Penn researchers provide new insights into how Notch drives growth of B-cell cancers

Notch is one of the most frequently mutated genes in chronic lymphocytic leukemia (CLL), the most common leukemia in adults in the United States. It is also often mutated in other common B cell tumors, such as mantle cell lymphoma.

23 Oct 2017

New study adds evidence to ‘selfish brain’ theory of human evolution

Human brains are expensive - metabolically speaking. It takes lot of energy to run our sophisticated grey matter, and that comes at an evolutionary cost.

23 Oct 2017

Small RNA molecules trigger cancer cells to commit suicide

Small RNA molecules originally developed as a tool to study gene function trigger a mechanism hidden in every cell that forces the cell to commit suicide, reports a new Northwestern Medicine study, the first to identify molecules to trigger a fail-safe mechanism that may protect us from cancer.

19 Oct 2017

Jealousy study in pair-bonded monkeys offers insight into human emotions and behavior

It's perhaps one of the most common emotions to feel in a relationship, but one that's virtually untouched when it comes to studying relationships in monogamous primate species.

19 Oct 2017

TGen project to develop standard operating procedures for single-cell RNA sequencing

The Translational Genomics Research Institute today announced grant support from the Chan Zuckerberg Initiative donor advised fund, an advised fund of the Silicon Valley Community Foundation, that will help revolutionize how researchers identify the genetic source of diseases and how best to treat each patient.

17 Oct 2017

Genetic diversity plays major role in evolution of drug resistance

Researchers have shown that genetic diversity plays a key role in enabling drug resistance to evolve. Scientists at the Wellcome Trust Sanger Institute and the Institute for Research on Cancer and Ageing of Nice in France, show that high genetic diversity can prime new mutations that cause drug resistance.

17 Oct 2017

Researchers use new model to predict intergenerational predisposition to C-section

During the last decades, rates of Caesarean section have multiplied; by now it is one of the most frequently performed surgical treatments worldwide. Even if many of these C-sections are not strictly medically indicated, human childbirth is complicated and risky compared to that in other primates.

17 Oct 2017

Genes that determine skin color studied - new revelations

Human populations vary vastly in skin tones. European populations have been studied and some of the genes that determine skin color have been found. A latest study in a varied African population has found the specific and new genetic variants that could determine skin color and skin pigmentation. The study report is published in the journal Science.

16 Oct 2017

Breakthrough discovery reveals positive correlation between sugar and cancer

A nine-year joint research project conducted by VIB, KU Leuven and VUB has led to a crucial breakthrough in cancer research.

13 Oct 2017

Cold Spring Harbor Laboratory Press releases new book on cancer evolution

Cold Spring Harbor Laboratory Press announced the release of Cancer Evolution, available on its website in hardcover and ebook formats.

12 Oct 2017

Research finds higher rates of cancer in world's ‘better’ countries

The world's "better" countries, with greater access to healthcare, experience much higher rates of cancer incidence than the world's "worse off" countries, according to new research from the University of Adelaide.

11 Oct 2017

Change in epigenetic gene regulation by imprinting can trigger preeclampsia, study shows

Preeclampsia is the most dangerous form of hypertension during a pregnancy and can be fatal for both mother and child. Though it is known to originate in the placenta, the root causes remain largely a mystery.

6 Oct 2017

Study uses ferret model to elucidate key mechanisms for gyrus formation

The human brain is highly developed with higher functions compared to other animals, thanks to which humans are believed to have acquired special abilities. One of the important factors considered to contribute to the development of the brain is the gyrus, the fold on the cerebral cortex surface.

5 Oct 2017

Genital herpes was inherited from human ancestors

There are two main herpes simplex viruses that cause herpes in man – those that cause cold sores or HSV1 and those that cause genital herpes or HSV2. Humans and chimpanzees both were affected by HSV1 millions of years ago when their lineages split. HSV2 however did not leap on to humans until much later shows new research.

3 Oct 2017

Evolution News and Research

‘Precision Medicine’ may not always be so precise when applied to diverse populations, study says

New enzyme may one day enable genome surgery that erases harmful mutations

Genetic variability of Helicobacter pylori complicates efforts to develop effective vaccine

New flu forecasting tool makes better predictions by factoring evolution of virus

Continuous EEG can be more reliable way to identify infants at risk for brain injury

Research identifies molecular mechanism that causes kidney cancer to resist drug treatment

Penn researchers provide new insights into how Notch drives growth of B-cell cancers

New study adds evidence to ‘selfish brain’ theory of human evolution

Small RNA molecules trigger cancer cells to commit suicide

Jealousy study in pair-bonded monkeys offers insight into human emotions and behavior

TGen project to develop standard operating procedures for single-cell RNA sequencing

Genetic diversity plays major role in evolution of drug resistance

Researchers use new model to predict intergenerational predisposition to C-section

Genes that determine skin color studied - new revelations

Breakthrough discovery reveals positive correlation between sugar and cancer

Cold Spring Harbor Laboratory Press releases new book on cancer evolution

Research finds higher rates of cancer in world's ‘better’ countries

Change in epigenetic gene regulation by imprinting can trigger preeclampsia, study shows

Study uses ferret model to elucidate key mechanisms for gyrus formation

Genital herpes was inherited from human ancestors

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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