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Algorithmic clustering by pain distribution may help personalize chronic pain management

Pain distribution as reported on a body map, on its own, can be used to assign patients to distinct subgroups that are associated with differences in pain intensity, pain quality, pain impact and clinically-relevant three-month outcomes, according to a new study published this week in the open-access journal PLOS ONE by Benedict Alter of University of Pittsburgh, US, and colleagues.

4 Aug 2021

Nutritional value of foods has not improved despite targets for reductions in salt, sugar and calories

UK policies that set targets for reductions in salt, sugar and calories have not led to overall improvements in the nutritional value of food products.

4 Aug 2021

Drug-eluting endotracheal tubes for preventing airway complications

In a proof-of-concept study, researchers at Children's Hospital of Philadelphia have created a coating that can be applied to endotracheal tubes and release antimicrobial peptides that target infectious bacteria with specificity.

4 Aug 2021

Non-invasive brain stimulation may reduce smoking frequency in nicotine-dependent smokers

A new systematic review of randomized controlled trials has found evidence that non-invasive brain stimulation may reduce smoking frequency (number of cigarettes per day) in nicotine-dependent smokers.

4 Aug 2021

Simple text messages can increase COVID-19 vaccine uptake

New UCLA-led research indicates that simple text messages emphasizing the easy availability of COVID-19 vaccines successfully boosted the number of people who got the shot.

4 Aug 2021

Common weight-loss drug successfully targets fat in adults with obesity at high cardiovascular risk

Researchers at UT Southwestern announced successful results of a clinical trial for a commonly prescribed weight-loss drug called liraglutide.

4 Aug 2021

Flu vaccine may provide vital protection against COVID-19, study shows

In a newly published study, physician-scientists at the University of Miami Miller School of Medicine have shown that the flu vaccine may provide vital protection against COVID-19.

4 Aug 2021

Key protein linked to both physical fitness in youth and diseases of old age

Researchers from Johns Hopkins Medicine say they have added to evidence that a protein called CaMKII improves strength, endurance, muscle health and fitness in young animals.

4 Aug 2021

Economic mobility associated with racial mortality gaps in the United States

A new study suggests structural racism measured by the racial economic mobility gap between Black and White persons with a similar parental income (as an indicator of similar childhood socioeconomic status) is strongly associated with Black-White disparities in mortality in the United States, both in a recent birth cohort and in all ages combined.

4 Aug 2021

Research: Only 26% of areas in the UK have an effective pathway in place for early liver disease detection

New research published today in a peer review journal shows only 26% of areas in the UK have an effective pathway in place for the early detection of liver disease.

4 Aug 2021

New molecular and morphologic insights into chronic rejection after lung transplantation

A study of lung tissue from patients with end-stage bronchiolitis obliterans syndrome (BOS) as a complication of lung transplantation yielded molecular and morphologic insights into the development of chronic rejection.

3 Aug 2021

Flagging potential molecular predictors of response to biological therapies in ulcerative colitis

Several individuals suffering from bowel diseases like ulcerative colitis fail to respond to conventionally used biologic therapies.

3 Aug 2021

Study shows increased risk of overdose and mental health crisis following opioid dose tapering

Opioid therapy is complex. In recent years, a rise in opioid-related deaths and changing prescribing guidelines and regulatory policies have led many physicians to reduce daily doses for patients prescribed stable opioid therapy for chronic pain.

3 Aug 2021

Study sheds light on oral vaccine failure in mouse model of chronic gut disorder

A chronic gut disorder that occurs in regions with poor sanitation disrupts intestinal immune responses and impairs oral vaccine effectiveness in a mouse model of the disease, according to research led by UPMC Children's Hospital of Pittsburgh and University of Pittsburgh School of Medicine scientists.

3 Aug 2021

Novel type of cellular therapy safe for knee pain caused by osteoarthritis, study confirms

A study released in STEM CELLS Translational Medicine has confirmed the safety of a novel type of cellular therapy for knee pain caused by osteoarthritis.

3 Aug 2021

Analysis: Keto diets place pregnant women and kidney disease patients at risk of adverse health effects

In the most comprehensive analysis yet of ketogenic (keto) diets, a review in Frontiers in Nutrition finds keto diets place pregnant women and kidney disease patients at risk of adverse health effects.

3 Aug 2021

Hormone-resistant prostate, breast cancers added to clinical trial of experimental DNA therapy

The Republic of Belarus Ministry of Health has approved expanding the ongoing clinical trial of CureLab Oncology's Elenagen, an experimental DNA therapy, to include two new arms: 1) hormone-resistant breast cancer; and 2) hormone-resistant metastatic prostate cancer.

3 Aug 2021

CHOP researchers identify two proteins that could be used for a potential NTHi vaccine

Scientists at Children's Hospital of Philadelphia have identified two proteins that could be used for a potential vaccine against nontypeable Haemophilus influenzae (NTHi).

2 Aug 2021

New model can help clinicians to predict 40-day mortality risk in hospitalized COVID-19 patients

Researchers from Hackensack Meridian University Medical Center and Berry Consultants, LLC, Austin, Texas have developed a new model to help clinicians predict the risk of death within 40 days in patients who are hospitalized with COVID-19 infection.

2 Aug 2021

Customized, biomedically applicable materials based on tropoelastin for wound care

Customized, biomedically applicable materials based on tropoelastin are being developed in a joint project by Skinomics GmbH from Halle, Martin Luther University Halle-Wittenberg and the Fraunhofer Institute for Microstructure of Materials and Systems IMWS.

2 Aug 2021

Chronic News and Research

Algorithmic clustering by pain distribution may help personalize chronic pain management

Nutritional value of foods has not improved despite targets for reductions in salt, sugar and calories

Drug-eluting endotracheal tubes for preventing airway complications

Non-invasive brain stimulation may reduce smoking frequency in nicotine-dependent smokers

Simple text messages can increase COVID-19 vaccine uptake

Common weight-loss drug successfully targets fat in adults with obesity at high cardiovascular risk

Flu vaccine may provide vital protection against COVID-19, study shows

Key protein linked to both physical fitness in youth and diseases of old age

Economic mobility associated with racial mortality gaps in the United States

Research: Only 26% of areas in the UK have an effective pathway in place for early liver disease detection

New molecular and morphologic insights into chronic rejection after lung transplantation

Flagging potential molecular predictors of response to biological therapies in ulcerative colitis

Study shows increased risk of overdose and mental health crisis following opioid dose tapering

Study sheds light on oral vaccine failure in mouse model of chronic gut disorder

Novel type of cellular therapy safe for knee pain caused by osteoarthritis, study confirms

Analysis: Keto diets place pregnant women and kidney disease patients at risk of adverse health effects

Hormone-resistant prostate, breast cancers added to clinical trial of experimental DNA therapy

CHOP researchers identify two proteins that could be used for a potential NTHi vaccine

New model can help clinicians to predict 40-day mortality risk in hospitalized COVID-19 patients

Customized, biomedically applicable materials based on tropoelastin for wound care

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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