Cholesterol News and Research

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Cholesterol is a waxy, fat-like substance made in the liver, and found in the blood and in all cells of the body. Cholesterol is important for good health and is needed for making cell walls, tissues, hormones, vitamin D, and bile acid.

Diet drinks showed no clear weight-loss edge over water after two years

In a two-year randomized trial combining assisted weight management with an unassisted follow-up year, completers maintained average weight losses of 4.8 kg with diet drinks and 3.7 kg with water. Researchers found no significant difference between groups, but fewer than half of the 493 participants completed follow-up.

11 Oct 2026

What people ate at the start of a 20-year study was linked to their heart failure odds

Researchers linked higher baseline diet quality to lower odds of developing heart failure over 20 years among 2,159 Greek adults initially free of cardiovascular disease. Healthy-food consumption showed the most consistent association, but the observational study cannot establish that dietary changes prevent heart failure.

11 Oct 2026

Better blood pressure control could prevent over 518,000 annual deaths worldwide

Effective management of high blood pressure could prevent more than 518,000 annual deaths from cardiovascular disease around the world, according to preliminary research presented at the American Heart Association's Hypertension Scientific Sessions 2026.

11 Oct 2026

Does extra protein protect aging muscle during fasting?

A randomized trial found that alternate-day fasting reduced weight in older men, while added protein and leucine did not prevent lean mass loss.

7 Oct 2026

Statins may lower glaucoma risk and reduce treatment needs

Taking statins is linked to a lower risk of developing glaucoma and a reduced chance of it getting worse, suggest the findings of research published online in the British Journal of Ophthalmology.

6 Oct 2026

Enlicitide offers oral treatment option for patients avoiding cholesterol injections

In 2015, a new class of cholesterol-lowering injectable drugs called PCSK9-inhibitors was approved by the Food and Drug Administration (FDA) as a result of clinical research led by UT Southwestern.

5 Oct 2026

Poor nutrition scores predict mortality risk beyond body weight

In a population-based cohort of 8,398 adults in Leipzig, Germany, poorer nutritional status measured using several laboratory-based scores was associated with a higher risk of all-cause mortality over a median follow-up of about 7.5 years.

5 Oct 2026

Very low carbohydrate diets show potential benefits in children with type 1 diabetes

Very low carbohydrate (VLC) diets may be associated with health benefits in children with type 1 diabetes (T1D) and were not associated with acute diabetes complications, new research being presented at the annual meeting of the European Association for the Study of Diabetes (EASD) in Milan, Italy (Sept 28 – Oct 2) has found.

1 Oct 2026

CBL-514 injection reduces visceral and subcutaneous fat in trials

Details of a new injection that targets fat cells will be released at the annual meeting of the European Association for the Study of Diabetes (EASD) in Milan, Italy (Sept 28 – Oct 2).

1 Oct 2026

Petrelintide produces double-digit weight loss with fewer side effects

New research to be presented at the Annual Meeting of The European Association for the Study of Diabetes (EASD) in Milan, Italy (Sept 28 – Oct 2) and published in The Lancet Diabetes & Endocrinology shows that weekly injections with the new amylin-based obesity drug petrelintide can enable those treated to lose more than 10% of their body weight – generally lower than existing incretin-based (GLP-1 RA) drugs, but also with far fewer side effects.

29 Sep 2026

First EU Screening Week urges citizens to know their numbers

At a dedicated press conference at the EASD Annual Meeting in Milan, organized by the European Diabetes Forum (EUDF), three leading European cardiometabolic scientific associations - the European Society of Cardiology (ESC), the European Association for the Study of Diabetes (EASD) and the European Association for the Study of Obesity (EASO) - joined European Commissioner for Health and Animal Welfare Olivér Várhelyi to welcome the launch of the first-ever EU Screening Week.

29 Sep 2026

University of Liverpool study tracks long-term impact of non-nutritive sweetened soft drinks

Researchers at the University of Liverpool have conducted the longest and most comprehensive randomized controlled trial on non-nutritive sweetened (NNS) soft drinks.

29 Sep 2026

From espresso to filter coffee, brewing may shape what reaches your gut

A focused narrative review traces how caffeine, chlorogenic acids, and coffee fibers move through the gut and interact with microbes. The authors identify plausible links between the microbiome and liver health, but human studies have not shown that microbiome changes cause coffee’s reported metabolic benefits.

28 Sep 2026

Research makes strong case for broader use of GLP1 drugs to protect hearts

New research being presented at the annual meeting of the European Association for the Study of Diabetes (EASD) in Milan, Italy (Sept 28 – Oct 2) makes a case for extending the indication for GLP1- receptor agonists (GLP1-RAs) to millions more people, to protect their heart health.

28 Sep 2026

A survey of 371,000 adults links heart disease to eating whole fruit less often

In a survey analysis of 371,038 US adults, those reporting high blood pressure, high cholesterol, a heart attack, or coronary heart disease ate whole fruit slightly less often than those without the respective conditions. After adjustment, 100% fruit-juice consumption was less frequent among adults with high cholesterol and more frequent among those reporting a heart attack, but the cross-sectional study cannot establish cause and effect.

28 Sep 2026

Semaglutide cuts major heart events, but researchers still cannot fully explain why

In adults with overweight or obesity and established cardiovascular disease but no diabetes, semaglutide reduced major adverse cardiovascular events by 20%, while changes in measured cardiovascular risk factors could not fully explain the benefit with certainty. The findings suggest that additional, as-yet unidentified biological pathways may contribute to semaglutide’s cardiovascular protection.

27 Sep 2026

New study tracks rising heart and kidney risks in people with type 2 diabetes

The risk of developing chronic kidney disease (CKD) or heart failure (HF), or dying, following a type 2 diabetes (T2D) diagnosis increases substantially over time, according to new research being presented at the Annual Meeting of The European Association for the Study of Diabetes (EASD) in Milan, Italy (Sept 28 – Oct 2).

27 Sep 2026

Toxoplasma remodels host cell surfaces to trigger invasion

At first, cholesterol and glycosylation seemed like two separate leads. As the researchers followed them, however, the pathways converged.

25 Sep 2026

Mount Sinai researchers discover how Alzheimer's gene damages blood vessels

Mount Sinai researchers have identified how APOE4, the strongest genetic risk factor for Alzheimer's disease, damages the brain's blood vessels and promotes the buildup of abnormal proteins linked to neurodegenerative disease.

24 Sep 2026

Advances in chemistry and delivery are taking oligonucleotide medicines beyond rare diseases

A review in Cell Reports Medicine examines how advances in oligonucleotide chemistry and delivery have established ASOs and RNA interference therapies as a class of genetic medicines, with 21 oligonucleotides approved at the time of writing. It also identifies extrahepatic delivery, safety, target validation, individualized treatment, and data quality as priorities as the field expands into common diseases and explores AI-assisted development.

24 Sep 2026

Cholesterol News and Research

Further Reading

Diet drinks showed no clear weight-loss edge over water after two years

What people ate at the start of a 20-year study was linked to their heart failure odds

Better blood pressure control could prevent over 518,000 annual deaths worldwide

Does extra protein protect aging muscle during fasting?

Statins may lower glaucoma risk and reduce treatment needs

Enlicitide offers oral treatment option for patients avoiding cholesterol injections

Poor nutrition scores predict mortality risk beyond body weight

Very low carbohydrate diets show potential benefits in children with type 1 diabetes

CBL-514 injection reduces visceral and subcutaneous fat in trials

Petrelintide produces double-digit weight loss with fewer side effects

First EU Screening Week urges citizens to know their numbers

University of Liverpool study tracks long-term impact of non-nutritive sweetened soft drinks

From espresso to filter coffee, brewing may shape what reaches your gut

Research makes strong case for broader use of GLP1 drugs to protect hearts

A survey of 371,000 adults links heart disease to eating whole fruit less often

Semaglutide cuts major heart events, but researchers still cannot fully explain why

New study tracks rising heart and kidney risks in people with type 2 diabetes

Toxoplasma remodels host cell surfaces to trigger invasion

Mount Sinai researchers discover how Alzheimer's gene damages blood vessels

Advances in chemistry and delivery are taking oligonucleotide medicines beyond rare diseases

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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