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FDA schedules meeting to discuss emergency use authorization of COVID-19 vaccine from Pfizer

Today, the U.S. Food and Drug Administration issued an emergency use authorization (EUA) for casirivimab and imdevimab to be administered together for the treatment of mild to moderate COVID-19 in adults and pediatric patients (12 years of age or older weighing at least 40 kilograms [about 88 pounds]) with positive results of direct SARS-CoV-2 viral testing and who are at high risk for progressing to severe COVID-19.

23 Nov 2020

Researchers discover mechanism by which abnormal proteins unleash toxicity in neurodegenerative diseases

Thanks to modern medicine, humans tend to live much longer than before. Unfortunately, this also opens a wider window to develop chronic diseases with late onset, such as neurodegenerative diseases.

23 Nov 2020

New device can allow patients to perform glaucoma eye test at home

Glaucoma is a chronic condition that affects cells at the back of the eye. It is the leading cause of irreversible blindness worldwide, and is responsible for 1 in 10 cases of serious sight impairment in the UK.

22 Nov 2020

Inflammatory factors that aggravate COVID-19 may come from adipose tissue

There is growing evidence that adipose tissue plays a key role in the aggravation of COVID-19. One of the theories under investigation is that fat cells (adipocytes) act as a reservoir for SARS-CoV-2 and increase viral load in obese or overweight individuals.

20 Nov 2020

Move to ban sales of new petrol and diesel cars could benefit the health of professional drivers

As the Government announced today it will bring forward a ban on sales of new petrol and diesel cars by five years to 2030, new research shows professional drivers would benefit from improvements to their respiratory health, reducing their risks of cancers caused by their work.

20 Nov 2020

National health groups offer support for COPD patients and caregivers amid pandemic

An estimated 16.4 million Americans are living with chronic obstructive pulmonary disease – a chronic lung disease that makes it difficult to breathe – which places them at an increased risk for more severe illness from COVID-19.

20 Nov 2020

EULAR Consultation Service helps address rheumatic, musculoskeletal diseases

Chronic and often painful rheumatic and musculoskeletal diseases disable millions of people in the EU and worldwide.

20 Nov 2020

High cost of drugs could lead to more than 1.1 million deaths among Medicare recipients

More than 1.1 million Medicare patients could die over the next decade because they cannot afford to pay for their prescription medications, according to a new study released today by the West Health Policy Center, a nonprofit and nonpartisan policy research group and Xcenda, the research arm of the drug distributor AmerisourceBergen.

19 Nov 2020

New druggable target for heart failure in neonates and infants identified

Researchers have identified a new druggable target for heart failure in neonates and infants, a condition for which there has been no specific treatment.

19 Nov 2020

New model provides better understanding of lung infections in patients with cystic fibrosis

For young people with cystic fibrosis, lung infection with Staphylococcus aureus, MRSA, is common and is treated with antibiotics in the hope that this will prevent a decline in lung function.

19 Nov 2020

Researchers uncover potential new target to fight inflammatory diseases

An international team of researchers have uncovered a drug-like compound that blocks a crucial inflammatory pathway, potentially paving the way for a new treatment for a host of diseases - including COVID-19.

19 Nov 2020

Study shows link between COPD and the gut microbiome

Research led by the Centenary Institute, the University of Technology Sydney and the University of Queensland has shown for the first time a link between chronic obstructive pulmonary disease (COPD), an often fatal lung condition, and the gut microbiome.

19 Nov 2020

Immune mechanism responsible for adverse inflammatory reactions after stem cell transplant identified

In the treatment of leukemia, stem cell transplantation subsequent to chemotherapy and radiation can often engender severe adverse inflammatory reactions - especially in the skin or in the gut, since these so-called barrier organs are more frequently affected.

19 Nov 2020

Researchers use optogenetics to mitigate addiction-related behaviors

In the United States alone, over 14 million adults suffer from alcohol use disorder. For those that seek treatment, 90% will experience at least one relapse within the first four years.

19 Nov 2020

CRISPR/Cas9 system is highly effective in treating metastatic cancers

Researchers at Tel Aviv University (TAU) have demonstrated that the CRISPR/Cas9 system is very effective in treating metastatic cancers, a significant step on the way to finding a cure for cancer.

19 Nov 2020

Decades of research into racial, ethnic health disparities fail to resolve disproportionate health outcomes

When it comes to understanding why children from non-white race groups have such poor health outcomes compared with their white counterparts, it's time for researchers to look beyond their genes and delve deeper into social factors, according to a commentary published today in the journal Pediatrics.

19 Nov 2020

Machine learning can fill significant gap in Canadian public health data

Machine learning can be used to fill a significant gap in Canadian public health data related to ethnicity and Aboriginal status, according to research published today in PLOS ONE by a University of Alberta research epidemiologist.

19 Nov 2020

Study examines the diagnosis of exercise‐induced respiratory symptoms in children

Exercise-induced respiratory symptoms are common in childhood, and it can be difficult to diagnose their cause.

18 Nov 2020

Machine learning-based prediction model may enable early diagnosis of opioid use disorder

Researchers have used machine learning, a type of artificial intelligence, to develop a prediction model for the early diagnosis of opioid use disorder.

18 Nov 2020

SARS-CoV-2 causes a unique cytokine storm, study finds

A new study published on the preprint server medRxiv* in November 2020 reports some of the unique elements of COVID-19-induced CRS and how understanding these distinctive characteristics of the disease could help in formulating specific interventions and therapies.

18 Nov 2020

Chronic News and Research

FDA schedules meeting to discuss emergency use authorization of COVID-19 vaccine from Pfizer

Researchers discover mechanism by which abnormal proteins unleash toxicity in neurodegenerative diseases

New device can allow patients to perform glaucoma eye test at home

Inflammatory factors that aggravate COVID-19 may come from adipose tissue

Move to ban sales of new petrol and diesel cars could benefit the health of professional drivers

National health groups offer support for COPD patients and caregivers amid pandemic

EULAR Consultation Service helps address rheumatic, musculoskeletal diseases

High cost of drugs could lead to more than 1.1 million deaths among Medicare recipients

New druggable target for heart failure in neonates and infants identified

New model provides better understanding of lung infections in patients with cystic fibrosis

Researchers uncover potential new target to fight inflammatory diseases

Study shows link between COPD and the gut microbiome

Immune mechanism responsible for adverse inflammatory reactions after stem cell transplant identified

Researchers use optogenetics to mitigate addiction-related behaviors

CRISPR/Cas9 system is highly effective in treating metastatic cancers

Decades of research into racial, ethnic health disparities fail to resolve disproportionate health outcomes

Machine learning can fill significant gap in Canadian public health data

Study examines the diagnosis of exercise‐induced respiratory symptoms in children

Machine learning-based prediction model may enable early diagnosis of opioid use disorder

SARS-CoV-2 causes a unique cytokine storm, study finds

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

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