Chronic News and Research

RSS

Pfizer/BioNTech COVID-19 vaccine candidate BNT162b2 profiled for large scale clinical trials

Although two RNA-based severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine candidates elicited similar, dose-dependent neutralizing antibody titers in both younger and older adults, a recent study by researchers from the U.S. and Germany has shown that BNT162b2 is associated with less systemic reactogenicity in elderly individuals – supporting its selection for further phase 2/3 clinical trials. The study is currently available on medRxiv* preprint server.

23 Aug 2020

Scientific review on on link between air pollution and COVID-19

Researchers at Harvard T. H. Chan School of Public Health, Harvard University, and the Dana-Farber Cancer Institute have conducted a “state-of-the-science” review of the evidence available on potential associations between exposure to air pollution and health outcomes in coronavirus disease 2019 (COVID-19).

23 Aug 2020

Doctors with disabilities call for a paradigm shift to make medical education, profession more inclusive

Doctors treat and heal patients, but they are seldom seen as people who may themselves require care or accommodation. Medics with disabilities are now calling for a paradigm shift in this mindset to make medical education and the profession more inclusive.

21 Aug 2020

COVID-19 patients most likely readmitted to hospital for respiratory distress, study finds

This study describes characteristics of patients with COVID-19 who returned to the ER or required readmission to the hospital within 14 days of being discharged. Understanding what conditions impact these patient outcomes can help improve care during the hospital stay and after discharge.

21 Aug 2020

VUMC receives $34 million grant for nationwide convalescent plasma study

Vanderbilt University Medical Center has been awarded a one-year, $34-million grant by the National Center for Advancing Translational Sciences, part of the National Institutes of Health, to conduct a nationwide study of "convalescent plasma" as a treatment for COVID-19.

21 Aug 2020

Adolescents with “elevated" hunger hormone are more likely to develop post-traumatic stress disorder

Chronic stress increases a blood-based hormone called acyl-ghrelin for years after the initial traumatic stressor exposure in some adolescents, and those with elevated levels of the hormone are more likely to develop post-traumatic stress disorder (PTSD) and to experience more severe cases of the condition, according to a study conducted by researchers at the Icahn School of Medicine at Mount Sinai and published August 20 in JAMA Network Open.

21 Aug 2020

New York Blood Center receives $15.6 million NIH grant for sickle cell transfusion research

The National Heart, Lung and Blood Institute of the National Institutes of Health has awarded a five-year grant of $15.6 million to Karina Yazdanbakhsh, PhD, of New York Blood Center’s Lindsley F. Kimball Research Institute, to lead a collaborative research program studying the consequences of transfusions in patients with sickle cell disease and developing strategies to optimize transfusion management for this patient group.

21 Aug 2020

Family history of alcoholism increases risk of developing alcohol use disorder

The statistics are sobering. More than 14 million American adults suffer from some form of alcohol use disorder (AUD), a chronic inability to stop or control alcohol use despite the negative consequences.

21 Aug 2020

Study: Biological components combined with socioeconomic factors increases tooth decay

Nationally, rates of early childhood caries, or tooth decay, among Hispanic, American Indian, Native Hawaiian and Other Pacific Islander children are almost double those of white children, making it the most prevalent chronic disease among these populations--occurring five times as frequently as asthma.

21 Aug 2020

Study: More than 20% of nursing homes in the U.S. still report staff, PPE shortages

Nearly half of all COVID-19 deaths in the United States have occurred among nursing home residents, whose age, chronic medical conditions, and congregate living quarters place them and their caregivers at high risk of contracting the disease.

20 Aug 2020

Fewer rhinovirus infections in Philadelphia after COVID-19 stay-at-home orders

Philadelphia and its surrounding counties issued a series of "stay-at-home" orders on March 17, 2020 in an effort to curb the spread of COVID-19.

20 Aug 2020

Post-mortem study of dead COVID-19 patients finds lung damage and blood clots

A new post-mortem study of patients who have died from COVID-19 found severe damage to the lungs and signs of blood clotting in major organs.

20 Aug 2020

A metabolic enzyme shows great potential as target for immunotherapies

The metabolic enzyme IL4I1 (Interleukin-4-Induced-1) promotes the spread of tumor cells and suppresses the immune system.

20 Aug 2020

IUPUI study proposes a primary prevention strategy for substance use disorder

There are well documented risk factors associated with developing substance use disorder across all age groups.

20 Aug 2020

Scientists investigate the role of contractility and microbiota in chronic constipation

Chronic constipation (CC) remains a serious medical and social problem because the complexity of diagnosis, the lack of a single approach to treatment, and unsatisfactory treatment results.

20 Aug 2020

Cells lining the nose are key entry point for coronavirus, shows study

Scientists at Johns Hopkins Medicine, experimenting with a small number of human cell samples, report that the "hook" of cells used by SARS-CoV-2 to latch onto and infect cells is up to 700 times more prevalent in the olfactory supporting cells lining the inside of the upper part of the nose than in the lining cells of the rest of the nose and windpipe that leads to the lungs.

20 Aug 2020

Girls with anorexia nervosa can have stunted growth

Girls with anorexia nervosa can have stunted growth and may not reach their full height potential, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

20 Aug 2020

Inhibition of key receptor implicated in post-stroke damage and recovery

Many people who suffer a stroke are permanently disabled. Stroke remains the leading cause of long-term disability in the United States.

20 Aug 2020

Older adults with pre-existing depression exhibit resilience to stress during COVID-19

A study involving older adults with pre-existing major depressive disorder living in Los Angeles, New York, Pittsburgh, and St Louis found no increase in depression and anxiety during the COVID-19 pandemic.

19 Aug 2020

New approach to chronic pain treatment could bring relief

Something like a quarter of the world's population suffers from chronic pain at some point in their lives. As opposed to acute pain - for example, the feeling after hitting your finger with a hammer - chronic pain may not even have a clear cause, and it can linger for years or lifetimes.

19 Aug 2020

Chronic News and Research

Pfizer/BioNTech COVID-19 vaccine candidate BNT162b2 profiled for large scale clinical trials

Scientific review on on link between air pollution and COVID-19

Doctors with disabilities call for a paradigm shift to make medical education, profession more inclusive

COVID-19 patients most likely readmitted to hospital for respiratory distress, study finds

VUMC receives $34 million grant for nationwide convalescent plasma study

Adolescents with “elevated" hunger hormone are more likely to develop post-traumatic stress disorder

New York Blood Center receives $15.6 million NIH grant for sickle cell transfusion research

Family history of alcoholism increases risk of developing alcohol use disorder

Study: Biological components combined with socioeconomic factors increases tooth decay

Study: More than 20% of nursing homes in the U.S. still report staff, PPE shortages

Fewer rhinovirus infections in Philadelphia after COVID-19 stay-at-home orders

Post-mortem study of dead COVID-19 patients finds lung damage and blood clots

A metabolic enzyme shows great potential as target for immunotherapies

IUPUI study proposes a primary prevention strategy for substance use disorder

Scientists investigate the role of contractility and microbiota in chronic constipation

Cells lining the nose are key entry point for coronavirus, shows study

Girls with anorexia nervosa can have stunted growth

Inhibition of key receptor implicated in post-stroke damage and recovery

Older adults with pre-existing depression exhibit resilience to stress during COVID-19

New approach to chronic pain treatment could bring relief

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Latest News