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UCI researchers discover gene critical for muscle repair

University of California, Irvine researchers have identified a gene expressed during regeneration that is critical for muscle repair.

12 Nov 2023

Australian study shows combined genomic screening for major hereditary diseases is cost-effective and health-saving

In an Australian study published in EClinicalMedicine, researchers evaluated the impact of a combined genomic screening program for hereditary breast and ovarian cancer, Lynch syndrome, and familial hypercholesterolemia in young adults. The program proved to be cost-effective, reducing healthcare costs and averting numerous health events, while emphasizing the need for further optimization and equitable access within public healthcare systems.

12 Nov 2023

New calculator estimates a person’s cardiovascular disease risk over the next 30 years

A new calculator estimates a person's risk for cardiovascular disease (CVD) over the next 30 years by combining measures of cardiovascular, kidney and metabolic health for the first time, according to a new American Heart Association Scientific Statement published today in the Association's flagship journal Circulation.

10 Nov 2023

CDC publishes updated and expanded recommendations for clinicians providing pain care

Pain affects the lives of millions of Americans every day and improving pain care and the lives of patients with pain is a public health imperative.

10 Nov 2023

Brazzein and monellin: Safe alternatives to sugar, new research confirms

Toxicity assessments of monellin and brazzein.

10 Nov 2023

New insights into migraine etiology: the role of hepatocyte growth factor

The causal links between pro-inflammatory cytokine expression and migraine.

10 Nov 2023

Associations between screen time, exercise habits, and the onset of dementia, Parkinson's disease, and depression

Researchers explore the prospective link between screen time and the risk of developing dementia, Parkinson's disease, and depression.

10 Nov 2023

Is obesity an independent risk factor for cardiovascular disease?

Researchers explore how obesity contributes to cardiovascular disease by investigating this association in low-risk people.

10 Nov 2023

Preclinical discovery could point the way toward better treatments for type 2 diabetes

A drug currently in clinical trials as a cancer therapy can also stimulate pancreatic beta cells to secrete insulin, revealing a previously unknown mechanism for insulin regulation in type 2 diabetes, according to a new study by Weill Cornell Medicine investigators.

9 Nov 2023

C-Path releases new publication on transforming drug development for neurological disorders

Critical Path Institute (C-Path) is pleased to announce the release of a new peer-reviewed publication, titled "Transforming Drug Development for Neurological Disorders: Proceedings from a Multi-disease Area Workshop," now published in Neurotherapeutics, The Journal of the American Society for Experimental Neurotherapeutics.

9 Nov 2023

Laser hair removal reduces the risk of recurrence in patients with pilonidal disease

Laser epilation, commonly known as laser hair removal, reduced the risk of recurrence in patients with pilonidal disease, an inflammatory, painful, and sometimes chronic or recurring condition, according to research conducted by Peter C. Minneci, M.D., Chair of Surgery at Nemours Children's Health, Delaware Valley, and published in JAMA Surgery.

9 Nov 2023

New device could keep implantable "living pharmacy" cells alive for months

In 2021, a Northwestern University-led research team received a Defense Advanced Research Projects Agency (DARPA) contract worth up to $33 million to develop an implantable "living pharmacy" to control the human body's sleep/wake cycles.

9 Nov 2023

Individuals with severe mental illness are at higher risk of experiencing physical multimorbidity

A new study published in BMJ Mental Health has found that individuals with severe mental illness are almost twice as likely to report physical multimorbidity, emphasizing the critical importance of addressing the intersection between mental and physical health.

9 Nov 2023

Charting the future of IBD treatment: From immune modulators to microRNA therapies

In a recent study published in the journal eGastroenterology, researchers delved into the latest therapeutic strategies for managing inflammatory bowel disease (IBD), including ulcerative colitis and Crohn's disease. The paper discusses emerging treatments ranging from immune-modulating drugs and biologics to novel approaches like microRNA upregulators and stem cell therapies, highlighting the need for precision medicine in IBD care.

8 Nov 2023

Cannabis and derivatives show promise in reducing weight and waist circumference, with nuanced effects on body fat

The study in the International Journal of Obesity reports that cannabis and its derivatives may influence weight and waist circumference, with different effects on body fat, suggesting potential as a therapeutic aid in obesity management.

8 Nov 2023

Live shingles vaccine highly effective in the first year after vaccination and then wanes substantially

The effectiveness of live zoster (shingles) vaccine is highest in the first year after vaccination and then wanes substantially.

8 Nov 2023

Study unravels molecular basis of chronic pain transition

Researchers from the Center for Translational Immunology at University Medical Center Utrecht (the Netherlands) have identified that a transient inflammatory pain causes mitochondrial and redox changes in sensory neurons that persist beyond pain resolution.

8 Nov 2023

Human tissue model reveals diversity of bacterial strategies for urinary tract infections

The research, published today in Science Advances, is the first to use a sophisticated human tissue model to explore the interaction between host and pathogen for six common species that cause urinary tract infections.

8 Nov 2023

New prodrug approach enhances drug delivery to brain cells

A new study from the University of Eastern Finland shows that the delivery of drugs into the brain, and especially into glial cells, can be enhanced with prodrugs that temporarily incorporate thyroxine or a thyroxine-like molecule.

8 Nov 2023

Salivary gland abnormalities in primary Sjögren's become more severe over time, study shows

New research at ACR Convergence 2023, the American College of Rheumatology's (ACR) annual meeting, shows that ultrasound-detected salivary gland abnormalities in primary Sjögren's become more severe over time and that the slow-to-progress disease likely starts long before it is first detected.

7 Nov 2023

Chronic News and Research

UCI researchers discover gene critical for muscle repair

Australian study shows combined genomic screening for major hereditary diseases is cost-effective and health-saving

New calculator estimates a person’s cardiovascular disease risk over the next 30 years

CDC publishes updated and expanded recommendations for clinicians providing pain care

Brazzein and monellin: Safe alternatives to sugar, new research confirms

New insights into migraine etiology: the role of hepatocyte growth factor

Associations between screen time, exercise habits, and the onset of dementia, Parkinson's disease, and depression

Is obesity an independent risk factor for cardiovascular disease?

Preclinical discovery could point the way toward better treatments for type 2 diabetes

C-Path releases new publication on transforming drug development for neurological disorders

Laser hair removal reduces the risk of recurrence in patients with pilonidal disease

New device could keep implantable "living pharmacy" cells alive for months

Individuals with severe mental illness are at higher risk of experiencing physical multimorbidity

Charting the future of IBD treatment: From immune modulators to microRNA therapies

Cannabis and derivatives show promise in reducing weight and waist circumference, with nuanced effects on body fat

Live shingles vaccine highly effective in the first year after vaccination and then wanes substantially

Study unravels molecular basis of chronic pain transition

Human tissue model reveals diversity of bacterial strategies for urinary tract infections

New prodrug approach enhances drug delivery to brain cells

Salivary gland abnormalities in primary Sjögren's become more severe over time, study shows

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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