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Data reinforces SAB-185’s potential to neutralize SARS-CoV-2 variants

A study, available on the pre-print server bioRxiv*, evaluated the neutralizing capacity of a fully human polyclonal antibody (SAB-185) against the Delta, Kappa, and Lambda variants using a lentiviral-based pseudovirus assay.

17 Aug 2021

How delta and kappa variants of SARS-CoV-2 evade the immune system

A new study, available on the bioRxiv* preprint server, describes the neutralizing ability of the monoclonal antibodies against the variants and the difference of the ACE2 binding affinity found in the variants.

17 Aug 2021

In Southeast Asia, robust immunity found up to 9 months after SARS-CoV-2 infection

Now, a new study posted to the bioRxiv* preprint server focuses on functional immune memory to SARS-CoV-2, up to nine months in a Southeast Asian cohort, in the absence of re-infection.

16 Aug 2021

Vaccinating previously infected induces more potent antibodies less susceptible to escape from SARS-CoV-2 variants

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is the causal agent of the coronavirus disease 2019 (COVID-19) pandemic, which has claimed more than 4.3 million lives worldwide. Even after implementing various measures, such as vaccination and social restrictions, SARS-CoV-2 and its variants of concern (VoC) leave the world's public health systems and economies in turmoil.

16 Aug 2021

Moderna COVID-19 vaccine safe and efficacious in adolescents according to a new study

The safety, immunogenicity, and efficacy of the vaccines in adolescents are largely unknown. Now, a new study published in the New England Journal of Medicine evaluates the safety and efficacy of the mRNA-1273 vaccine in adolescents (12-17 years of age).

16 Aug 2021

Tool for defining new SARS-CoV-2 spike nucleotide sequences to Pango lineage sets

In a recent study, a group of researchers determined the degree to which Pango lineages are distinguishable using spike-only nucleotide sequences.

16 Aug 2021

Real-time genomics to track SARS-CoV-2 help contain transmission in New Zealand

A recent study discusses how New Zealand rapidly employed real-time genomics to contain new COVID-19 cases.

16 Aug 2021

Blood clotting markers found to be elevated in patients with Long COVID syndrome

New evidence shows that patients with Long COVID syndrome continue to have higher measures of blood clotting, which may help explain their persistent symptoms, such as reduced physical fitness and fatigue.

16 Aug 2021

Obtained SARS-CoV-2 immunity, naturally or via vaccination persists 12 months

In a research paper recently uploaded to the preprint server medRxiv* by Havervall et al. (August 12th, 2021), neutralizing antibody titers towards wild-type SARS-CoV-2 and several variants of concern in individuals having either been vaccinated or infected with mild COVID-19 one year earlier are assessed, finding a reduced neutralization capacity against some strains.

16 Aug 2021

Primate study shows benefit of mRNA vaccine booster shot against SARS-CoV-2 variants

In a recent bioRxiv* preprint research paper, a large group of US scientists demonstrate how a booster dose of the mRNA-1273 vaccine can substantially improve both the potency and range of neutralizing antibody responses and mediate protection against upper and lower airway infection by a range of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern – even those relatively resistant to in vitro neutralization.

16 Aug 2021

SARS-CoV-2 Spike may trigger production of antibodies that cross-react with human thrombopoietin to induce thrombocytopenia

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infected individuals often suffer from thrombocytopenia, a condition associated with low platelet counts. The cytokine thrombopoietin regulates platelet count. Previous studies have reported that thrombocytopenia can increase the coronavirus disease 2019 (COVID-19) mortality rate by about five times.

16 Aug 2021

Research suggests toll-like receptor 4 appears to play role in severe COVID

A group of researchers re-evaluated their previously proposed hypothesis, which stated that the TLR4 activated by the spike glycoprotein S1 domain increases ACE2 expression and, thereby, aids in COVID-19 infection.

16 Aug 2021

Modeling the spread and development of SARS-CoV-2 outbreaks in the US

In a research paper recently uploaded to the medRxiv* preprint server, high-resolution contact data is utilized to characterize severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission in the USA, considering infections' mobility and seasonality and vaccination status seroprevalence within the population.

15 Aug 2021

Direct evidence in hamsters shows SARS-CoV-2 is airborne

Evidence suggests that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can be transmitted without contact by respiratory droplets and aerosols bearing the virus when coughing, sneezing, speaking, and breathing. The virus has been cultured from aerosols collected nearby COVID-19 patients, and such aerosols can linger in still air for hours.

15 Aug 2021

Syndrome News and Research

Data reinforces SAB-185’s potential to neutralize SARS-CoV-2 variants

How delta and kappa variants of SARS-CoV-2 evade the immune system

In Southeast Asia, robust immunity found up to 9 months after SARS-CoV-2 infection

Vaccinating previously infected induces more potent antibodies less susceptible to escape from SARS-CoV-2 variants

Moderna COVID-19 vaccine safe and efficacious in adolescents according to a new study

Tool for defining new SARS-CoV-2 spike nucleotide sequences to Pango lineage sets

Real-time genomics to track SARS-CoV-2 help contain transmission in New Zealand

Blood clotting markers found to be elevated in patients with Long COVID syndrome

Obtained SARS-CoV-2 immunity, naturally or via vaccination persists 12 months

Primate study shows benefit of mRNA vaccine booster shot against SARS-CoV-2 variants

SARS-CoV-2 Spike may trigger production of antibodies that cross-react with human thrombopoietin to induce thrombocytopenia

Research suggests toll-like receptor 4 appears to play role in severe COVID

Modeling the spread and development of SARS-CoV-2 outbreaks in the US

Direct evidence in hamsters shows SARS-CoV-2 is airborne

Role of neutrophil-epithelial interactions in SARS-CoV-2 infection

Utah warns of Delta variant eroding COVID vaccine effectiveness

COVID-19 prevention strategies for the U.S. food industry

Certain intestinal bacteria induce cross-reactive IgA responses to the SARS-CoV-2 spike RBD

How a hospital and a school district teamed up to help kids in emotional crisis

Discovery of highly potent neutralizing monoclonal antibodies against SARS-CoV-2

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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