in vitro News and Research

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Real-time molecule-by-molecule "movie" of protein production in live cells

Chemists at Harvard University have developed the first technique providing a real-time, molecule-by-molecule "movie" of protein production in live cells.

19 Mar 2006

Researchers find viable new sources for stem cell transplants to the heart

Stem cell transplantation is among one of the most exciting and hotly debated areas of medical research today. While the promise of personalized medicine and effective treatments for debilitating diseases drive progress in this area, moral and ethical dilemmas about embryonic cells continues to cloud the field.

14 Mar 2006

Anti-inflammatory effect of beer

Scientists at Innsbruck Medical University have succeeded in demonstrating the anti-inflammatory effect of beer extracts.

6 Mar 2006

Hydrogel scaffold materials used to create stable networks of blood vessels

Yale biomedical engineers have created an implantable system that can form and stabilize a functional network of fine blood vessels critical for supporting tissues in the body, according to a report in the Proceedings of the National Academy of Sciences.

1 Mar 2006

Researchers edge closer to cardiac tissue engineering

Researchers have developed a method to engineer blood vessels within the tissue of previously engineered heart muscle. Trials have resulted in significant improvement in heart function.

1 Mar 2006

Man-made heart tissue improves heart function

Researchers have developed a method to engineer blood vessels within the tissue of previously engineered heart muscle. Trials have resulted in significant improvement in heart function.

27 Feb 2006

New tool to discover molecules that can enhance or block different kinds of tastes

Researchers from the Monell Chemical Senses Center have succeeded in growing mature taste receptor cells outside the body and for the first time have been able to successfully keep the cells alive for a prolonged period of time.

27 Feb 2006

New tool helps predict pregnancy outcomes

Physicians must consider a number of variables when treating couples who cannot naturally conceive because of factors involving both the woman and man.

23 Feb 2006

New understanding of the molecular genetics of successful fertilization

A new paper in the February 15th issue of Genes & Development lends novel insight into the cellular changes that occur in sperm while they reside in the female reproductive tract - providing a new understanding of the molecular genetics of successful fertilization.

14 Feb 2006

Statins show beneficial effect on rheumatoid arthritis

Statins, a class of drugs widely used to treat high cholesterol, have also recently been studied for their potential role in inflammation and other cell processes, including immune response.

13 Feb 2006

Rett disease progression altered by changing expression of gene

Scientists from the Whitehead Institute for Biomedical Research, Brandeis University and Massachusetts Institute of Technology report in the journal Neuron that increasing levels of brain derived neurotrophic factor (BDNF) alleviates symptoms in a mouse model of the childhood disorder Rett Syndrome.

13 Feb 2006

Nod1 found to control tumor growth in certain breast cancers

This protein was previously thought to play a role solely in the innate immune system's response to bacterial infection. In the new study, which will be published on-line by the Proceedings of the National Academy of Sciences

12 Feb 2006

Changes in the tissue environment of the breast that occur after pregnancy promote the metastasis of breast tumor cells

Changes in the tissue environment of the breast that occur after pregnancy promote the metastasis of breast tumor cells. The paper by McDaniel et al., "Remodeling of the mammary microenvironment following lactation promotes breast tumor cell metastasis.

12 Feb 2006

Discovery of the molecular mechanism that inhibits HCV replication in vitro

Since its discovery several decades ago, the insidious human pathogen has stymied the quest for anti-viral therapies by refusing to reproduce in test tubes for more than a few hours or days, denying scientists an efficient virus production and infection system for experimental research.

7 Feb 2006

FDA grants fast track status for ViroPharma's Maribavir

ViroPharma Incorporated has announced that the U.S. Food and Drug Administration (FDA) has granted fast track designation for maribavir, an oral antiviral drug candidate for the prevention of cytomegalovirus (CMV) infection in allogeneic bone marrow (stem cell) and solid organ transplant patients.

7 Feb 2006

Viragen reports on Multiferon anti-viral studies

Viragen, Inc today reported on the progression of anti-viral studies using Multiferon (multi-subtype, natural human alpha interferon) being conducted by the U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID).

7 Feb 2006

Myosin VI can act as molecular transporter

Myosin VI has been thought to be a monomer, but Park et al. show that full-length myosin VI can be a dimer, and can walk processively on actin. By increasing the concentration, a greater and greater fraction dimerizes in vitro, and walks processively on actin.

7 Feb 2006

Preimplantation cell number may affect birthweight

Dr Lieberman et al. at the Department of Obstetrics, Gynaecology and Reproductive Biology at the Brigham and Women's Hospital, Harvard Medical School in Boston, USA have measured the quality of human embryos by counting and assessing the properties of their individual cells.

2 Feb 2006

Oocyte cryopreservation - allows women to freeze their eggs

Researchers at the Yale Fertility Center are now offering a cutting edge reproductive procedure called oocyte cryopreservation that allows women to freeze their eggs and use them at a later time to conceive a child.

27 Jan 2006