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The genetics of neurogenic inflammation in rosacea

Researchers identify rare genetic variants in families with rosacea.

11 Jul 2023

Acute kidney injury does not predict worsening kidney function trajectory in CKD patients

A study of hospitalized persons with chronic kidney disease (CKD) fournd that acute kidney injury (AKI) did not predict worsening of kidney function trajectory once difference in pre-hospitalization characteristically were fully accounted for.

10 Jul 2023

Few studies highlight the effects of lifestyle interventions on postpartum blood pressure

Hypertensive disorders of pregnancy such as preeclampsia and gestational hypertension occur in up to 10% of pregnancies and are associated with a three-fold increased risk of chronic hypertension and up to two-fold increased risk of cardiovascular disease when compared with healthy pregnancies.

10 Jul 2023

Two anti-inflammatory drugs reduce deaths in severe COVID-19 patients

Two anti-inflammatory drugs, abatacept and infliximab, reduced deaths among patients hospitalized with severe COVID-19, according to a national study led by Washington University School of Medicine in St. Louis. William G. Powderly, MD, (right) who led the large clinical trial, discusses patient conditions with Maanasi Samant, MD, in the intensive care unit at Barnes-Jewish Hospital, one of the major trial sites, during the COVID-19 pandemic.

10 Jul 2023

American Heart Association calls for shift to value-based payment system in cardiovascular care

The American Heart Association, a global force for longer, healthier lives for all, is advocating for a shift away from the current health care payment system in the U.S., which is primarily based on fee-for-service, to a value-based payment (VBP) system.

10 Jul 2023

The causative role of age-associated pre-existing senescent cells on COVID-19 severity

Researchers investigated the role of senescent cells in the context of SARS-CoV-2 infection.

10 Jul 2023

Lilly granted MHRA marketing authorization in Great Britain for a ground-breaking UC therapy

Eli Lilly and Company announced today that the Medicines and Healthcare products Regulatory Agency (MHRA) has granted marketing authorisation (MA) for mirikizumab (OMVOH®) for the treatment of adult patients with moderately to severely active ulcerative colitis who have had an inadequate response with, lost response to, or were intolerant to either conventional therapy or a biologic treatment.

10 Jul 2023

Psilocybin-assisted therapy may provide more cost-effective solution to treating major depression disorder

A new study by leading academics in the psychedelics space finds that psilocybin combined with therapy could be more cost-effective at treating major depression disorders than currently used methods.

10 Jul 2023

Depression after TBI may not be the same as depression related to other causes, study suggests

A new study led by Shan Siddiqi, MD, from Brigham and Women’s Hospital, a founding member of the Mass General Brigham healthcare system, suggests that depression after traumatic brain injury (TBI) could be a clinically distinct disorder rather than traditional major depressive disorder, with implications for patient treatment.

10 Jul 2023

PrecisionLife licenses OXEGENE dataset to develop personalized treatments for endometriosis

PrecisionLife, a leading techbio company driving precision medicine in complex chronic diseases, announced today a data access agreement with the University of Oxford to license the Oxford Endometriosis Gene (OXEGENE) dataset with the aim to develop new personalised treatments for endometriosis patients.

10 Jul 2023

Prolonged T-cell response during severe COVID-19 does not contribute to long COVID

Persistent immune activation and elevated cytokine levels were observed in patients with severe COVID-19, even months after recovery. However, the correlation between immune activation and long COVID symptoms appeared to be independent, suggesting other factors influencing disease severity.

9 Jul 2023

Cheers or caution? Researchers question the potential benefits of alcohol consumption

Research paper discusses the relationship between alcohol consumption and health, specifically the J-shaped association. While some studies suggest this relationship, recent studies challenge it due to limitations in study design and individual variability. The paper also emphasizes the importance of considering alternative health-promoting strategies and societal/population-level harmful effects of alcohol use.

9 Jul 2023

Australian rainforest remedies: Scientists explore bioactive plant compounds as potential anti-neuroinflammatory agents

Research discusses the process of discovering anti-inflammatory and neuroprotective drugs from medicinal plants found in the Australian rainforest. It focuses on the pathways from the discovery of bioactive plants to the validation in an appropriate neuro-inflammatory mouse model, using some examples from their current research.

9 Jul 2023

New report reveals widespread, long-term impacts of Covid-19 restrictions on the poorest people

Future pandemic responses to restrict new infections need to be better balanced with allowing people to earn a living, say researchers, in a new report on the impacts of Covid-19.

8 Jul 2023

Drug-resistant pathogen found in ears of stray dogs, raising concerns about spread to humans

Scientists at McMaster University and India's University of Delhi have discovered and isolated the first live culture of the drug-resistant pathogen Candida auris from an animal, specifically from the ear canals of stray dogs.

7 Jul 2023

Study provides new insights into geographic differences in pain

The prevalence of moderate or severe joint pain due to arthritis varies strikingly across American states, ranging from 6.9% of the population in Minnesota to 23.1% in West Virginia, according to a new study led by a University at Buffalo researcher.

7 Jul 2023

Triple combination therapy shows promise in long-term treatment of cystic fibrosis

The mucus in the airways is not as sticky, inflammation in the lungs significantly reduced: Triple combination therapy can achieve these positive, lasting effects in patients with cystic fibrosis (CF).

7 Jul 2023

Ticks could be a new vector for chronic wasting disease

A new study from researchers at the University of Wisconsin–Madison finds that ticks can harbor transmissible amounts of the protein particle that causes Chronic Wasting Disease (CWD), implicating the parasites as possible agents in the disease's spread between deer in Wisconsin. Her findings were published in the journal Nature.

7 Jul 2023

Medi-Cal’s fragmented system can make moving a nightmare

When Lloyd Tennison moved from Walnut Creek to Stockton last year, he assumed his coverage under Medi-Cal, California's safety-net health insurance program, would be transferred seamlessly.

7 Jul 2023

Study: Unprocessed red meat and whole grains can be included or left out of a healthy diet

Unprocessed red meat and whole grains can be included or left out of a healthy diet, according to a study conducted in 80 countries across all inhabited continents and published today in European Heart Journal, a journal of the European Society of Cardiology.

6 Jul 2023

Chronic News and Research

The genetics of neurogenic inflammation in rosacea

Acute kidney injury does not predict worsening kidney function trajectory in CKD patients

Few studies highlight the effects of lifestyle interventions on postpartum blood pressure

Two anti-inflammatory drugs reduce deaths in severe COVID-19 patients

American Heart Association calls for shift to value-based payment system in cardiovascular care

The causative role of age-associated pre-existing senescent cells on COVID-19 severity

Lilly granted MHRA marketing authorization in Great Britain for a ground-breaking UC therapy

Psilocybin-assisted therapy may provide more cost-effective solution to treating major depression disorder

Depression after TBI may not be the same as depression related to other causes, study suggests

PrecisionLife licenses OXEGENE dataset to develop personalized treatments for endometriosis

Prolonged T-cell response during severe COVID-19 does not contribute to long COVID

Cheers or caution? Researchers question the potential benefits of alcohol consumption

Australian rainforest remedies: Scientists explore bioactive plant compounds as potential anti-neuroinflammatory agents

New report reveals widespread, long-term impacts of Covid-19 restrictions on the poorest people

Drug-resistant pathogen found in ears of stray dogs, raising concerns about spread to humans

Study provides new insights into geographic differences in pain

Triple combination therapy shows promise in long-term treatment of cystic fibrosis

Ticks could be a new vector for chronic wasting disease

Medi-Cal’s fragmented system can make moving a nightmare

Study: Unprocessed red meat and whole grains can be included or left out of a healthy diet

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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