Renal Failure News and Research

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Renal failure or kidney failure is where the kidneys fail to function adequately. Renal failure is divided in acute and chronic forms; either form may be due to a large number of other medical problems.

Hospitals with higher diagnosis frequency for chronic conditions have lower case-fatality rate

An examination of data for more than 5 million Medicare beneficiaries finds that hospital regions that have a greater frequency of diagnoses have a lower case-fatality rate for chronic conditions such as coronary artery disease and kidney failure, according to a study in the March 16 issue of JAMA.

16 Mar 2011

Researchers discover new gene for Sensenbrenner syndrome

Dutch researchers of the Radboud University Medical Center in Nijmegen found a new gene for Sensenbrenner syndrome (Journal of Medical Genetics, 2011 Mar 4). The mutation adds support to the hypothesis that defects in ciliar transport are the cause of the disease. Project leader Dr. Heleen H. Arts is supported by a Kolff Junior Postdoc Grant of the Dutch Kidney Foundation.

14 Mar 2011

Merck to present VICTRELIS phase III study data against HCV at EASL annual meeting

Merck, known as MSD outside of the United States and Canada, announced that several new data analyses from Phase III studies of VICTRELIS, its investigational oral hepatitis C protease inhibitor, will be presented at The International Liver CongressTM / 46th European Association for the Study of the Liver annual meeting.

9 Mar 2011

Takeda receives FDA approval for EDARBI to treat hypertension in adults

Takeda Pharmaceutical Company Limited and its wholly-owned subsidiary, Takeda Pharmaceuticals North America, Inc., today announced that the U.S. Food and Drug Administration approved EDARBI for the treatment of hypertension, or high blood pressure, in adults.

27 Feb 2011

Ballerinas need to know dangers of excessive weight loss and overexercise

With actress Natalie Portman in Oscar contention, the movie "Black Swan" has taken center stage. So have concerns surrounding the dramatic weight loss Portman underwent for the role. Her depiction of a dangerously thin ballerina sheds light on a potential downside of this art form.

25 Feb 2011

Study: More effective therapies needed for diabetes patients with ESRD

Despite significant advances in kidney care over the past 20 years, efforts to improve therapy for type 1 diabetes patients with kidney dysfunction remain unsuccessful, according to a study appearing in an upcoming issue of the Journal of the American Society Nephrology. The results suggest that more effective therapies are needed for these patients.

24 Feb 2011

New research: Significant number of HCV patients in the U.S. does not have health insurance coverage

New research has determined that patients in the U.S. with hepatitis C virus are twice as likely to not have health insurance coverage compared with those without the disease.

24 Feb 2011

Lack of health insurance limits Hepatitis C patients' access to latest antiviral therapy

New research has determined that patients in the U.S. with hepatitis C virus (HCV) are twice as likely to not have health insurance coverage compared with those without the disease. In fact researchers found only a third of HCV infected Americans have access to antiviral therapy; the remaining are either uninsured or not candidates for therapy due to treatment contraindications. Details of this study are published in the March issue of Hepatology, a peer-reviewed journal of the American Association for the Study of Liver Diseases (AASLD).

24 Feb 2011

Raptor reopens enrollment in DR Cysteamine Phase 3 trial to treat patients with nephropathic cystinosis

Raptor Pharmaceutical Corp., today announced it has reopened enrollment in its Phase 3 clinical trial of its proprietary delayed-release oral formulation of cysteamine bitartrate in patients with nephropathic cystinosis.

15 Feb 2011

Dabigatran drug helps prevent blood clots in patients with atrial fibrillation

The newly approved drug dabigatran is an alternative to warfarin to help prevent dangerous blood clots in patients with atrial fibrillation, according to updated guidelines from the American College of Cardiology, American Heart Association and the Heart Rhythm Society.

15 Feb 2011

State court jury rules in favor of Merck in FOSAMAX trial

Merck & Co., Inc. today said a state court jury in New Jersey found in its favor in the Rosenberg v. Merck case, rejecting the claims of a woman who blamed her dental and jaw related problems on her FOSAMAX use.

15 Feb 2011

AHRQ: $25.3 billion spent for kidney disease treatment every year

Overall, an average of 3.7 million adults in the United States were treated for kidney disease each year between 2003 and 2007, according to the latest News and Numbers from the Agency for Healthcare Research and Quality. Kidney disease can lead to renal failure and may be caused by diabetes, high blood pressure and heart disease.

11 Feb 2011

Topical cream used to treat skin diseases activates two distinct neuronal signaling pathways

Scratching deep beneath the surface, a team of researchers from the University of California, San Diego School of Medicine and three South Korean institutions have identified two distinct neuronal signaling pathways activated by a topical cream used to treat a variety of skin diseases. One pathway produces the therapeutic benefit; the other induces severe itching as a side effect.

9 Feb 2011

Merck announces publication of GARDASIL pivotal Phase III study data in NEJM

Merck announced today that data from the pivotal Phase III study with GARDASIL in males were published in the February 3 issue of the New England Journal of Medicine.

3 Feb 2011

Zebrafish research findings may provide potential to improve kidney function in humans

It is estimated that up to 10 percent of the U.S. population may have some form of renal disease, with 450,000 patients with end stage renal disease requiring hemodialysis. Researchers at Brigham and Women's Hospital, Massachusetts General Hospital and the University of Pittsburgh have identified a cell in zebrafish that can be transplanted from one fish to another to regenerate nephrons, providing the potential to improve kidney function.

2 Feb 2011

Baxter launches OLIMEL emulsion for parenteral nutrition

Baxter International today announced the launch of OLIMEL emulsion for infusion in Canada at the American Society of Parenteral and Enteral Nutrition's Clinical Nutrition Week.

From Baxter International Inc. 31 Jan 2011

Disparities in limb salvage procedures may be driven by SES, access to high-volume hospitals

Researchers from Brigham and Women's Hospital at Harvard Medical School in Boston, MA have published a study in the February Journal of Vascular Surgery stating that disparities in limb salvage procedures may be driven by socioeconomic status and access to high-volume hospitals.

29 Jan 2011

Raptor completes enrollment in DR Cysteamine Phase 3 clinical trial in cystinosis

Raptor Pharmaceutical Corp., today announced it has completed enrollment in its Phase 3 clinical trial of its proprietary delayed-release oral formulation of cysteamine bitartrate ("DR Cysteamine") in patients with nephropathic cystinosis ("cystinosis").

24 Jan 2011

Study shows new cardio-pulmonary resuscitation technique increases long-term survival of patients

A study led by Dr. Tom P. Aufderheide, professor of emergency medicine at The Medical College of Wisconsin, shows an alternative method of cardio-pulmonary resuscitation increases long-term survival of patients.

19 Jan 2011

BioCryst reports positive results from peramivir Phase 3 study in influenza

BioCryst Pharmaceuticals, Inc. today announced top-line results from one of its two Phase 3 studies of intravenous (i.v.) peramivir for the treatment of patients hospitalized with influenza, and provided an update regarding its peramivir program.

13 Jan 2011

Renal Failure News and Research

Further Reading

Hospitals with higher diagnosis frequency for chronic conditions have lower case-fatality rate

Researchers discover new gene for Sensenbrenner syndrome

Merck to present VICTRELIS phase III study data against HCV at EASL annual meeting

Takeda receives FDA approval for EDARBI to treat hypertension in adults

Ballerinas need to know dangers of excessive weight loss and overexercise

Study: More effective therapies needed for diabetes patients with ESRD

New research: Significant number of HCV patients in the U.S. does not have health insurance coverage

Lack of health insurance limits Hepatitis C patients' access to latest antiviral therapy

Raptor reopens enrollment in DR Cysteamine Phase 3 trial to treat patients with nephropathic cystinosis

Dabigatran drug helps prevent blood clots in patients with atrial fibrillation

State court jury rules in favor of Merck in FOSAMAX trial

AHRQ: $25.3 billion spent for kidney disease treatment every year

Topical cream used to treat skin diseases activates two distinct neuronal signaling pathways

Merck announces publication of GARDASIL pivotal Phase III study data in NEJM

Zebrafish research findings may provide potential to improve kidney function in humans

Baxter launches OLIMEL emulsion for parenteral nutrition

Disparities in limb salvage procedures may be driven by SES, access to high-volume hospitals

Raptor completes enrollment in DR Cysteamine Phase 3 clinical trial in cystinosis

Study shows new cardio-pulmonary resuscitation technique increases long-term survival of patients

BioCryst reports positive results from peramivir Phase 3 study in influenza

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