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European Commission approves new indication for ORENCIA in combination with MTX for RA

Bristol-Myers Squibb Company has today announced that on 1 July 2010 the European Commission approved a new indication for ORENCIA® (abatacept), in combination with methotrexate (MTX), for the treatment of moderate to severe active rheumatoid arthritis (RA) in adult patients who have responded inadequately to previous therapy with one or more disease-modifying anti-rheumatic drugs (DMARDs) including MTX or a TNF-alpha inhibitor.

7 Jul 2010

Consumer groups: Force insurers to provide more details justifying price increases

Kaiser Health News staff writer Julie Appleby reports on the continuing evolution of the new health overhaul's implementation rules: "Consumer advocates this week pushed for tough rules on how much information insurers must provide to justify premium increases, a step required by the new health overhaul law" (Appleby, 7/6).

7 Jul 2010

Study finds structural similarities in neocortices of humans and chickens

For more than a century, neuroscientists believed that the brains of humans and other mammals differed from the brains of other animals, such as birds (and so were presumably better). This belief was based, in part, upon the readily evident physical structure of the neocortex, the region of the brain responsible for complex cognitive behaviors.

3 Jul 2010

Karolinska Institutet researchers contribute at ESOF 2010

Researchers and staff from Karolinska Institutet are contributing to Europe's largest cross-disciplinary gathering place with news of everything from neuroscience to bioentrepreneurship. Carl Johan Sundberg, university lecturer and associate professor at Karolinska Institutet, is the founder and initiator of ESOF.

3 Jul 2010

Scientists examine how people and macaque monkeys recognize faces

We meet a multitude of people on a daily basis: the nice waitress in the coffee shop around the corner, the bus driver or the colleagues at the office. Without the ability to recognize faces at first glance we would not be able to distinguish between people. Monkeys also possess the remarkable ability to differentiate faces of group members and to extract the relevant information about the individual directly from the face.

2 Jul 2010

New MRI technology may revolutionize diagnosis of medical conditions

The development of a new magnetic resonance imaging technology that could revolutionise the way medical conditions are diagnosed and treated is to take a major step forward as a £7m research centre is established at the University of York.

2 Jul 2010

Ronin, Hcf-1 bind together to control gene program that stimulates growth of stem cells

Ronin, crucial to the self-renewal of embryonic stem cells, and a co-regulator called Hcf-1, binds to a small strand of DNA called a hyperconserved enhancer element to control a gene "program" that stimulates growth of the stem cells and may even play a role in cancer, said a group of researchers led by Baylor College of Medicine in a current report in the journal Genes and Development.

1 Jul 2010

Study implicates cytokine molecule IL-17 in low back pain associated with herniated discs

An immune cell known to cause chronic inflammation in autoimmune disorders has been identified as a possible culprit in low back pain associated with herniated discs, according to doctors at Duke University Medical Center.

29 Jun 2010

Chemotherapy resistant ovarian tumour cells "re-grow" cancer

Cancer Research UK scientists have discovered certain ovarian tumour cells that are resistant to chemotherapy can survive a first round of treatment and go on to "re-grow" the cancer. This could help explain why the disease can be difficult to treat, according to new research published in Oncogene today (Monday).

28 Jun 2010

Researchers identify novel protein complex that regulates genes in fruit flies and mammals

Researchers from the European Molecular Biology Laboratory in Heidelberg, Germany, and the Max-Planck Institute of Immunobiology Freiburg have identified a novel protein complex that regulates around 4000 genes in the fruit fly Drosophila and likely plays an important role in mammals, too. Published today in Molecular Cell, their findings explain how another regulatory protein can lead a double life.

28 Jun 2010

NKI awarded Phase II SBIR grant to develop new ophthalmic screening device for diabetic retinopathy

Neuro Kinetics, Inc., manufacturers of noninvasive medical diagnostic equipment used worldwide to test for vestibular and neurological conditions, said today that it has been awarded a Phase II Small Business Innovation Research grant to further the company's development of a new ophthalmic screening device and testing protocols for the detection and diagnosis of diabetic retinopathy.

25 Jun 2010

Unisyn Medical Technologies launches probe Conversion program

Unisyn Medical Technologies, Inc., a leading provider of diagnostic ultrasound transducer repair, today announced the launch of its probe Conversion™ program. Radically departing from the traditional model of ultrasound probe repair, Unisyn's Conversion™ provides customers with low fixed-pricing, zero day repair cycle-times, and premium quality probes backed by an industry leading 6-month warranty. In simple terms, Conversion™ offers customers high quality replacement probes at the repair price.

24 Jun 2010

New book provides comprehensive review of the functions of p53 family

The p53 tumor suppressor gene, the "guardian of the genome," protects cells against genotoxic stress but is mutated in many cancers. It encodes one of a family of proteins that regulate cell proliferation, differentiation, senescence, and cell death. Mutations in p53 allow cells to escape normal growth controls and thereby contribute to tumor malignancy.

24 Jun 2010

nContact reports results of physician-initiated Convergent Procedure study of AF

nContact Surgical, Inc. reports with interest today the results of a physician-initiated study of the Convergent Procedure that, for the first time, measured the progress of persistent atrial fibrillation (AF) patients at one-year and six-month intervals. Results of the study, which were presented at the 2010 International Society of Minimally Invasive Cardiac Surgeons meeting in Berlin, Germany, indicated that after one year 80% of patients were in sinus rhythm and off anti-arrhythmic medication as a result of the closed chest, multi-disciplinary AF procedure.

24 Jun 2010

Modern humans can achieve relatively high bite forces using less-powerful jaw muscles: Study

The robust jaws and formidable teeth of some of our ancestors and ape cousins may suggest that humans are wimps when it comes to producing a powerful bite: but a new study has found the opposite is true, with major implications for our understanding of diet in ancestral humans.

23 Jun 2010

EUCODIS Bioscience launches high-performance beta-lactamase

EUCODIS Bioscience, a developer and manufacturer of customized enzymes today announced that it has launched a high-performance beta-lactamase designed to inactivate a broad range of beta-lactam antibiotics. EUCODIS Bioscience is marketing the product under the LacBuster(TM) brand.

23 Jun 2010

Ensemble Discovery announces name change to Ensemble Therapeutics Corporation

Ensemble Discovery today announced that it will begin operating as Ensemble Therapeutics Corporation to reflect the Company's progress and emerging pipeline by applying its macrocycle drug platform to develop novel therapeutics. The new name, Ensemble Therapeutics, conveys the company's leadership and advancement in developing novel macrocycle drug compounds that are small molecules with expanded therapeutic properties of large molecule biological drugs.

22 Jun 2010

International team obtains genome sequence of human body louse

An international team has obtained the genome sequence of the human body louse (Pediculus humanus humanus), a parasite that feeds on the blood of its host and a vector of pathogens that cause diseases such as epidemic typhus, relapsing fever and trench fever.

22 Jun 2010

New study that describes sequencing and analysis of body louse genome published

A global research team led by scientists from the J. Craig Venter Institute today published a new study in the Proceedings of the National Academy of Sciences describing the sequencing and analysis of the body louse genome. Lead author, Ewen Kirkness, Ph.D., JCVI, directed the sequencing and gene-finding efforts in the project. Detailed analysis of the genome was then conducted by a large international group of 71 scientists, coordinated by Barry Pittendrigh, University of Illinois, and Professor Evgeny Zdobnov, University of Geneva Medical School.

22 Jun 2010

Gardner Family Health Network to deploy NextGen Ambulatory EHR, Practice Management, QSI Dental System

NextGen Healthcare Information Systems, Inc., a wholly owned subsidiary of Quality Systems, Inc. and a leading provider of healthcare information systems and connectivity solutions, today announced an agreement with Gardner Family Health Network to deploy NextGen® Ambulatory EHR and NextGen® Practice Management, as well as the QSI Dental System. Gardner is the 42nd health center in California to partner with NextGen Healthcare.

22 Jun 2010

Evolution News and Research

European Commission approves new indication for ORENCIA in combination with MTX for RA

Consumer groups: Force insurers to provide more details justifying price increases

Study finds structural similarities in neocortices of humans and chickens

Karolinska Institutet researchers contribute at ESOF 2010

Scientists examine how people and macaque monkeys recognize faces

New MRI technology may revolutionize diagnosis of medical conditions

Ronin, Hcf-1 bind together to control gene program that stimulates growth of stem cells

Study implicates cytokine molecule IL-17 in low back pain associated with herniated discs

Chemotherapy resistant ovarian tumour cells "re-grow" cancer

Researchers identify novel protein complex that regulates genes in fruit flies and mammals

NKI awarded Phase II SBIR grant to develop new ophthalmic screening device for diabetic retinopathy

Unisyn Medical Technologies launches probe Conversion program

New book provides comprehensive review of the functions of p53 family

nContact reports results of physician-initiated Convergent Procedure study of AF

Modern humans can achieve relatively high bite forces using less-powerful jaw muscles: Study

EUCODIS Bioscience launches high-performance beta-lactamase

Ensemble Discovery announces name change to Ensemble Therapeutics Corporation

International team obtains genome sequence of human body louse

New study that describes sequencing and analysis of body louse genome published

Gardner Family Health Network to deploy NextGen Ambulatory EHR, Practice Management, QSI Dental System

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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