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Scientists discover complex cell mechanism that becomes an obstacle for radiation effectiveness

Researchers from Massachusetts General Hospital, Harvard Medical School and CIC bioGUNE discover a complex cell mechanism activated by a protein —HOXB9— that becomes an obstacle for radiation effectiveness.

20 Oct 2011

Scientists uncover vast new gene regulatory network linked with cancer

Researchers at Columbia University Medical Center (CUMC) and two other institutions have uncovered a vast new gene regulatory network in mammalian cells that could explain genetic variability in cancer and other diseases.

15 Oct 2011

Welch Allyn's high-performance healthcare solutions to be showcased at Medica 2011

Welch Allyn, a leading global provider of medical diagnostic devices headquartered in Skaneateles Falls, NY, will showcase its newest generation of connected solutions designed to address the needs of busy medical practices next month at the 2011 Medica International Trade Fair and Congress in Dusseldorf, Germany.

10 Oct 2011

Researchers show how nuclear receptors battle each other during fruit fly metamorphosis

Growing up just got more complicated. Thomas Jefferson University biochemistry researchers have shown for the first time that the receptor for a major insect molting hormone doesn't activate and repress genes as once thought. In fact, it only activates genes, and it is out-competed by a heme-binding receptor to repress the same genes during the larval to pupal transition in the fruit fly.

7 Oct 2011

Study shows Sox2 expression in many adult stem cells

Investigators at the Massachusetts General Hospital (MGH) Center for Regenerative Medicine and the Harvard Stem Cell Institute (HSCI) have found that Sox2 - one of the transcription factors used in the conversion of adult stem cells into induced pluripotent stem cells (iPSCs) - is expressed in many adult tissues where it had not been previously observed.

7 Oct 2011

Researchers discover cell differentiation mechanism

Researchers from the Haematopoietic Differentiation and Stem Cell Biology group at the Centre for Genomic Regulation (CRG), have described one of the mechanisms by which a cell (from the skin, for example) can be converted into another which is completely different.

4 Oct 2011

Novel bipartite gene therapy for retinitis pigmentosa

In a paper published in the October 2011 issue of Experimental Biology and Medicine, a team of researchers at Columbia University Medical Center led by Stephen Tsang, MD, Ph.D have achieved temporary functional preservation of photoreceptors in a mouse model for retinitis pigmentosa (RP) using novel bipartite gene therapy.

1 Oct 2011

Researchers develop HTGTS to map translocatome in the genome

Researchers at Children's Hospital Boston and the Immune Disease Institute (IDI) have created a method for mapping "hot spots" in the genome where chromosomes are most likely to break and recombine, knowledge that helps define the rules that govern when and where breaks occur.

30 Sep 2011

Researchers identify set of proteins that affect development of varicose veins

A new discovery published in the October 2011 print issue of The FASEB Journal explains for the first time what kicks off the process that causes varicose veins.

30 Sep 2011

New technique helps identify how RNA molecules control gene expression

A new technique developed by researchers at the Stanford University School of Medicine allows researchers to identify the exact DNA sequences and locations bound by regulatory RNAs. This information is necessary to understand how the recently identified RNA molecules control the expression of neighboring and distant genes.

30 Sep 2011

Plausible way to circumvent drug resistance in breast cancer cells

Breast cancer cells that mutate to resist drug treatment survive by establishing tiny pumps on their surface that reject the drugs as they penetrate the cell membrane - making the cancer insensitive to chemotherapy drugs even after repeated use.

29 Sep 2011

Clinithink, Acusis to improve clinical documentation in ambulatory and acute care settings

Acusis, LLC and Clinithink Ltd. have agreed to collaborate with the initial goal of enhancing the clinical documentation process in ambulatory and acute care settings through the integration of Clinithink's new and transformative technology into the market-leading Acusis solution: AcuSuite.

29 Sep 2011

Scientists identify proteasome phosphatase that appears to regulate removal of damaged proteins

A study by scientists at the University of California, San Diego and UC Irvine has identified an enzyme called a proteasome phosphatase that appears to regulate removal of damaged proteins from a cell. The understanding of how this process works could have important implications for numerous diseases, including cancer and Parkinson's disease.

28 Sep 2011

Asuragen announces data from Signature LTx v2.0 clinical study on leukemia

Asuragen, Inc. announced today that data from a study evaluating its Signature LTx v2.0, a CE-marked IVD test, for the multiplex detection of fusion transcripts associated with ALL, AML and CML leukemia, will be presented at the upcoming Planet XMAP Europe being held September 28 - 29, 2011 in Vienna, Austria.

27 Sep 2011

Breast imaging reports generated with automatic speech recognition more likely to contain errors

Breast imaging reports generated using an automatic speech recognition system are nearly six times more likely to contain major errors than those generated with conventional dictation transcription, a new study in Canada shows.

23 Sep 2011

Researchers can reverse aging process for human adult stem cells

Researchers have shown they can reverse the aging process for human adult stem cells, which are responsible for helping old or damaged tissues regenerate.

21 Sep 2011

Scientists discover crucial connection in skin formation

Skin is the body's armor, protecting us from disease agents, injury, excessive water loss, and cold and heat. Yet mutations in a single gene, the gene for the protein p63, cause numerous diseases and malformations of the uppermost layer of skin - the epidermis - and other tissues. In the epidermis, these range from skin cancers to dysplasias that cause cracking, bleeding, infection, and discoloration.

21 Sep 2011