Severe Acute Respiratory News and Research

RSS

Engineered small extracellular vesicles for the neutralization of SARS-CoV-2

Characterizing these engineered sEVs, the researchers demonstrated that the soluble angiotensin-converting enzyme 2 (sACE-2) loaded sEV successfully binds and thus inhibits the entry of wild-type SARS-CoV-2 as well as its variants, protecting against SARS-CoV-2 infection. They also demonstrated the therapeutic efficacy of these engineered sEVs in vivo.

9 Jan 2022

Bolstering current therapeutic antibody treatments to help fight Omicron infections

Researchers test the neutralizing action of a panel of eight therapeutic monoclonal antibodies against the SARS-CoV-2 Omicron (B.1.1.529) variant.

9 Jan 2022

SARS-CoV-2 Omicron variant uses endosomal entry pathway and grows in upper respiratory tract cells

Researchers demonstrate that the SARS-CoV-2 Omicron variant grows rapidly in human primary nasal epithelial cultures.

9 Jan 2022

Emerging SARS-CoV-2 B.1.619 and B.1.620 variants in South Korea

Researchers investigate the spread and transmission ability of SARS-CoV-2 lineages B.1.619 and B.1.620 in South Korea.

9 Jan 2022

SARS‑CoV‑2 Omicron variant escapes monoclonal antibodies

Researchers determine the neutralizing activity of four mAbs against ten strains of SARS-CoV-2.

9 Jan 2022

Lab engineered human A549 lung cell model conducive for investigating SARS-CoV-2 antivirals

Researchers developed a human A549 lung epithelial cell-based model to probe SARS-CoV-2 replication.

9 Jan 2022

SARS-CoV-2 Omicron a product of offensive evolution with compromised antigenicity

Researchers investigate the relationship between the SARS-CoV-2 Omicron variant and immune system based on self/nonself short constituent sequences.

9 Jan 2022

Dual-receptors help widespread dissemination of SARS-CoV-2

Researchers demonstrate the role of integrins in the establishment of the SARS-CoV-2 infection.

9 Jan 2022

Study shows probiotics can reduce symptoms of COVID-19 when taken post-exposure

A new study shows how a daily use of Lactobacillus rhamnosus GG (LGG) probiotic may protect against symptom development in instances when it is used as post-exposure prophylaxis within seven days after exposure to severe acute respiratory syndrome coronavirus 2.

7 Jan 2022

Booster mRNA vaccination effective in reviving anti-SARS-CoV-2 antibody titers among the elderly

A new study found that a booster dose vaccination against COVID-19 was successful in taking binding. and neutralizing antibodies to levels higher than those observed after the initial double-dose regimen.

7 Jan 2022

Vaccine breakthrough COVID-19 infections found to be less likely transmitted

A new study displays that vaccine breakthrough COVID-19 infections are far less likely to transmit from the index patient to contacts than infections in partially or unvaccinated individuals.

7 Jan 2022

Researchers investigate SARS-CoV-2 specific inflammatory response

New research can confirm that while some of the response from monocytes to SARS-CoV-2 is generic to virus infection, most of it SARS-CoV-2 specific, especially proinflammatory responses.

7 Jan 2022

Exploring neurodevelopmental effects on infants from in-utero exposure to COVID-19

A new study aimed to determine the associations between fetal exposure to maternal SARS-CoV-2 infection, in-utero, and child neurodevelopmental status.

7 Jan 2022

Multisystem inflammatory syndrome in children rare after COVID-19 vaccination in adolescents

The current study was based on merged results using the CDD’s surveillance database coupled with the Vaccine Adverse Event Reporting System (VAERS), along with reports from health departments or physicians to the CDC.

7 Jan 2022

Reinfection with SARS-CoV-2 in children

These findings bear out earlier reports that COVID-19 is less frequent and severe in children than adults.

7 Jan 2022

SARS-CoV-2 Omicron variant leads to widespread escape from neutralizing antibody responses

A new study reported the neutralization of Omicron by a large panel of sera collected from convalescent early pandemic, Alpha, Beta, Gamma and Delta infected individuals, as well as among vaccinees receiving three doses of the Oxford/AstraZeneca (AZD1222) or the Pfizer BioNtech (BNT16b2) vaccines.

7 Jan 2022

Severe Acute Respiratory News and Research

Engineered small extracellular vesicles for the neutralization of SARS-CoV-2

Bolstering current therapeutic antibody treatments to help fight Omicron infections

SARS-CoV-2 Omicron variant uses endosomal entry pathway and grows in upper respiratory tract cells

Emerging SARS-CoV-2 B.1.619 and B.1.620 variants in South Korea

SARS‑CoV‑2 Omicron variant escapes monoclonal antibodies

Lab engineered human A549 lung cell model conducive for investigating SARS-CoV-2 antivirals

SARS-CoV-2 Omicron a product of offensive evolution with compromised antigenicity

Dual-receptors help widespread dissemination of SARS-CoV-2

Study shows probiotics can reduce symptoms of COVID-19 when taken post-exposure

Booster mRNA vaccination effective in reviving anti-SARS-CoV-2 antibody titers among the elderly

Vaccine breakthrough COVID-19 infections found to be less likely transmitted

Researchers investigate SARS-CoV-2 specific inflammatory response

Exploring neurodevelopmental effects on infants from in-utero exposure to COVID-19

Multisystem inflammatory syndrome in children rare after COVID-19 vaccination in adolescents

Reinfection with SARS-CoV-2 in children

SARS-CoV-2 Omicron variant leads to widespread escape from neutralizing antibody responses

Model suggests feasibility of shorter COVID-19 isolation period with minimal risk

Levels of infectious SARS-CoV-2 in vaccinated and unvaccinated individuals

Epidemic model for estimating relative transmissibility and immune escape of SARS-CoV-2 Omicron variant in South Africa

Broad cross-neutralization antibodies found to be effective against SARS-CoV-2 Omicron variant

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

Latest News