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A novel method to identify spike stabilizing mutations for COVID-19 vaccine development

Researchers discuss a robust method to identify mutations that improve the expression and stabilize the conformation of the SARS-CoV-2 spike protein.

29 Sep 2022

Poor metabolic health parameters are linked to low breast milk production, research shows

New research from UC shows that poor metabolic health parameters are linked to low breast milk production. The study was published in the journal Breastfeeding Medicine.

29 Sep 2022

CAR T-cell therapy produces impressive results in first clinical trial in patients with multiple myeloma

A therapy made of immune system T cells engineered to target a somewhat enigmatic cell protein called GPRC5D antigen produced impressive results in its first clinical trial in patients with multiple myeloma, researchers at Memorial Sloan Kettering Cancer Center (MSK), Dana-Farber Cancer Institute and Roswell Park Comprehensive Cancer Center report in a new study published today by the New England Journal of Medicine.

29 Sep 2022

Combined oral contraceptive pills do not appear to exacerbate macromastia-related symptoms

Combined oral contraceptives (COCs) containing both estrogen and progestin do not contribute to the development of enlarged breasts (macromastia) – nor do they increase the risk of breast regrowth in adolescents and young women following breast-reduction surgery, reports a study in the October issue of Plastic and Reconstructive Surgery, the official medical journal of the American Society of Plastic Surgeons (ASPS).

29 Sep 2022

Primary vaccinations and boosters effective in reducing COVID-19 severity during Delta and Omicron predominance

In a new study, researchers analyzed COVID-19 vaccination and surveillance data to understand the effect of primary vaccinations, boosters, and prior SARS-CoV-2 infections on severe COVID-19 outcomes and subsequent infections.

29 Sep 2022

What are the differences in transmissibility between novel and emerging SARS-CoV-2 variants?

In a new study, researchers compared the transmissibility of novel and emerging SARS-CoV-2 variants.

29 Sep 2022

How a major COVID-19 outbreak occurred in a naïve and vaccinated population in Taiwan with a limited number of entry events

Researchers explored the SARS-CoV-2 genome using high-throughput genome sequencing to provide novel insights into how the novel SARS-CoV-2 Omicron BA.2.3.7 variant enters and spreads among the otherwise naïve Taiwanese population.

29 Sep 2022

Study examines the incidence of severe COVID-19 in fully vaccinated and boosted high-risk populations

In new research, scientists studied a cohort of patients at the U.S Veterans Health Administration facilities to determine the incidence of severe COVID-19 outcomes among individuals with primary and booster doses of any combination of BNT162b2, mRNA-1273, and Ad26.COV2.S vaccines.

29 Sep 2022

Study suggests B-cell responses to booster vaccines are impeded by recent SARS-CoV-2 infection

Researchers investigated whether the time of booster vaccination relative to SARS-CoV-2 infection is a crucial determinant of the elicited immune response; in particular, the antibody and B-cell responses.

29 Sep 2022

Exploring remdesivir resistance in COVID-19-infected transplant recipients

In a new study, researchers assessed the remdesivir resistance developed in coronavirus disease 2019 (COVID-19)-infected transplant recipients.

29 Sep 2022

Duration of infectiousness, predictors of ongoing individual infectiousness, and diagnostic tests for acute SARS-CoV-2 infection

Researchers explored SARS-CoV-2 variants of concern/interest (VOC/VOI) kinetics and variations among non-hospitalized acute COVID-19 patients.

29 Sep 2022

Smartphone-based assessment of long COVID symptomatology and risk factors

Researchers quantified the features and risk factors of post-acute COVID-19 syndrome or long COVID based on the integration of survey (active) data and passive [mobile health (mHealth) wearable device] data.

29 Sep 2022

Significant humoral immune evasion contributes to the emergence and rapid spread of Arg346-mutated BA.4 and BA.5 sublineages

=Researchers measured the neutralizing titers of plasma samples against the SARS-CoV-2 new variant of concern Omicron's sub-variants BA.4 and BA.5 with arginine (Arg)346 mutations.

29 Sep 2022

Yourgene Health Receives HSA approval for IONA Nx NIPT Workflow in Singapore

COVID-19 cases, hospitalizations, and fatalities prevented by SARS-CoV-2 vaccination within the first 6 months after the vaccine became available

Researchers assessed the effect of SARS-CoV-2 vaccination in the US.

28 Sep 2022

mRNA boosters associated with decreased odds of hospitalization compared with the mRNA vaccine primary series alone

Researchers assessed the chances of COVID-19 hospitalization after three versus two mRNA vaccine doses.

28 Sep 2022

Syndrome News and Research

A novel method to identify spike stabilizing mutations for COVID-19 vaccine development

Poor metabolic health parameters are linked to low breast milk production, research shows

CAR T-cell therapy produces impressive results in first clinical trial in patients with multiple myeloma

Combined oral contraceptive pills do not appear to exacerbate macromastia-related symptoms

Primary vaccinations and boosters effective in reducing COVID-19 severity during Delta and Omicron predominance

What are the differences in transmissibility between novel and emerging SARS-CoV-2 variants?

How a major COVID-19 outbreak occurred in a naïve and vaccinated population in Taiwan with a limited number of entry events

Study examines the incidence of severe COVID-19 in fully vaccinated and boosted high-risk populations

Study suggests B-cell responses to booster vaccines are impeded by recent SARS-CoV-2 infection

Exploring remdesivir resistance in COVID-19-infected transplant recipients

Duration of infectiousness, predictors of ongoing individual infectiousness, and diagnostic tests for acute SARS-CoV-2 infection

Smartphone-based assessment of long COVID symptomatology and risk factors

Significant humoral immune evasion contributes to the emergence and rapid spread of Arg346-mutated BA.4 and BA.5 sublineages

Yourgene Health Receives HSA approval for IONA Nx NIPT Workflow in Singapore

Study aims to understand how SARS-CoV-2 affects the brain long-term

Treatment for neurological diseases often no longer effective enough in the later stages

Vitamin supplements can benefit cystic fibrosis patients, study suggests

What is the role of N-glycans and calnexin-calreticulin chaperones in SARS-CoV-2 spike maturation?

COVID-19 cases, hospitalizations, and fatalities prevented by SARS-CoV-2 vaccination within the first 6 months after the vaccine became available

mRNA boosters associated with decreased odds of hospitalization compared with the mRNA vaccine primary series alone

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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