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Histamine boost helps the brain remember, decide, and learn from loss

Pitolisant, a histamine H3 receptor inverse agonist, improved recognition memory, working memory performance, and reinforcement learning in healthy adults. The findings suggest that histamine helps shape how the brain stabilizes new memories, accumulates evidence for decisions, and avoids overreacting to negative outcomes.

3 Jun 2026

New all-oral regimen improves treatment convenience for AML patients

The ASCERTAIN V clinical trial demonstrated that an all-oral drug combination for older patients with acute myeloid leukemia (AML) is an effective alternative to the current standard, which requires repeated hospital or office visits for intravenous treatment.

3 Jun 2026

Novel CAR T treatment makes previously impossible kidney transplants possible

A pioneering clinical trial has successfully enabled two patients with end-stage kidney disease to receive previously improbable kidney transplants.

3 Jun 2026

Patented technology enables real-time detection of surgical bleeding sources

The United States Patent and Trademark Office (USPTO) officially issued a new patent to Wayne State University and RediMinds Inc. of Southfield, Michigan. The patent protects a pioneering technological advancement developed in the university's laboratories.

3 Jun 2026

Higher genetic pulse pressure risk associated with dementia-related mortality

When looking at genetic variants in a person's DNA that predispose them to disease, a new study has found having a higher number of genetic variants for increased pulse pressure is associated with a small, increased risk of dementia as a contributing cause of death.

3 Jun 2026

Air pollution below EPA thresholds still poses heart health risks

Air pollution does not have to exceed federal limits to potentially harm human health, according to a new review published in Environmental Pollution.

3 Jun 2026

What pregnancy reveals about a woman’s future heart health

Pregnancy acts as a natural cardiovascular stress test, revealing hidden heart disease and identifying women at higher long-term risk after complications such as preeclampsia, gestational diabetes, and preterm birth. The review highlights major evidence gaps in cardio-obstetric care and calls for stronger postpartum screening, dedicated women’s health clinics, and better inclusion of reproductive-age women in research.

3 Jun 2026

New study reevaluates stroke risk for female patients with atrial fibrillation

A new Tulane University study challenges a long-standing assumption in heart care: that being female automatically increases stroke risk for patients with atrial fibrillation, a common condition that causes the heart to beat irregularly.

3 Jun 2026

New technique protects pancreatic islet transplants without immunosuppressive drugs

Type 1 diabetes (T1D) is a lifelong autoimmune disorder where the immune system attacks islets, certain areas of the pancreas, and destroys cells that would otherwise produce insulin, a hormone crucial for regulating blood sugar levels.

3 Jun 2026

CAR-T cell therapy shows promise for treating rheumatoid arthritis

Current therapies for rheumatoid arthritis rely on sustained immunosuppression rather than restoration of immune tolerance, with off-drug remission remaining rare.

3 Jun 2026

Brain tumor removal may improve blood sugar in diabetes patients

A new study published today in JAMA Network Open found that removing olfactory groove meningioma - a type of brain tumor located near the base of the brain - may improve blood sugar control in patients with diabetes.

3 Jun 2026

Early paracetamol may speed up heart vessel closure in preterm babies

Early administration of paracetamol may accelerate closure of the patent ductus arteriosus in extremely preterm babies, according to a new study.

3 Jun 2026

Scientists mimic heart cell signaling using organic conductive plastics

For the first time, scientists have succeeded in artificially mimicking the ion signaling of heart muscle cells.

3 Jun 2026

Aspirin use may help unmask early asymptomatic bladder cancer

The presence of blood cells in urine is a sign of bladder cancer. Because aspirin blocks platelets from forming harmful blood clots, the medication can cause mild bleeding or worsen existing bleeding in the urinary tract.

3 Jun 2026

Genetically-modified hookworms successfully deliver medicine to animal hosts

Hookworms, intestinal parasites that infect hundreds of millions of people in under-resourced tropical regions around the globe, have evolved to survive inside the human gut for years, secreting molecules that enable co-existence with their hosts.

3 Jun 2026

Giving antibiotics for throat infections overrates their power against sepsis

Antibiotics for sore throats have hardly any preventive effect against serious streptococcal infections in the population, according to a study from the University of Gothenburg.

3 Jun 2026

GLP-1 therapy linked to slower biological aging processes

Glucagon-like peptide-1 (GLP-1) receptor agonist medications have gained widespread attention for effectively treating obesity, lowering blood sugar and decreasing the risk of cardiovascular disease.

2 Jun 2026

Three-drug strategy forces pancreatic tumors into lasting regression

A triple-targeted preclinical therapy combining daraxonrasib, afatinib, and SD36 drove durable pancreatic cancer regression by blocking KRAS/RAS, EGFR/HER2, and STAT3 signaling. The approach prevented treatment resistance across mouse and human tumor-derived models, but remains preclinical and requires more clinically suitable drug combinations before human testing.

2 Jun 2026

AI turns everyday smartphone use into passive heart-rate tracking

Researchers developed Passive Heart-Rate Monitoring, a deep-learning smartphone system that estimates heart rate and daily resting heart rate from eight-second facial videos captured during normal phone use. Validated on more than 160,000 videos, the system met accuracy targets across skin-tone groups, although usable measurement rates were lower in the darkest skin-tone group and clinical use still requires further testing.

2 Jun 2026

AI-assisted model based on blood proteins could help predict retinal degeneration in diabetics

An AI-assisted model based on 71 different blood proteins could help doctors better predict retinal degeneration in diabetic patients before symptoms occur, according to a study published June 2nd in the open access journal PLOS Medicine by Huangdong Li from the Guangdong Provincial Clinical Research Center for Ocular Diseases in Guangzhou, China, and colleagues.

2 Jun 2026