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Host viral burden increases with age, is reduced by vaccination, and is influenced by vaccination status and viral variant interplay

The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants on host viral burden.

18 Aug 2023

Regulation of cytotoxic T-cell differentiation and exhaustion by mTOR signaling

Researchers describe molecular signalling regulated by mTOR among memory and exhausted cytotoxic CD8+ T lymphocytes.

18 Aug 2023

Next-generation sequencing provides novel insights into the mechanisms underlying autism and myotonic muscular dystrophy

The pathomechanistic connection between autism and myotonic muscular dystrophy type 1.

16 Aug 2023

Study uses genomic data to produce high-resolution serial interval estimates for COVID-19

Researchers developed an approach for integrating whole-genomic viral sequences and epidemiological information for serial interval (SI) estimation.

16 Aug 2023

Study shows how brain rhythms can affect brain function by altering microglia and cytokines

Researchers used visual flickering sensory stimulation to reveal the underlying mechanisms governing microglial morphology and cytokine expression in mice.

16 Aug 2023

Epigenetic manipulation may improve breast cancer treatment responses

Researchers explore the possibility of increasing TROP2 ADC activity by enhancing the expression of TROP2 on cancer cells.

15 Aug 2023

Is COVID-19 self-testing effective?

Real-world evidence on the performance of coronavirus disease 2019 (COVID-19) self-testing strategies.

15 Aug 2023

Study finds way to reverse gene silencing in inner ear cells

A deafened adult cannot recover the ability to hear, because the sensory hearing cells of the inner ear don't regenerate after damage.

14 Aug 2023

Trained scent dogs can more effectively detect COVID-19 infections than RT-PCR tests

It's an idea that has finally gained scientific consensus: Dogs can be a faster, more precise, less expensive - not to mention friendlier - method of detecting COVID-19 than even our best current technology.

14 Aug 2023

UAB researchers identify cell-surface marker that indicates fate of T cells

Follicular helper T cells, or Tfh cells, have a crucial role in immune defense. Without Tfh cells, B cells cannot form germinal center, or GC, responses during which high-affinity antibodies are generated.

14 Aug 2023

Research illustrates the role of Gasdermin D protein in immunity tolerance to food

A research team led by Prof. ZHU Shu from the University of Science and Technology of China (USTC) of the Chinese Academy of Sciences (CAS) illustrated the role of Gasdermin D (GSDMD) protein in immunity tolerance to food in the small intestine.

11 Aug 2023

New mechanism discovered for brain repair after ischemic stroke

Patients often experience functional decline after an ischemic stroke, especially due to the brain's resistance to regenerate after damage.

10 Aug 2023

Scientists develop "universal pan-mammalian clock" to accurately estimate age in mammals

Scientists at UCLA David Geffen School of Medicine and UCLA Health led an international research team that published two articles detailing changes in DNA – changes that researchers found are shared by humans and other mammals throughout history and are associated with life span and numerous other traits.

10 Aug 2023

Autism spectrum disorder may be linked to imbalance of neurons in the brain

Using human "mini-brain" models known as organoids, Mayo Clinic and Yale University scientists have discovered that the roots of autism spectrum disorder may be associated with an imbalance of specific neurons that play a critical role in how the brain communicates and functions.

10 Aug 2023

Transcription News and Research

Host viral burden increases with age, is reduced by vaccination, and is influenced by vaccination status and viral variant interplay

Regulation of cytotoxic T-cell differentiation and exhaustion by mTOR signaling

Next-generation sequencing provides novel insights into the mechanisms underlying autism and myotonic muscular dystrophy

Study uses genomic data to produce high-resolution serial interval estimates for COVID-19

Study shows how brain rhythms can affect brain function by altering microglia and cytokines

Epigenetic manipulation may improve breast cancer treatment responses

Is COVID-19 self-testing effective?

Study finds way to reverse gene silencing in inner ear cells

Trained scent dogs can more effectively detect COVID-19 infections than RT-PCR tests

UAB researchers identify cell-surface marker that indicates fate of T cells

Research illustrates the role of Gasdermin D protein in immunity tolerance to food

New mechanism discovered for brain repair after ischemic stroke

Scientists develop "universal pan-mammalian clock" to accurately estimate age in mammals

Autism spectrum disorder may be linked to imbalance of neurons in the brain

Newly identified helicase might hold the key to a novel family of anti-COVID-19 drugs

Preventing the next pandemic: swine influenza genomic surveillance essential, study shows

Study explores the diverse expression patterns of T cell priming markers across cancers

Exploring molecular mechanisms and genetic dysregulation in aging and age-associated diseases

CDK9 inhibitors: A promising new treatment for hematological malignancies

Effect of mutations in cancer-driving genes across human cancers

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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