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Inflammation plays a key role in resolving pain

In a recent study published in the journal Science Translational Medicine, researchers explored the mechanisms underlying the transition from acute to chronic low back pain (LBP) by transcriptome-wide analysis of peripheral immune cells from acute LBP patients.

17 May 2022

Mice live longer with nasal gene therapy

In a recent study published in the Proceedings of the National Academy of Sciences journal, researchers assessed the efficiency of a novel intranasal and injectable therapy in improving life expectancy.

17 May 2022

Why do diabetic patients have more severe SARS-CoV-2 infections?

A recent study published in the journal Cell Metabolism illustrated the function of angiotensin-converting enzyme 2 (ACE2) in renal severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection among diabetic patients.

16 May 2022

Malaria eradication calls for detection and treatment of asymptomatic cases

Asymptomatic malaria infections do not reduce the risk of severe disease, as widely believed, but suppress the immune system and prevent it from getting rid of parasites that persist in the bloodstream, research suggests.

16 May 2022

Black children have the highest risk of both PICU admission and mortality, study finds

Hospitalized children covered by Medicaid who reside in the poorest neighborhoods are at increased risk of being admitted to the hospital's Pediatric Intensive Care Unit (PICU) and of dying while there, according to research published at the ATS 2022 international conference.

16 May 2022

Removing air pollution emissions would prevent more than 50,000 premature deaths

Eliminating air pollution emissions from energy-related activities in the United States would prevent more than 50,000 premature deaths each year and provide more than $600 billion in benefits each year from avoided illness and death, according to a new study by University of Wisconsin–Madison researchers.

16 May 2022

New AI tool can speed up the diagnosis of psoriatic arthritis by up to 4 years

Researchers in Israel have shown that a new machine-learning tool can speed up the diagnosis of psoriatic arthritis (PsA) by up to 4 years, potentially preventing irreversible joint damage and deteriorating function for sufferers.

15 May 2022

Researchers identify how the brain triages emotions during dream sleep

Researchers at the Department of Neurology of the University of Bern and University Hospital Bern identified how the brain triages emotions during dream sleep to consolidate the storage of positive emotions while dampening the consolidation of negative ones.

13 May 2022

Study shows how co-transplanting islet cells with SA-FasL-microgels reverses diabetic symptoms

Islet cell transplants are a promising treatment that can cure difficult-to-treat type 1 diabetes. The cells, taken from a donor pancreas, provide patients with a sustainable and tightly controlled source of insulin.

13 May 2022

New discovery has potential to stop inflammation at the "growing end"

Redness, swelling, pain - these are signs of inflammation. It serves to protect the body from pathogens or foreign substances.

13 May 2022

New mouse model shows the connection between stress, depression and cardiovascular disease risk

Results from a new mouse model may aid in understanding how depression and prolonged and severe stress increase the risk of cardiovascular disease, according to preliminary research presented at the American Heart Association's Vascular Discovery: From Genes to Medicine Scientific Sessions 2022.

13 May 2022

The association between modifiable healthy lifestyle components and lifetime gain in the general Japanese population

In a recent paper posted to the Age and Ageing, investigators illustrated the effect of adopting a changeable healthy lifestyle on lifetime gains from middle to old age.

13 May 2022

Chronic obstructive pulmonary disease leads to premature senescence of the immune system

A study conducted at the University of São Paulo's Medical School (FM-USP) in Brazil, with results reported in an article published in the journal Immunity & Ageing, shows that chronic obstructive pulmonary disease (COPD) leads to premature senescence (age-related impairment) of the immune system.

13 May 2022

Adolescent and young adult leukemia survivors have reduced long-term survival compared to peers without cancer

Researchers at The University of Texas MD Anderson Cancer Center have discovered that adolescent and young adult (AYA) cancer survivors of acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML) have reduced long-term survival rates compared to their peers without cancer.

13 May 2022

Lean people with NAFLD more likely to have cardiovascular disease than those who are overweight

Those with a normal body mass index (BMI) with non-alcoholic fatty liver disease (NAFLD) are more likely to have cardiovascular disease than those who are overweight or living with obesity, according to research selected for presentation at Digestive Disease Week 2022.

13 May 2022

Analysis reveals increasing prevalence of esophageal cancer and Barrett’s esophagus in middle-aged adults

Adults aged 45 to 64 experienced a nearly doubled rate of esophageal cancer and a 50 percent increase in the precancerous condition Barrett's esophagus between 2012 and 2019, according to a database analysis of roughly five million patients to be presented at Digestive Disease Week 2022.

13 May 2022

Hormonal shift during menopause changes women’s blood metabolite profile

In midlife, the risk of cardiometabolic diseases increases in women more rapidly than in men. A study performed at the Faculty of Sport and Health Sciences of the University of Jyväskylä shows that changes in blood metabolite profile accompany the shift in sex hormone levels during menopause.

13 May 2022

Enzyme discovery offers new way to regulate cell death process for inflammatory diseases

A WEHI-led study has identified a new enzyme involved in controlling cell death, in findings that could lead to better treatment options for a range of inflammatory conditions, cancers and viruses.

12 May 2022

Study examines the causal effect of high fertility on late-life cognition

A new study at Columbia University Mailman School of Public Health, and the Robert Butler Columbia Aging Center and Université Paris-Dauphine – PSL, found that having three or more versus two children has a negative effect on late-life cognition.

12 May 2022

Mitochondrial respiratory chain is essential for NLRP3 inflammasome activation

Northwestern Medicine investigators recently discovered that the mitochondrial respiratory chain — a series of protein complexes essential for a cellular respiration and energy production — is necessary for the activation of another protein complex linked to inflammation and the progression of chronic diseases, according to a study published in Nature Immunology.

12 May 2022

Chronic News and Research

Inflammation plays a key role in resolving pain

Mice live longer with nasal gene therapy

Why do diabetic patients have more severe SARS-CoV-2 infections?

Malaria eradication calls for detection and treatment of asymptomatic cases

Black children have the highest risk of both PICU admission and mortality, study finds

Removing air pollution emissions would prevent more than 50,000 premature deaths

New AI tool can speed up the diagnosis of psoriatic arthritis by up to 4 years

Researchers identify how the brain triages emotions during dream sleep

Study shows how co-transplanting islet cells with SA-FasL-microgels reverses diabetic symptoms

New discovery has potential to stop inflammation at the "growing end"

New mouse model shows the connection between stress, depression and cardiovascular disease risk

The association between modifiable healthy lifestyle components and lifetime gain in the general Japanese population

Chronic obstructive pulmonary disease leads to premature senescence of the immune system

Adolescent and young adult leukemia survivors have reduced long-term survival compared to peers without cancer

Lean people with NAFLD more likely to have cardiovascular disease than those who are overweight

Analysis reveals increasing prevalence of esophageal cancer and Barrett’s esophagus in middle-aged adults

Hormonal shift during menopause changes women’s blood metabolite profile

Enzyme discovery offers new way to regulate cell death process for inflammatory diseases

Study examines the causal effect of high fertility on late-life cognition

Mitochondrial respiratory chain is essential for NLRP3 inflammasome activation

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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