Renal Failure News and Research

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Renal failure or kidney failure is where the kidneys fail to function adequately. Renal failure is divided in acute and chronic forms; either form may be due to a large number of other medical problems.

Octogenarians have better survival rates following heart valve surgery

Octogenarians need not shy away from heart valve surgery because of their age; however, those sent home following surgery do better than those discharged to care facilities, according to an observational study published in the September 2012 issue of The Annals of Thoracic Surgery.

30 Aug 2012

Personalized antiplatelet treatment leads to better outcomes in patients undergoing PCI

Personalized antiplatelet treatment leads to better outcomes than standard antiplatelet treatment in patients undergoing coronary stent implantation, according to results from the MADONNA study presented at ESC Congress 2012.

28 Aug 2012

Blood clotting treatment algorithms help decrease transfusion requirements in cardiac surgery patients

In patients who undergo cardiac surgery, severe perioperative bleeding and its treatment are often associated with increases in major cardiac and non-cardiac adverse events and greater mortality. A study from the September issue of Anesthesiology determined certain blood clotting treatment algorithms helped decrease blood transfusion requirements in cardiac surgery patients and were associated with improved outcomes and hospital cost-savings.

23 Aug 2012

Tranexamic acid reduces bleeding in off-pump coronary bypass surgery

Patients undergoing off-pump coronary artery bypass grafting who are given a tranexamic acid infusion show a modest reduction in postoperative bleeding and blood transfusion relative to their placebo-treated peers, a clinical trial shows.

15 Aug 2012

Common antibiotics may risk liver injury in elderly

Regulatory warnings should be considered for the antibiotics moxifloxacin and levofloxacin because of a potential risk for liver injuries in the elderly, Canadian researchers suggest.

14 Aug 2012

Combination therapy does not change safety and efficacy relationship of TORISEL for advanced RCC

Pfizer Inc. announced that the Phase 3 INTORACT trial (B1771006), evaluating the combination of bevacizumab plus TORISEL (temsirolimus) compared with bevacizumab plus interferon-alfa-2a (IFN-α-2a) in the first-line treatment of patients with advanced renal cell carcinoma (RCC) across risk groups, did not meet its primary endpoint of superiority in extending progression free survival (PFS) in the study population.

12 Aug 2012

Pendrin a possible new target for diuretic therapy

In patients with fluid overload, inhibition of the chloride-absorbing transporter pendrin and the NaCl co-transporter may provide an effective diuretic regimen without triggering hypokalemia, research suggests.

6 Aug 2012

Prior contralateral amputation predicts outcomes after LEB for critical limb ischemia

Researchers from the Vascular Study Group of New England (VSGNE) report that prior contralateral amputation predicts worse outcomes for lower extremity bypasses (LEB's) performed in the intact limb.

6 Aug 2012

Potential new drug to treat common inherited kidney disease

Scientists at UC Santa Barbara have demonstrated in the laboratory that a new drug is effective in treating a very common kidney disease -- although it will be a few years before it becomes available for clinical testing. The findings resulted from a collaboration between UCSB and a biotech firm based in Indiana. The study is published in this week's Journal of the American Society of Nephrology.

3 Aug 2012

FDA grants accelerated approval for Kyprolis to treat multiple myeloma

Ligand Pharmaceuticals Incorporated today announced that its licensee, Onyx Pharmaceuticals, received accelerated approval from the U.S. Food and Drug Administration (FDA) for Kyprolis (carfilzomib) for Injection, a proteasome inhibitor indicated for the treatment of patients with multiple myeloma who have received at least two prior therapies, including bortezomib and an immunomodulatory agent, and have demonstrated disease progression on or within 60 days of completion of the last therapy.

21 Jul 2012

FDA grants accelerated approval to Onyx's Kyprolis for treatment of multiple myeloma

Onyx Pharmaceuticals, Inc. today announced that the U.S. Food and Drug Administration (FDA) has granted accelerated approval of Kyprolis (carfilzomib) for Injection, a proteasome inhibitor, indicated for the treatment of patients with multiple myeloma who have received at least two prior therapies, including bortezomib and an immunomodulatory agent, and have demonstrated disease progression on or within 60 days of completion of the last therapy.

21 Jul 2012

Robotic surgery shows promise for local control of OSCC

In individuals with low-risk oropharyngeal squamous cell carcinoma, treatment with transoral robotic surgery alone can result in an excellent rate of local disease control for up to 3 years, report researchers.

19 Jul 2012

HAS-BLED: Atrial fibrillation patients undergoing angioplasty can still take anticoagulants

Researchers say that oral anticoagulation could improve the prognosis of atrial fibrillation patients who undergo percutaneous coronary intervention, even if they have a high bleeding risk according to the HAS-BLED score.

19 Jul 2012

Positive preliminary results from Feraheme phase III study on iron deficiency anemia

AMAG Pharmaceuticals, Inc. today reported preliminary results from the second phase III study from its global registrational program for Feraheme (ferumoxytol) in patients with iron deficiency anemia (IDA) regardless of the underlying cause.

19 Jul 2012

Gilead receives FDA approval for Truvada to reduce risk of sexually acquired HIV-1 infection

Gilead Sciences, Inc. today announced that the U.S. Food and Drug Administration (FDA) has approved once-daily oral Truvada (emtricitabine and tenofovir disoproxil fumarate), in combination with safer sex practices, to reduce the risk of sexually acquired HIV-1 infection in adults at high risk.

17 Jul 2012

Peripheral arterial disease predicts mortality in TAVI patients

Patients with severe aortic stenosis who undergo transcatheter aortic valve implantation are at particularly high risk for complications and death if they also have concomitant peripheral arterial disease, study results show.

10 Jul 2012

Bankers Life and Casualty introduces new life and health insurance product

Bankers Life and Casualty Company today announced a new addition to its portfolio of life and health insurance products, Critical Benefit.

10 Jul 2012

Critical Diagnostics showcases Presage ST2 Assay at AAHFN annual meeting

Critical Diagnostics, makers of the Presage ST2 Assay, participated in the annual meeting for the American Association of Heart Failure Nurses in Chicago, considered the premier meeting in heart failure nursing.

3 Jul 2012

FDA approves Baxter's GAMMAGARD LIQUID for multifocal motor neuropathy

Baxter International Inc. today announced that the U.S. Food and Drug Administration (FDA) has approved GAMMAGARD LIQUID 10% [Immune Globulin Infusion (Human)] as a treatment for multifocal motor neuropathy (MMN). This is the first immunoglobulin treatment approved for MMN patients in the United States, and it was approved for use with MMN patients in Europe in 2011.

From Baxter International Inc. 25 Jun 2012

EC grants marketing authorization for AMAG's ferumoxytol to treat IDA

AMAG Pharmaceuticals, Inc. today announced that the European Commission has granted marketing authorization for ferumoxytol, an intravenous (IV) iron therapy to treat iron deficiency anemia (IDA) in adult patients with chronic kidney disease (CKD).

23 Jun 2012

Renal Failure News and Research

Further Reading

Octogenarians have better survival rates following heart valve surgery

Personalized antiplatelet treatment leads to better outcomes in patients undergoing PCI

Blood clotting treatment algorithms help decrease transfusion requirements in cardiac surgery patients

Tranexamic acid reduces bleeding in off-pump coronary bypass surgery

Common antibiotics may risk liver injury in elderly

Combination therapy does not change safety and efficacy relationship of TORISEL for advanced RCC

Pendrin a possible new target for diuretic therapy

Prior contralateral amputation predicts outcomes after LEB for critical limb ischemia

Potential new drug to treat common inherited kidney disease

FDA grants accelerated approval for Kyprolis to treat multiple myeloma

FDA grants accelerated approval to Onyx's Kyprolis for treatment of multiple myeloma

Robotic surgery shows promise for local control of OSCC

HAS-BLED: Atrial fibrillation patients undergoing angioplasty can still take anticoagulants

Positive preliminary results from Feraheme phase III study on iron deficiency anemia

Gilead receives FDA approval for Truvada to reduce risk of sexually acquired HIV-1 infection

Peripheral arterial disease predicts mortality in TAVI patients

Bankers Life and Casualty introduces new life and health insurance product

Critical Diagnostics showcases Presage ST2 Assay at AAHFN annual meeting

FDA approves Baxter's GAMMAGARD LIQUID for multifocal motor neuropathy

EC grants marketing authorization for AMAG's ferumoxytol to treat IDA

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