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OCT-guided PCI does not reduce target vessel failure in complex patients, but improves safety

Optical coherence tomography (OCT)-guided percutaneous coronary intervention (PCI) leads to a larger minimum stent area but does not reduce the two-year rate of target vessel failure compared with angiography-guided PCI, according to late breaking research presented in a Hot Line session today at ESC Congress 2023.

28 Aug 2023

Smartphone-based imaging reveals a breakthrough in identifying infected wounds

A recent study in "Frontiers in Medicine" evaluates the use of hyperspectral imaging (HSI) through a smartphone-based device to differentiate between infected and non-infected wounds. The study found that this portable approach offered 74% accuracy in wound assessment, including 100% sensitivity and 91% specificity in detecting infected wounds.

28 Aug 2023

Eating your way out of pain: How your gut microbiota and diet can help manage chronic discomfort

A recent study in the Nutrients journal employs bibliometrics to explore how nutrition impacts the relationship between gut microbiota and chronic pain. The research highlights the potential of probiotics and prebiotics in managing pain conditions and underscores the need for further studies to understand the interplay between diet, gut health, and chronic pain.

28 Aug 2023

Unlocking ACE2: The enzyme that links COVID-19, heart disease, and diabetes

A recent study in the Journal of Biomedical Science examines the critical role of ACE2, an enzyme involved in blood volume and electrolyte balance, in chronic diseases like cardiovascular conditions, diabetes, and COVID-19. The research suggests that ACE2 could serve as both a disease severity biomarker and a therapeutic target.

28 Aug 2023

How diet and exercise may rewrite the Alzheimer's script at a molecular level

Researchers explore how lifestyle changes like diet and physical activity can influence microRNA expression in Alzheimer's patients, potentially offering new therapeutic avenues. The study fills a research gap in understanding how such lifestyle modifications could affect molecular mechanisms implicated in Alzheimer’s disease.

28 Aug 2023

Pulsed field ablation safe, effective for the treatment of paroxysmal atrial fibrillation

Pulsed field ablation (PFA) is as effective and safe as conventional thermal ablation for the treatment of paroxysmal atrial fibrillation (AF), according to late breaking research presented in a Hot Line session today at ESC Congress 2023.

28 Aug 2023

Intravascular imaging-guided PCI associated with lower rate of target lesion failure

Intravascular imaging-guided percutaneous coronary intervention (PCI) is associated with a lower rate of target lesion failure compared with angiography-guided PCI, according to late breaking research presented in a Hot Line session today at ESC Congress 2023.

28 Aug 2023

Neighborhoods with higher opportunity or lower vulnerability linked to lower risk of pediatric asthma

Residence in neighborhoods with higher opportunity or lower vulnerability in early life may be associated with a decreased risk of pediatric asthma, according to a new study led by researchers at the Harvard Pilgrim Health Care Institute.

28 Aug 2023

Study shows benefit of traditional Chinese medicine for heart failure

The traditional Chinese medicine qiliqiangxin reduces hospitalization for heart failure and cardiovascular death in patients with heart failure and a reduced ejection fraction (HFrEF), according to late breaking research presented in a Hot Line session today at ESC Congress 2023.

28 Aug 2023

Research links hypertensive disorders of pregnancy with dementia

Hypertensive disorders of pregnancy (HDP) — conditions of high blood pressure including chronic/gestational hypertension and preeclampsia — have been strongly linked to heart disease in later life, but, before today, little research has connected these disorders with cognition.

28 Aug 2023

The potential of gut-microbiota-targeted reprogramming interventions designed to prevent the onset and progression of cardiovascular diseases

Researchers discuss the potential of probiotic- and prebiotic-based interventions for managing cardiovascular diseases.

28 Aug 2023

More cities address ‘shade deserts’ as extreme heat triggers health issues

If it weren't for the traffic along South MacDill Avenue, Javonne Mansfield swears you could hear the sizzle of a frying pan.

28 Aug 2023

Adolescence stress exposure impacts rodent brain development and behavior

Adolescence stress exposure in rodents can lead to reduced hippocampal cell proliferation, neuroplasticity, and cognitive impairments, as well as increased depressive-like behaviors. These effects may persist into adulthood but with variable impact.

27 Aug 2023

New report on the impacts of Michigan’s Medicaid expansion shows positive effects and opportunities for improvement

At a pivotal time for Medicaid health coverage for Americans with low incomes, a report on the impacts of Michigan's Medicaid expansion shows very positive effects, as well as opportunities for continued improvements.

25 Aug 2023

UofL researchers receive $11.7 million to study microorganisms throughout the body

University of Louisville researchers have received $11.7 million to study microorganisms throughout the body, including the mouth. What they find could lead to better understanding and treatment of a range of chronic conditions.

25 Aug 2023

Water quality may play a role in NTM pulmonary infections in people with cystic fibrosis

High levels of some minerals and metals in environmental water supplies may increase the risk of nontuberculous mycobacteria (NTM) pulmonary infections in people with cystic fibrosis, according to a new study from the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health.

25 Aug 2023

Two new projects aim to improve health care access for underserved populations

Nansi Boghossian and Melissa Nolan, both associate professors in the Arnold School's Department of Epidemiology and Biostatistics, have been awarded more than $600K each from The Duke Endowment to lead projects that improve access to health care for underserved populations.

25 Aug 2023

Focused update of ESC Heart Failure Guidelines integrates latest evidence-based treatments

A focused update of the European Society of Cardiology (ESC) Heart Failure Guidelines is published online today in European Heart Journal following the results of major new trials that should change the management of patients with heart failure.

25 Aug 2023

Women with endometriosis have more contact with healthcare providers in the years prior to diagnosis

Beginning as far back as ten years before even being diagnosed, women with endometriosis utilise the healthcare system more than women without this chronic illness.

25 Aug 2023

Colchicine does not reduce perioperative AF or MINS in major non-cardiac thoracic surgery

Colchicine does not significantly reduce perioperative atrial fibrillation (AF) or myocardial injury after non-cardiac surgery (MINS) in patients undergoing major non-cardiac thoracic surgery, according to late breaking research presented in a Hot Line session today at ESC Congress 2023.

25 Aug 2023

Chronic News and Research

OCT-guided PCI does not reduce target vessel failure in complex patients, but improves safety

Smartphone-based imaging reveals a breakthrough in identifying infected wounds

Eating your way out of pain: How your gut microbiota and diet can help manage chronic discomfort

Unlocking ACE2: The enzyme that links COVID-19, heart disease, and diabetes

How diet and exercise may rewrite the Alzheimer's script at a molecular level

Pulsed field ablation safe, effective for the treatment of paroxysmal atrial fibrillation

Intravascular imaging-guided PCI associated with lower rate of target lesion failure

Neighborhoods with higher opportunity or lower vulnerability linked to lower risk of pediatric asthma

Study shows benefit of traditional Chinese medicine for heart failure

Research links hypertensive disorders of pregnancy with dementia

The potential of gut-microbiota-targeted reprogramming interventions designed to prevent the onset and progression of cardiovascular diseases

More cities address ‘shade deserts’ as extreme heat triggers health issues

Adolescence stress exposure impacts rodent brain development and behavior

New report on the impacts of Michigan’s Medicaid expansion shows positive effects and opportunities for improvement

UofL researchers receive $11.7 million to study microorganisms throughout the body

Water quality may play a role in NTM pulmonary infections in people with cystic fibrosis

Two new projects aim to improve health care access for underserved populations

Focused update of ESC Heart Failure Guidelines integrates latest evidence-based treatments

Women with endometriosis have more contact with healthcare providers in the years prior to diagnosis

Colchicine does not reduce perioperative AF or MINS in major non-cardiac thoracic surgery

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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