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New immune map uncovers key pancreatic cancer insights

Researchers determine a complex immune infiltrate pattern based on a newly constructed immune map developed using pancreatic cancer cells.

12 Feb 2025

Mechanical heart valves offer better long-term survival for patients aged 50-70

Patients aged between 50 to 70 years with a mechanical heart valve replacement had better long-term survival compared to those with a biological valve, new research led by the University of Bristol has found.

11 Feb 2025

New guidelines urge caution with ketamine use for mental health treatment

The anesthetic ketamine is being hailed as a breakthrough therapy for people with post-traumatic stress disorder (PTSD), treatment-resistant depression and other mood disorders.

11 Feb 2025

UVA launches trial to test AI-powered device for diabetes management

For people living with Type 1 Diabetes (T1D), keeping blood sugar levels in check is a constant challenge.

11 Feb 2025

Air pollution harms cognition just hours after exposure, study finds

New research shows that inhaling polluted air for just an hour can impair cognitive abilities like attention and emotional recognition within four hours, highlighting the urgent need for cleaner air policies.

11 Feb 2025

Broccoli sprouts may help prediabetes, but only with the right gut bacteria

Broccoli sprout extract (BSE) modestly lowered fasting blood glucose in prediabetes, but its effectiveness depended on gut microbiota, particularly the BT2160 operon.

11 Feb 2025

One shot to lower cholesterol for life? Scientists unlock a groundbreaking gene therapy

Researchers developed an epigenetic editing approach to silence the PCSK9 gene, achieving long-term cholesterol reduction without altering DNA, offering a potential one-time treatment for high cholesterol.

11 Feb 2025

Lung signals trigger blood clot formation in cancer patients

Blood clots form in response to signals from the lungs of cancer patients—not from other organ sites, as previously thought—according to a preclinical study by Weill Cornell Medicine, Memorial Sloan Kettering Cancer Center and University of California San Diego Health. Clots are the second-leading cause of death among cancer patients with advanced disease or aggressive tumors.

11 Feb 2025

New method provides accurate measurement of drug permeability across the blood-brain barrier

For decades, scientists across the globe have investigated methods to accurately measure drug permeability across the blood-brain barrier, a compact layer of cells that protect the brain from potentially dangerous substances and microbes.

11 Feb 2025

Targeted polymersomes boost methotrexate efficacy for aggressive choriocarcinoma treatment

Researchers develop targeted polymersomes loaded with methotrexate for the treatment of gestational choriocarcinoma,

11 Feb 2025

Changes to intermediate filament protein drive aggressive breast cancer growth

Changes to the intermediate filament (IF) protein, vimentin, were found to promote tumor growth by increasing cancer stemness in an oestrogen independent manner.

11 Feb 2025

Novel biomarker for early prevention of Alzheimer’s disease

New serine biomarkers show promise for early Alzheimer's detection, linking tau assemblies to cognitive decline and offering potential for timely intervention.

11 Feb 2025

Severe infections linked to increased risk of heart failure

Findings highlight the importance of infection prevention measures and personalized heart failure care.

11 Feb 2025

NIH clinical trial examines investigational therapy for dengue

A clinical trial supported by the National Institutes of Health (NIH) is testing an experimental treatment designed to help people suffering the effects of dengue, a mosquito-borne viral disease.

11 Feb 2025

Childhood physical activity can prevent tobacco smoking in adolescence

Teenagers may be less likely to initiate tobacco smoking if they engage in moderate-to-vigorous physical activity (MVPA) from childhood, a new study conducted in collaboration between the Universities of Bristol and Exeter in the UK, and the University of Eastern Finland shows.

11 Feb 2025

Daily fruit and vegetable extracts may boost brain power

A study reveals polyphenol-rich nutraceuticals enhance cognitive performance and boost neuroprotective biomarkers, offering a dietary approach to brain health.

11 Feb 2025

Adrenomedullin hormone as key driver of insulin resistance in obesity-linked type 2 diabetes

Researchers investigate the underlying mechanisms of endothelial insulin resistance involved in obesity-associated diabetes.

11 Feb 2025

AI approach reveals possible fusion of rare diseases in COVID-19 origins

Despite extensive research, the origins of COVID-19 remain elusive. In a new study published in the KeAi journal Advances in Biomarker Sciences and Technology (ABST), an AI-driven approach was adopted to examine DNA methylation patterns at 865,859 CpG sites in blood samples from early COVID-19 patients.

10 Feb 2025

Study assesses perceptions and barriers to integrated care training and practice

Integrated care – a coordinated approach that addresses patients' physical, mental and social health needs – has been shown to improve patient outcomes, reduce health care costs and address health disparities.

10 Feb 2025

Your gut bacteria shape your health from childhood to old age, study reveals

Researchers found that gut microbiome composition is strongly linked to metabolic health across different life stages, with greater effects seen in older adults.

10 Feb 2025