Renal Failure News and Research

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Renal failure or kidney failure is where the kidneys fail to function adequately. Renal failure is divided in acute and chronic forms; either form may be due to a large number of other medical problems.

CHOP presents new findings on pediatric cardiovascular disease at AHA 2012

Physician-researchers from the Cardiac Center at The Children's Hospital of Philadelphia presented new findings on pediatric cardiovascular disease at the American Heart Association's Scientific Sessions 2012 in Los Angeles.

9 Nov 2012

State of glycocalyx barrier indicates vascular risk in dialysis patients

The glycocalyx barrier – a mesh of proteoglycans and associated glycosaminoglycans present on vascular endothelium – is impaired in patients with renal failure, probably contributing to their predisposition to endothelial dysfunction and vascular disease, say researchers.

2 Nov 2012

FDA accepts Sunovion’s two LATUDA sNDAs for review

Sunovion Pharmaceuticals Inc. today announced that the U.S. Food and Drug Administration (FDA) has accepted for review two supplemental New Drug Applications (sNDAs) for the use of LATUDA as 1) monotherapy and 2) adjunctive therapy to lithium or valproate, both to treat adult patients with depressive episodes associated with bipolar I disorder (bipolar depression).

31 Oct 2012

Jefferson researchers to investigate mechanisms involved in nephrogenic systemic fibrosis

Researchers at the Jefferson Institute of Molecular Medicine were awarded almost $384,000 by the National Institutes of Health to investigate the mechanisms involved in the development of a serious and sometimes fatal disease, known as Nephrogenic Systemic Fibrosis, a rare skin disorder linked to Gadolinium-based contrast agents used in magnetic resonance (MRI and MRA) studies.

26 Oct 2012

Study hopes to improve the outlook for native Americans with kidney disease

Americans have a 1 in 10 chance of suffering from kidney disease, according to statistics from the Centers for Disease Control and Prevention. For Native Americans, the risk doubles.

19 Oct 2012

Homeless Intermediate Care Pilot Project helps reduce hospital, ED admissions

A nurse outreach programme to treat people using a homeless shelter in London led to a fall of 77 per cent in hospital admissions from the shelter and a cut of 52 per cent in emergency department attendances.

12 Oct 2012

Chronic kidney disease changes the composition of intestinal bacterial microbes

Chronic kidney disease changes the composition of intestinal bacterial microbes that normally play a crucial role in staving off disease-causing pathogens and maintaining micronutrient balance, according to UC Irvine researchers.

10 Oct 2012

Stenting outcomes worse for elderly women than men

Results from a cohort study published in Cardiology show that elderly women have a higher risk for complications and in-hospital mortality immediately after treatment with either drug-eluting stents or bare metal stents than elderly men.

4 Oct 2012

Antibiotic proved to be Achilles’ heel for some

US clinicians have identified patients at particular risk for Achilles injury while using quinolones.

4 Oct 2012

Prevalence of diabetic complications is race-specific

Diabetes is among the ten leading causes of death in both white and African American patients, but the prevalence of diabetic complications are race-specific, according to a recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM).

4 Oct 2012

ASTRO selects Boston-area resident as 2012 Survivor Circle Award winner

The American Society for Radiation Oncology (ASTRO) has selected Boston-area resident and prostate cancer survivor Emanuel "Manny" Hamelburg as its 2012 Survivor Circle Award winner.

3 Oct 2012

WHO urges health workers to be alert for patients exhibiting symptoms of new SARS-like virus

"The World Health Organization on Wednesday urged health workers around the world to report any patient with acute respiratory infection who may have traveled to Saudi Arabia or Qatar and been exposed to a new SARS-like virus confirmed in two people so far," Reuters reports.

27 Sep 2012

Important data from Pfizer’s lung cancer and RCC portfolios to be presented at ESMO Congress

Pfizer Oncology today announced that important data from its lung cancer and renal cell carcinoma (RCC) portfolios will be presented at the upcoming European Society for Medical Oncology (ESMO) Congress in Vienna, Austria, September 28 - October 2, 2012.

18 Sep 2012

Autologous skin grafts heal chronic foot ulcers

Scientists have successfully treated chronic diabetic foot ulcers using skin grafts grown from individual patient cell samples.

13 Sep 2012

Sorafenib could be effective against multiple myeloma

Research from Karolinska Institutet in Sweden shows that sorafenib, a drug used for advanced cancer of the kidneys and liver, could also be effective against multiple myeloma. The disease is one of the more common forms of blood cancer and is generally incurable.

6 Sep 2012

AMAG receives Swiss marketing authorization for ferumoxytol to treat iron deficiency anemia

AMAG Pharmaceuticals, Inc. today announced that the Swiss Agency for Therapeutic Products (Swissmedic) has granted marketing authorization in Switzerland for ferumoxytol, an intravenous (IV) iron therapy to treat iron deficiency anemia (IDA) in adult patients with chronic kidney disease.

6 Sep 2012

On-the-spot test aids postsurgical coagulopathy management

Point-of-care thromboelastometric and aggregometric testing helps to reduce exposure to allogenic blood products in patients with coagulopathy after cardiac surgery, a randomized trial shows.

5 Sep 2012

EC grants marketing authorization for Pfizer’s INLYTA to treat renal cell carcinoma

Pfizer Inc. announced today that the European Commission (EC) has granted marketing authorization for INLYTA (axitinib) for the treatment of adult patients with advanced renal cell carcinoma (RCC), a type of kidney cancer, after failure of prior treatment with sunitinib or a cytokine.

4 Sep 2012