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Chinese scientists clone a goat

It was released on August 24, 2005 by Prof. Chen Dayuan (Da-Yuan Chen) from the CAS Institute of Zoology that the first success in cloning Asian Yellow Goat by nuclear transfer had recently been achieved in east China's Shandong Province.

6 Sep 2005

Naturally occurring peptide hormones - candidates for the treatment of cancer, sexual dysfunction, eating disorders

Chemists at the University of Arizona have developed modified versions of naturally occurring peptide hormones that could be key to novel treatments of a variety of diseases, including eating disorders (anorexia, obesity), diabetes, sexual dysfunction and skin cancer.

1 Sep 2005

Pomegranate fruit extracts can block enzymes that contribute to osteoarthritis

The study looked at the ability of an extract of pomegranate fruit against Interleukin-1b (IL-1b), a pro-inflammatory protein molecule that plays a key role in cartilage degradation in osteoarthritis.

1 Sep 2005

Virginia Tech engineer investigates enzyme link to Huntington's, Parkinson's, and Alzheimer diseases

Several neurologically based afflictions, such as Huntington's, Parkinson's, and Alzheimer diseases, have been correlated to a higher than normal presence of a specific type of enzymes, called transglutaminases (TGase) in the human body.

30 Aug 2005

Inhibitory systems essential for controlling the pattern of activity in the cortex

Inhibitory systems are essential for controlling the pattern of activity in the cortex, which has important implications for the mechanisms of cortical operation, according to a Yale School of Medicine study in Neuron.

28 Aug 2005

Lorus identifies novel class of lead drug candidates from small molecule anticancer program

Lorus Therapeutics has announced the continued success in the development of its small molecule anticancer program with the selection of a sub-class of lead molecules from the Company's small molecule program.

24 Aug 2005

New study points to new treatments for some forms of Lou Gehrig's disease

A new study indicates that mutant Cu/Zn superoxide dismutase (SOD1) enzymes that are associated with an inherited form of Lou Gehrig's disease cause the protein to become sticky in tissues. Partial unfolding of the mutant protein can expose hydrophobic residues that may promote abnormal interactions with other proteins or membranes in the cell.

11 Aug 2005

Lifestyle changes may affect the progression of any type of cancer

Men with early stage prostate cancer who make intensive changes in diet and lifestyle may stop or perhaps even reverse the progression of their illness, according to a new study.

11 Aug 2005

Genelabs drug discovery team advances compounds against the hepatitis C virus

Genelabs Technologies today announced that a non-nucleoside compound from its internal Hepatitis C virus (HCV) drug discovery program has advanced into preclinical development.

4 Aug 2005

Strategic analyses of European In-Vitro cancer diagnostics market - Cancer research yields promising results

Every year, nearly one in four Europeans - a total of almost one million people - dies from cancer, giving Europe the dubious distinction of having amongst the highest cancer-related mortality rates in the world. Even as cancer remains a difficult disease to diagnose, often resulting in either poor diagnosis or misdiagnosis, the number of new cancer cases is set to double by 2020.

2 Aug 2005

IVF treatment to restrict women to one embryo only each time

In order to avoid the dangers of multiple births, women having in vitro fertilisation may be limited to having just one embryo implanted at a time.

29 Jul 2005

In vivo engineering of organs: The bone bioreactor

An international team of biomedical engineers has demonstrated for the first time that it is possible to grow healthy new bone reliably in one part of the body and use it to repair damaged bone at a different location.

25 Jul 2005

Fertility drugs may be ineffective for women who lack a gene called the estrogen receptor beta

"What we found is that the beta estrogen receptor plays a role in moving the egg outside the ovary so it can be fertilized," said Kenneth Korach, Ph.D., Laboratory Chief at the National Institute of Environmental Health Sciences (NIEHS) where the research was conducted. "We never knew before what function this receptor played in reproduction."

20 Jul 2005

Spontaneous contractions suppressed in late-term rat pregnancy

A long-time aim of obstetrical research has been to find agents that could delay or diminish pre-term labor because even today pre-term birth is a leading cause of infant mortality and morbidity.

19 Jul 2005

FDA fast tracks HIV protease inhibitor from Vertex and GSK

Vertex Pharmaceuticals has announced that its collaborator, GlaxoSmithKline (GSK), has received fast track designation for the HIV protease inhibitor (PI) 640385 (VX-385) from the United States Food and Drug Administration.

19 Jul 2005

Novel way in which the brain size of developing mammals may be regulated

Howard Hughes Medical Institute researchers have discovered a novel way in which the brain size of developing mammals may be regulated. They have identified a signaling pathway that controls the orientation in which dividing neural progenitor cells are cleaved during development.

14 Jul 2005

Viagra's non-blood pressure effect successfully mimics vasopressin action

Normally your kidneys filter about 50 gallons of blood a day, remove such waste as salts and minerals, and concentrate it into urine. When you exercise or don't take in water, your blood "thickens" and instead of removing water, the kidney reverses the process, pulls in water from the body that would normally go into the urine, and puts it into the blood, thus maintaining water balance.

29 Jun 2005

Uncomplicated twin pregnancies might be more risky than previously thought

As mothers get older and assisted conception becomes more common, the incidence of multiple births - primarily of nonidentical siblings, but also of identical ones - has dramatically increased.

28 Jun 2005

Study causes big shift in how we think about p53 gene

The cellular cascade of molecular signals that instructs cells with fatally damaged DNA to self-destruct pivots on the p53 tumor suppressor gene. If p53 is inactivated, as it is in over half of all human cancers, checks and balances on cell growth fail to operate, and body cells start to accumulate mutations, which ultimately may lead to cancer.

27 Jun 2005

High-tech infertility treatment for men most common therapy to help couples conceive

According to recently released figures, a high tech treatment for male infertility has become the most common therapy in Europe to help couples conceive.

23 Jun 2005