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Small molecule inhibitor reverses malignant hyper-editing by an inflammation-induced protein isoform

Researchers at University of California San Diego School of Medicine, Sanford Stem Cell Institute and Moores Cancer Center report that a late-stage, pre-clinical small molecule inhibitor, called rebecsinib, reverses malignant hyper-editing by an inflammation-induced protein isoform, known as ADAR1 p150.

16 Feb 2023

Neuroscientists discover new way to disrupt chronic inflammation responsible for multiple sclerosis

UVA Health neuroscientists have discovered a potential way to disrupt the chronic inflammation responsible for multiple sclerosis.

16 Feb 2023

Similar genes may lead to different patterns of fat distribution in women

Obesity causes many health problems and worsens several chronic illnesses, including type 2 diabetes and cardiovascular disease, however, some obese people are more susceptible to complications than others.

16 Feb 2023

Study sheds light on imbalance in palliative care for non-cancer patients

Hospices and palliative care are the final chapter of life, where people spend their final days, ideally in comfort and peace.

16 Feb 2023

A call to action proposed for health providers to ensure widest distribution, easy availability of naloxone

In 2021, 100,306 Americans died from drug overdoses – a 28.5 percent increase from the prior year – with 75,673 attributed to opioids.

16 Feb 2023

HIV prevention model in Zambian prisons may be extended to other criminal justice facilities

A recent study performed in Zambia by University of Maryland School of Medicine's Institute of Human Virology researchers found that high uptake of HIV preventative medicine, known as pre-exposure prophylaxis (PrEP), is possible in prison populations with adequate resources and support from the criminal justice health system.

16 Feb 2023

As covid grabbed the world’s attention, Texas’ efforts to control TB slipped

Narciso Lopez has spent more than two decades working to control the spread of tuberculosis in South Texas.

16 Feb 2023

Study highlights the interconnectedness of autoimmunity and cancer

In a recent study published in the journal Immunity, researchers reviewed the T cell response in cancer and autoimmunity to propose strategies for more effective immunotherapies.

15 Feb 2023

Protein degradation approach can be used to hit an ‘undruggable’ target against cancer

The protein STAT5 has long been an appealing target against cancer, but after decades of research it was consigned to the "undruggable" category.

15 Feb 2023

Sleep irregularity may increase the risk for atherosclerosis

Sleep irregularity - chronically disrupted sleep and highly variable sleep durations night after night - may increase the risk for atherosclerosis, according to a study led by Kelsie Full, PhD, MPH, of Vanderbilt University Medical Center.

15 Feb 2023

Irregular sleeping habits linked to atherosclerosis risk in older adults

Sleeping an inconsistent number of hours each night and falling asleep at different times may increase the risk of developing atherosclerosis among adults older than 45 compared to people with more consistent sleep habits, according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

15 Feb 2023

What is the tolerability profile and rate of recurrent CDI after administrating microbiome therapeutic SER-109 post-antibiotic treatment?

Researchers investigated the tolerability and safety of a microbiome therapy called SER-109 to treat recurrent infections of Clostridioides difficile in adults.

15 Feb 2023

Rapid clinical test predicts which people with neck pain may benefit from epidural steroid injections

Researchers from Johns Hopkins Medicine and several other institutions say they have developed a quick clinical test that predicts which people with neck pain are more likely to benefit from epidural steroid injections, which deliver drugs directly around the spinal nerves to stop nerve inflammation and reduce pain.

15 Feb 2023

What is the relationship between the pattern of alcohol consumption and subjective quality of life in healthy adults?

Researchers assessed the impact of moderate alcohol consumption on the QoL in young adults.

15 Feb 2023

Study on modern diets and how they impact the environment

A review article published in the journal Nutrients describes the impact of six popular diets on human health as well as planetary health. The health and environmental impacts of these diets have been compared in the review using carbon footprint databases and representative meal plans.

14 Feb 2023

Alternate-day fasting diet and exercise benefit the health of people with nonalcoholic fatty liver disease

Nutrition researchers at the University of Illinois Chicago studied 80 people with nonalcoholic fatty liver disease and found that those who followed an alternate-day fasting diet and exercised were able to improve their health.

14 Feb 2023

Fibromyalgia may occur post-COVID

Researchers investigate the incidence of fibromyalgia among individuals hospitalized due to SARS-CoV-2 infection.

14 Feb 2023

High prevalence and risks of heart failure warrant urgent action, say researchers

Up to 2% of adults in Europe, North America, and Israel likely have heart failure, and are at high risk of death and additional serious complications, suggest current estimates based on digital health records for 11 countries, and published online in the journal Heart.

14 Feb 2023

In California, Democrats propose $25 minimum wage for health workers

Union-aligned Democrats were set to introduce legislation Wednesday mandating a statewide $25 minimum wage for health workers and support staffers, likely setting up a pitched battle with hospitals, nursing homes, and dialysis clinics.

14 Feb 2023

Sylvester Comprehensive Cancer Center researcher receives $1.4 million to help construction workers quit smoking

The Florida Department of Health recently awarded more than $1.4 million from the James and Esther King Biomedical Research Program to Taghrid Asfar, M.D., at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine, to help construction workers quit smoking.

14 Feb 2023

Chronic News and Research

Small molecule inhibitor reverses malignant hyper-editing by an inflammation-induced protein isoform

Neuroscientists discover new way to disrupt chronic inflammation responsible for multiple sclerosis

Similar genes may lead to different patterns of fat distribution in women

Study sheds light on imbalance in palliative care for non-cancer patients

A call to action proposed for health providers to ensure widest distribution, easy availability of naloxone

HIV prevention model in Zambian prisons may be extended to other criminal justice facilities

As covid grabbed the world’s attention, Texas’ efforts to control TB slipped

Study highlights the interconnectedness of autoimmunity and cancer

Protein degradation approach can be used to hit an ‘undruggable’ target against cancer

Sleep irregularity may increase the risk for atherosclerosis

Irregular sleeping habits linked to atherosclerosis risk in older adults

What is the tolerability profile and rate of recurrent CDI after administrating microbiome therapeutic SER-109 post-antibiotic treatment?

Rapid clinical test predicts which people with neck pain may benefit from epidural steroid injections

What is the relationship between the pattern of alcohol consumption and subjective quality of life in healthy adults?

Study on modern diets and how they impact the environment

Alternate-day fasting diet and exercise benefit the health of people with nonalcoholic fatty liver disease

Fibromyalgia may occur post-COVID

High prevalence and risks of heart failure warrant urgent action, say researchers

In California, Democrats propose $25 minimum wage for health workers

Sylvester Comprehensive Cancer Center researcher receives $1.4 million to help construction workers quit smoking

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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