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New insights into how myasthenia gravis antibodies disrupt muscle function

People who suffer from the autoimmune disease myasthenia gravis experience muscle weakness that can affect any of the muscles we use to blink, smile or even move our body around.

9 Apr 2025

Calibr-Skaggs receives FDA approval to test sCAR-T therapy in patients with autoimmune diseases

Calibr-Skaggs Institute for Innovative Medicines, the drug discovery division of Scripps Research, announced today that the FDA has cleared their investigational new drug (IND) application to study switchable chimeric antigen receptor T cell (sCAR-T) therapy (CLBR001 + SWI019) in patients with autoimmune conditions.

9 Apr 2025

MSC-derived extracellular vesicles show promise in treating high-dose radiation injuries

A new study in the peer-reviewed journal Stem Cells and Development highlights the potential of mesenchymal stem cell (MSC)-derived extracellular vesicles (EVs) as a therapeutic strategy for high-dose radiation injuries by promoting hematopoietic recovery and improving survival.

9 Apr 2025

Heavy drinking linked to increased risk of brain lesions

Heavy drinkers who have eight or more alcoholic drinks per week have an increased risk of brain lesions called hyaline arteriolosclerosis, signs of brain injury that are associated with memory and thinking problems, according to a study published on April 9, 2025, online in Neurology®, the medical journal of the American Academy of Neurology.

9 Apr 2025

Gut microbes and metabolites reveal how lifestyle changes help prevent type 2 diabetes

Researchers identified 502 blood metabolites linked to prediabetes and type 2 diabetes, with 143 tied to the gut microbiome. The study shows how lifestyle interventions like diet and exercise can modify metabolomic profiles to support glucose control.

9 Apr 2025

UCLA study identifies key protein driving kidney scarring

New UCLA research conducted using mouse models and human genetic data has uncovered a critical factor that determines how much scarring occurs following kidney injury, leading scientists to identify a potential precision medicine approach to prevent chronic kidney disease progression.

9 Apr 2025

Tulane researchers develop portable device for rapid TB diagnosis

Tulane University researchers have developed a first-of-its-kind handheld diagnostic device that can deliver rapid, accurate tuberculosis diagnoses in under an hour, according to a study published in Science Translational Medicine.

9 Apr 2025

Genetic fusion drives unexpectedly fast growth in chronic myeloid leukemia

A new study has unveiled when chronic myeloid leukemia, a type of cancer that affects the blood and bone marrow, arises in life and how fast it grows.

9 Apr 2025

New method uses sugar molecules to identify pancreatic cancer subtypes

Van Andel Institute scientists and collaborators have developed a new method for identifying and classifying pancreatic cancer cell subtypes based on sugars found on the outside of cancer cells.

9 Apr 2025

Eating ultra-processed foods may rewire your brain’s hunger and reward circuits

High intake of ultra-processed foods is linked to adverse metabolic health and microstructural brain changes in regions that control appetite and reward. These effects occur both through obesity-related pathways and independently via inflammation and dyslipidemia.

9 Apr 2025

Menstrual cycle may drive inflammation in women with sickle cell disease

A marker linked to inflammation, C-reactive protein, may increase significantly during the follicular phase of the menstrual cycle in female patients with sickle cell disease (SCD), according to emerging research published today in Blood Vessels, Thrombosis & Hemostasis.

9 Apr 2025

Mirvie reveals new advances in the biological understanding of hypertensive disorders of pregnancy

Today, Mirvie announced results of a breakthrough study published in Nature Communications, revealing new advances in the biological understanding of hypertensive disorders of pregnancy (HDP), including preeclampsia - a leading cause of maternal morbidity and mortality as well as preterm birth.

9 Apr 2025

Fish swim bladder hydrogel shows promise in heart repair

Hydrogels, which are soft materials formed by crosslinking polymers, could have a variety of medical applications.

9 Apr 2025

Laser-based infrared molecular fingerprinting detects common cancers

Cancer diagnoses traditionally require invasive or labor-intensive procedures such as tissue biopsies.

9 Apr 2025

Dynamic BH3 profiling offers personalized lung cancer therapies

Eighty-five percent of diagnosed cases of lung cancer are non-small cell lung cancer (NSCLC). In this group, 5% of patients show molecular alterations in the ALK gene involved in cell multiplication.

9 Apr 2025

This bill aims to help firefighters with cancer. Getting it passed is just the beginning.

As firefighters battled the catastrophic blazes in Los Angeles County in January, California's U.S. senators, Adam Schiff and Alex Padilla, signed onto legislation with a simple aim: Provide federal assistance to first responders diagnosed with service-related cancer.

9 Apr 2025

Rural hospitals and patients are disconnected from modern care

Leroy Walker arrived at the county hospital short of breath. Walker, 65 and with chronic high blood pressure, was brought in by one of rural Greene County’s two working ambulances.

9 Apr 2025

What happens if you significantly increase dietary folic acid intake?

Increased dietary folic acid intake may lead to adverse health effects, including inflammation and neurotoxicity, highlighting the need for optimal levels.

9 Apr 2025

Relaxation methods offer temporary relief for high blood pressure

Relaxation techniques may help lower high blood pressure-at least in the short term-but the longer term effects are unclear, finds a pooled data analysis of the existing research published in the open access journal BMJ Medicine.

9 Apr 2025

QRICH1 protein discovery opens new avenues for cancer and autoimmune therapies

In a study of the immune systems of mice, scientists at Johns Hopkins Medicine say they have found a new role for a protein, QRICH1, which could become a target for drugs to dial up or down the activation of T cells to fight cancers and autoimmune diseases.

9 Apr 2025